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Molecular processes of neuronal learning have been well-described. However, learning mechanisms of non-neuronal cells have not been fully understood at the molecular level. Here, we discuss molecular mechanisms of cellular learning,…

Cognitive ageing seems to be a story of global degradation. As one ages there are a number of physical, chemical and biological changes that take place. Therefore it is logical to assume that the brain is no exception to this phenomenon.…

适应与自组织系统 · 物理学 2014-08-07 Sakyasingha Dasgupta

Hebbian theory seeks to explain how the neurons in the brain adapt to stimuli, to enable learning. An interesting feature of Hebbian learning is that it is an unsupervised method and as such, does not require feedback, making it suitable in…

神经元与认知 · 定量生物学 2022-06-07 Jakub Fil , Neil Dalchau , Dominique Chu

The human brain is a complex system that is fascinating scientists since a long time. Its remarkable capabilities include categorization of concepts, retrieval of memories and creative generation of new examples. At the same time, modern…

无序系统与神经网络 · 物理学 2024-10-10 Enrico Ventura

In this work, we study the dynamic range in a neuronal network modelled by cellular automaton. We consider deterministic and non-deterministic rules to simulate electrical and chemical synapses. Chemical synapses have an intrinsic…

Deep artificial neural networks have surpassed human-level performance across a diverse array of complex learning tasks, establishing themselves as indispensable tools in both social applications and scientific research. Despite these…

无序系统与神经网络 · 物理学 2025-09-03 Chuanbo Liu , Jin Wang

The aim of the present paper is to study the effects of Hebbian learning in random recurrent neural networks with biological connectivity, i.e. sparse connections and separate populations of excitatory and inhibitory neurons. We furthermore…

神经元与认知 · 定量生物学 2007-06-19 Benoit Siri , Mathias Quoy , Bruno Delord , Bruno Cessac , Hugues Berry

Recurrent neural networks in the chaotic regime exhibit complex dynamics reminiscent of high-level cortical activity during behavioral tasks. However, existing training methods for such networks are either biologically implausible, or…

神经元与认知 · 定量生物学 2015-12-09 Thomas Miconi

Continual Learning aims to bring machine learning into a more realistic scenario, where tasks are learned sequentially and the i.i.d. assumption is not preserved. Although this setting is natural for biological systems, it proves very…

神经与进化计算 · 计算机科学 2022-07-12 Paweł Morawiecki , Andrii Krutsylo , Maciej Wołczyk , Marek Śmieja

Lateral inhibition models coupled with Hebbian plasticity have been shown to learn factorised causal representations of input stimuli, for instance, oriented edges are learned from natural images. Currently, these models require the…

神经元与认知 · 定量生物学 2025-01-07 Henrique Reis Aguiar , Matthias H. Hennig

Brains learn to represent information from a large set of stimuli, typically by weak supervision. Unsupervised learning is therefore a natural approach for exploring the design of biological neural networks and their computations.…

神经元与认知 · 定量生物学 2025-10-17 Roy Urbach , Elad Schneidman

The complexity of the cells can be described and understood by a number of networks such as protein-protein interaction, cytoskeletal, organelle, signalling, gene transcription and metabolic networks. All these networks are highly dynamic…

分子网络 · 定量生物学 2007-07-26 Mate S. Szalay , Istvan A. Kovacs , Tamas Korcsmaros , Csaba Bode , Peter Csermely

Humans can learn several tasks in succession with minimal mutual interference but perform more poorly when trained on multiple tasks at once. The opposite is true for standard deep neural networks. Here, we propose novel computational…

神经元与认知 · 定量生物学 2022-09-07 Timo Flesch , David G. Nagy , Andrew Saxe , Christopher Summerfield

Hebbian plasticity is a powerful principle that allows biological brains to learn from their lifetime experience. By contrast, artificial neural networks trained with backpropagation generally have fixed connection weights that do not…

神经与进化计算 · 计算机科学 2016-10-20 Thomas Miconi

The classic paradigms for learning and memory recall focus on strengths of synaptic couplings and how these can be modulated to encode memories. In a previous paper [A. K. Behera, M. Rao, S. Sastry, and S. Vaikuntanathan, Physical Review X…

无序系统与神经网络 · 物理学 2024-10-10 Agnish Kumar Behera , Matthew Du , Uday Jagadisan , Srikanth Sastry , Madan Rao , Suriyanarayanan Vaikuntanathan

Neural networks are commonly trained to make predictions through learning algorithms. Contrastive Hebbian learning, which is a powerful rule inspired by gradient backpropagation, is based on Hebb's rule and the contrastive divergence…

机器学习 · 计算机科学 2018-06-21 Georgios Detorakis , Travis Bartley , Emre Neftci

The plasticity property of biological neural networks allows them to perform learning and optimize their behavior by changing their configuration. Inspired by biology, plasticity can be modeled in artificial neural networks by using Hebbian…

神经与进化计算 · 计算机科学 2020-12-21 Anil Yaman , Giovanni Iacca , Decebal Constantin Mocanu , George Fletcher , Mykola Pechenizkiy

Drug resistance and metastasis - the major complications in cancer - both entail adaptation of cancer cells to stress, whether a drug or a lethal new environment. Intriguingly, these adaptive processes share similar features that cannot be…

分子网络 · 定量生物学 2021-09-28 Aseel Shomar , Omri Barak , Naama Brenner

Learning and the ability to learn are important factors in development and evolutionary processes [1]. Depending on the level, the complexity of learning can strongly vary. While associative learning can explain simple learning behaviour…

神经元与认知 · 定量生物学 2007-05-23 Reimer Kuehn , Ion-Olimpiu Stamatescu

A feed-forward neural net with adaptable synaptic weights and fixed, zero or non-zero threshold potentials is studied, in the presence of a global feedback signal that can only have two values, depending on whether the output of the network…

无序系统与神经网络 · 物理学 2009-11-10 J. Bedaux , W. A. van Leeuwen
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