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Neuropsychiatric symptoms (NPS) such as depression and apathy are common in Alzheimer's disease (AD) and often precede cognitive decline. NPS assessments hold promise as early detection markers due to their correlation with disease…

计算机视觉与模式识别 · 计算机科学 2026-04-02 Synne Hjertager Osenbroch , Lisa Ramona Rosvold , Yao Lu , Alvaro Fernandez-Quilez

It is acknowledged that the most common cause of dementia worldwide is Alzheimer's disease (AD). This condition progresses in severity from mild to severe and interferes with people's everyday routines. Early diagnosis plays a critical role…

图像与视频处理 · 电气工程与系统科学 2024-09-30 Sajjad Aghasi Javid , Mahmood Mohassel Feghhi

Accurate diagnosis of Alzheimer's disease (AD) is both challenging and time consuming. With a systematic approach for early detection and diagnosis of AD, steps can be taken towards the treatment and prevention of the disease. This study…

机器学习 · 计算机科学 2022-12-12 Harshit Parmar , Eric Walden

Gait analysis, an expanding research area, employs non invasive sensors and machine learning techniques for a range of applicatio ns. In this study, we concentrate on gait analysis for detecting cognitive decline in Parkinson's disease (PD)…

信号处理 · 电气工程与系统科学 2023-06-13 Abdullah Alharthi

Eye-tracking is an accessible and non-invasive technology that provides information about a subject's motor and cognitive abilities. As such, it has proven to be a valuable resource in the study of neurodegenerative diseases such as…

机器学习 · 计算机科学 2023-11-29 Gonzalo Uribarri , Simon Ekman von Huth , Josefine Waldthaler , Per Svenningsson , Erik Fransén

Alzheimer's Disease destroys brain cells causing people to lose their memory, mental functions and ability to continue daily activities. It is a severe neurological brain disorder which is not curable, but earlier detection of Alzheimer's…

计算机视觉与模式识别 · 计算机科学 2017-12-21 Jyoti Islam , Yanqing Zhang

Parkinson's disease (PD) shows heterogeneous, evolving brain-morphometry patterns. Modeling these longitudinal trajectories enables mechanistic insight, treatment development, and individualized 'digital-twin' forecasting. However, existing…

Parkinson's disease (PD), a prevalent neurodegenerative disorder, significantly affects patients' daily functioning and social interactions. To facilitate a more efficient and accessible diagnostic approach for PD, we propose a dynamic…

计算机视觉与模式识别 · 计算机科学 2025-12-11 Xiaochen Huang , Xiaochen Bi , Cuihua Lv , Xin Wang , Haoyan Zhang , Wenjing Jiang , Xin Ma , Yibin Li

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, structural brain changes, and genetic predispositions. This study leverages machine-learning and statistical techniques to investigate…

应用统计 · 统计学 2025-10-29 Riddhik Basu , Arkaprava Roy

This paper deals with a complex acoustic analysis of phonation in patients with Parkinson's disease (PD) with a special focus on estimation of disease progress that is described by 7 different clinical scales ,e. g. Unified Parkinson's…

Alzheimer's Disease (AD) is a severe brain disorder, destroying memories and brain functions. AD causes chronically, progressively, and irreversibly cognitive declination and brain damages. The reliable and effective evaluation of early…

图像与视频处理 · 电气工程与系统科学 2021-01-07 Kuo Yang , Emad A. Mohammed

Early and accurate identification of parkinsonian syndromes (PS) involving presynaptic degeneration from non-degenerative variants such as Scans Without Evidence of Dopaminergic Deficit (SWEDD) and tremor disorders, is important for…

应用统计 · 统计学 2017-03-07 R. Prashanth , Sumantra Dutta Roy , Pravat K. Mandal , Shantanu Ghosh

Alzheimer's Disease (AD) ravages the cognitive ability of more than 5 million Americans and creates an enormous strain on the health care system. This paper proposes a machine learning predictive model for AD development without medical…

定量方法 · 定量生物学 2020-06-17 Courtney Cochrane , David Castineira , Nisreen Shiban , Pavlos Protopapas

Dementia is a syndrome characterised by the decline of different cognitive abilities. Alzheimer's Disease (AD) is the most common dementia affecting cognitive domains such as memory and learning, perceptual-motion or executive function.…

计算机视觉与模式识别 · 计算机科学 2018-10-26 Juan Manuel Fernández Montenegro

Efficient early diagnosis is paramount in addressing the complexities of Parkinson's disease because timely intervention can substantially mitigate symptom progression and improve patient outcomes. In this paper, we present a pioneering…

信号处理 · 电气工程与系统科学 2024-04-25 Alireza Rashnu , Armin Salimi-Badr

Parkinson's disease (PD) is the second most frequent neurodegenerative disease with prevalence among general population reaching 0.1-1 %, and an annual incidence between 1.3-2.0/10000 inhabitants. The mean age at diagnosis of PD is 55 and…

In order to find effective treatments for Alzheimer's disease (AD), we need to identify subjects at risk of AD as early as possible. To this end, recently developed disease progression models can be used to perform early diagnosis, as well…

定量方法 · 定量生物学 2020-03-11 Razvan V. Marinescu

Parkinson's disease (PD), characterized by its incurable nature, rapid progression, and severe disability, poses significant challenges to the lives of patients and their families. Given the aging population, the need for early detection of…

计算机视觉与模式识别 · 计算机科学 2025-06-24 Wei Huang , Yinxuan Xu , Yintao Zhou , Zhengyu Li , Jing Huang , Meng Pang

In this paper, we introduce a novel approach for diagnosis of Parkinson's Disease (PD) based on deep Echo State Networks (ESNs). The identification of PD is performed by analyzing the whole time-series collected from a tablet device during…

机器学习 · 计算机科学 2018-02-20 Claudio Gallicchio , Alessio Micheli , Luca Pedrelli

Alzheimer's disease is a degenerative brain disease. Being the primary cause of Dementia in adults and progressively destroys brain memory. Though Alzheimer's disease does not have a cure currently, diagnosing it at an earlier stage will…

机器学习 · 计算机科学 2023-02-17 Shrish Pellakur , Nelly Elsayed , Zag ElSayed , Murat Ozer