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相关论文: Resource-Limited Automated Ki67 Index Estimation i…

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The nuclear protein Ki-67 and Tumor infiltrating lymphocytes (TILs) have been introduced as prognostic factors in predicting tumor progression and its treatment response. The value of the Ki-67 index and TILs in approach to heterogeneous…

Ki-67 is a nuclear protein that can be produced during cell proliferation. The Ki67 index is a valuable prognostic variable in several kinds of cancer. In breast cancer, the index is even routinely checked in many patients. Currently,…

图像与视频处理 · 电气工程与系统科学 2022-09-28 Hsiang-Wei Huang , Wen-Tsung Huang , Hsun-Heng Tsai

In this paper, we introduce PathRTM, a novel deep neural network detector based on RTMDet, for automated KI-67 proliferation and tumor-infiltrated lymphocyte estimation. KI-67 proliferation and tumor-infiltrated lymphocyte estimation play a…

定量方法 · 定量生物学 2023-05-03 Steven Zvi Lapp , Eli David , Nathan S. Netanyahu

The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insights into the oncogenic features modulating drug response. A recent screening of ~1,000 cancer cell lines to a collection of…

The Ki-67 proliferation index is an essential biomarker that helps pathologists to diagnose and select appropriate treatments. However, automatic evaluation of Ki-67 is difficult due to nuclei overlapping and complex variations in their…

图像与视频处理 · 电气工程与系统科学 2022-03-16 Khaled Benaggoune , Zeina Al Masry , Jian Ma , Christine Devalland , L. H Mouss , Noureddine Zerhouni

Precise breast cancer classification on histopathological images has the potential to greatly improve the diagnosis and patient outcome in oncology. The data imbalance problem largely stems from the inherent imbalance within medical image…

图像与视频处理 · 电气工程与系统科学 2024-11-28 Majid Behzadpour , Bengie L. Ortiz , Ebrahim Azizi , Kai Wu

Nuclei detection is a key task in Ki67 proliferation index estimation in breast cancer images. Deep learning algorithms have shown strong potential in nuclei detection tasks. However, they face challenges when applied to pathology images…

图像与视频处理 · 电气工程与系统科学 2022-07-19 Seyed Hossein Mirjahanmardi , Melanie Dawe , Anthony Fyles , Wei Shi , Fei-Fei Liu , Susan Done , April Khademi

The advancement of computer-aided detection systems had a significant impact on clinical analysis and decision-making on human disease. Lung cancer requires more attention among the numerous diseases being examined because it affects both…

图像与视频处理 · 电气工程与系统科学 2023-05-24 Jafar Abdollahi

Breast cancer molecular subtypes classification plays an import role to sort patients with divergent prognosis. The biomarkers used are Estrogen Receptor (ER), Progesterone Receptor (PR), HER2, and Ki67. Based on these biomarkers expression…

机器学习 · 计算机科学 2023-10-24 Matheus del-Valle , Emerson Soares Bernardes , Denise Maria Zezell

Polygenic risk scores (PRS) estimate the genetic risk of an individual for a complex disease based on many genetic variants across the whole genome. In this study, we compared a series of computational models for estimation of breast cancer…

定量方法 · 定量生物学 2023-07-26 Adrien Badré , Li Zhang , Wellington Muchero , Justin C. Reynolds , Chongle Pan

Purpose Tumor-infiltrating lymphocytes (TILs) have significant prognostic values in cancers. However, very few automated, deep-learning-based TIL scoring algorithms have been developed for colorectal cancers (CRC). Methods We developed an…

定量方法 · 定量生物学 2022-09-16 Anran Liu , Xingyu Li , Hongyi Wu , Bangwei Guo , Jitendra Jonnagaddala , Hong Zhang , Xu Steven Xu

Breast cancer is a common fatal disease for women. Early diagnosis and detection is necessary in order to improve the prognosis of breast cancer affected people. For predicting breast cancer, several automated systems are already developed…

图像与视频处理 · 电气工程与系统科学 2020-06-03 Subrato Bharati , Prajoy Podder , M. Rubaiyat Hossain Mondal

Oral cancer presents a formidable challenge in oncology, necessitating early diagnosis and accurate prognosis to enhance patient survival rates. Recent advancements in machine learning and data mining have revolutionized traditional…

机器学习 · 计算机科学 2025-06-13 Mohammad Subhi Al-Batah , Muhyeeddin Alqaraleh , Mowafaq Salem Alzboon

Ki67 is an important biomarker for breast cancer. Classification of positive and negative Ki67 cells in histology slides is a common approach to determine cancer proliferation status. However, there is a lack of generalizable and accurate…

计算机视觉与模式识别 · 计算机科学 2018-06-29 Priya Lakshmi Narayanan , Shan E Ahmed Raza , Andrew Dodson , Barry Gusterson , Mitchell Dowsett , Yinyin Yuan

Reliable quantification of Ki-67, a key proliferation marker in breast cancer, is essential for molecular subtyping and informed treatment planning. Conventional approaches, including visual estimation and manual counting, suffer from…

图像与视频处理 · 电气工程与系统科学 2025-03-26 Deepti Madurai Muthu , Priyanka S , Lalitha Rani N , P. G. Kubendran Amos

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

图像与视频处理 · 电气工程与系统科学 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning

We suggest that deep learning can be used for pre-screening cancer by analyzing demographic and anthropometric information of patients, as well as biological markers obtained from routine blood samples and relative risks obtained from…

机器学习 · 统计学 2023-02-07 Rolando Gonzales Martinez , Daan-Max van Dongen

Treatments for breast cancer have continued to evolve and improve in recent years, resulting in a substantial increase in survival rates, with approximately 80\% of patients having a 10-year survival period. Given the serious impact that…

计算机视觉与模式识别 · 计算机科学 2022-05-26 Wilson Silva , Maria Carvalho , Carlos Mavioso , Maria J. Cardoso , Jaime S. Cardoso

The study explores Artificial Intelligence (AI) powered modeling to predict the evolution of cancer tumor cells in mice under different forms of treatment. The AI models are analyzed against varying ambient and systemic parameters, e.g.…

This paper provides a critical review of the literature on deep learning applications in breast tumor diagnosis using ultrasound and mammography images. It also summarizes recent advances in computer-aided diagnosis (CAD) systems, which…

图像与视频处理 · 电气工程与系统科学 2020-10-05 Yuliana Jiménez-Gaona , María José Rodríguez-Álvarez , Vasudevan Lakshminarayanan
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