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We study explained variation under the additive hazards regression model for right-censored data. We consider different approaches for developing such a measure, and focus on one that estimates the proportion of variation in the failure…

应用统计 · 统计学 2020-09-02 Denise Rava , Ronghui Xu

A population-averaged additive subdistribution hazards model is proposed to assess the marginal effects of covariates on the cumulative incidence function and to analyze correlated failure time data subject to competing risks. This approach…

统计方法学 · 统计学 2023-08-23 Xinyuan Chen , Denise Esserman , Fan Li

A comprehensive, unified approach to modeling arbitrarily censored spatial survival data is presented for the three most commonly-used semiparametric models: proportional hazards, proportional odds, and accelerated failure time. Unlike many…

应用统计 · 统计学 2017-07-04 Haiming Zhou , Timothy Hanson

A simple yet effective way of modeling survival data with cure fraction is by considering Box-Cox transformation cure model (BCTM) that unifies mixture and promotion time cure models. In this article, we numerically study the statistical…

统计方法学 · 统计学 2023-10-25 Suvra Pal , Sandip Barui

Interval censoring arises frequently in clinical, epidemiological, financial, and sociological studies, where the event or failure of interest is known only to occur within an interval induced by periodic monitoring. We formulate the…

统计方法学 · 统计学 2016-03-01 Donglin Zeng , Lu Mao , D. Y. Lin

Popular parametric and semiparametric hazards regression models for clustered survival data are inappropriate and inadequate when the unknown effects of different covariates and clustering are complex. This calls for a flexible modeling…

应用统计 · 统计学 2021-03-16 Piyali Basak , Antonio R. Linero , Debajyoti SInha , Stuart Lipsitz

Semiparametric regression offers a flexible framework for modeling non-linear relationships between a response and covariates. A prime example are generalized additive models where splines (say) are used to approximate non-linear functional…

统计理论 · 数学 2018-10-05 Francis K. C. Hui , Chong You , Han Lin Shang , Samuel Müller

Censored quantile regression has emerged as a prominent alternative to classical Cox's proportional hazards model or accelerated failure time model in both theoretical and applied statistics. While quantile regression has been extensively…

统计方法学 · 统计学 2024-08-27 Taehwa Choi , Seohyeon Park , Hunyong Cho , Sangbum Choi

In contrast to the popular Cox model which presents a multiplicative covariate effect specification on the time to event hazards, the semiparametric additive risks model (ARM) offers an attractive additive specification, allowing for direct…

统计方法学 · 统计学 2022-03-21 Tong Wang , Dipankar Bandyopadhyay , Samiran Sinha

In this paper, we extend the vertical modeling approach for the analysis of survival data with competing risks to incorporate a cured fraction in the population, that is, a proportion of the population for which none of the competing events…

统计方法学 · 统计学 2015-08-18 M. A. Nicolaie , J. M. G. Taylor , C. Legrand

Clustered competing risks data are commonly encountered in multicenter studies. The analysis of such data is often complicated due to informative cluster size, a situation where the outcomes under study are associated with the size of the…

统计方法学 · 统计学 2021-04-26 Wenxian Zhou , Giorgos Bakoyannis , Ying Zhang , Constantin T. Yiannoutsos

Partially observed cured data occur in the analysis of spontaneous abortion (SAB) in observational studies in pregnancy. In contrast to the traditional cured data, such data has an observable `cured' portion as women who do not abort…

统计方法学 · 统计学 2016-09-02 Jue Hou , Christina D. Chambers , Ronghui Xu

We consider nonparametric estimation of cure-rate based on mixture model under Case-1 interval censoring. We show that the nonparametric maximum-likelihood estimator (NPMLE) of cure-rate is non-unique as well as inconsistent, and propose…

统计理论 · 数学 2007-06-13 Arusharka Sen , Fang Tan

Assuming some regression model, it is common to study the conditional distribution of survival given covariates. Here, we consider the impact of further conditioning, specifically conditioning on a marginal survival function, known or…

应用统计 · 统计学 2016-10-11 Roxane Duroux , Cécile Chauvel , John O'Quigley

In this paper the regression discontinuity design is adapted to the survival analysis setting with right-censored data, studied in an intensity based counting process framework. In particular, a local polynomial regression version of the…

统计方法学 · 统计学 2022-10-07 Emil Aas Stoltenberg

The conditional survival function of a time-to-event outcome subject to censoring and truncation is a common target of estimation in survival analysis. This parameter may be of scientific interest and also often appears as a nuisance in…

统计方法学 · 统计学 2024-08-20 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

Current status data are commonly encountered in medical and epidemiological studies in which the failure time for study units is the outcome variable of interest. Data of this form are characterized by the fact that the failure time is not…

统计方法学 · 统计学 2019-04-25 Yan Liu , Minggen Lu , Christopher S. McMahan

Social network analysis presupposes that observed social behavior is influenced by an unobserved network. Traditional approaches to inferring the latent network use pairwise descriptive statistics that rely on a variety of measures of…

应用统计 · 统计学 2018-09-03 Charles Weko , Yunpeng Zhao

Nonlinear Mixed effects models are hidden variables models that are widely used in many fields such as pharmacometrics. In such models, the distribution characteristics of hidden variables can be specified by including several parameters…

统计方法学 · 统计学 2021-10-19 Edouard Ollier

Multistate models can be used to describe transitions over time across states. In the presence of interval-censored times for transitions, the likelihood is constructed using transition probabilities. Models are specified using proportional…

统计方法学 · 统计学 2018-01-22 Robson J. M. Machado , Ardo van den Hout , Giampiero Marra