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Annotating cancerous regions in whole-slide images (WSIs) of pathology samples plays a critical role in clinical diagnosis, biomedical research, and machine learning algorithms development. However, generating exhaustive and accurate…

计算机视觉与模式识别 · 计算机科学 2022-06-09 Zhenzhen Wang , Carla Saoud , Sintawat Wangsiricharoen , Aaron W. James , Aleksander S. Popel , Jeremias Sulam

Computational pathology involves the digitization of stained tissues into whole-slide images (WSIs) that contain billions of pixels arranged as contiguous patches. Statistical analysis of WSIs largely focuses on classification via multiple…

计算机视觉与模式识别 · 计算机科学 2026-03-24 So Won Jeong , Veronika Ročková

Histomorphology is crucial in cancer diagnosis. However, existing whole slide image (WSI) classification methods struggle to effectively incorporate histomorphology information, limiting their ability to capture key pathological features.…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Baizhi Wang , Rui Yan , Wenxin Ma , Xu Zhang , Yuhao Wang , Xiaolong Li , Yunjie Gu , Zihang Jiang , S. Kevin Zhou

A new multi-attention based method for solving the MIL problem (MAMIL), which takes into account the neighboring patches or instances of each analyzed patch in a bag, is proposed. In the method, one of the attention modules takes into…

机器学习 · 计算机科学 2021-12-14 Andrei V. Konstantinov , Lev V. Utkin

In multiple instance multiple label learning, each sample, a bag, consists of multiple instances. To alleviate labeling complexity, each sample is associated with a set of bag-level labels leaving instances within the bag unlabeled. This…

机器学习 · 计算机科学 2021-07-28 Tam Nguyen , Raviv Raich

In histopathology, intelligent diagnosis of Whole Slide Images (WSIs) is essential for automating and objectifying diagnoses, reducing the workload of pathologists. However, diagnostic models often face the challenge of forgetting…

计算机视觉与模式识别 · 计算机科学 2025-03-26 Weixi Zheng , Aoling Huang , Jingping Yuan , Haoyu Zhao , Zhou Zhao , Yongchao Xu , Thierry Géraud

Multiple instance learning (MIL) is a variation of traditional supervised learning problems where data (referred to as bags) are composed of sub-elements (referred to as instances) and only bag labels are available. MIL has a variety of…

机器学习 · 计算机科学 2018-05-02 Han Bao , Tomoya Sakai , Issei Sato , Masashi Sugiyama

Multiple Instance Learning (MIL) effectively analyzes whole slide images but faces overfitting due to attention over-concentration. While existing solutions rely on complex architectural modifications or additional processing steps, we…

计算机视觉与模式识别 · 计算机科学 2025-07-01 Yunlong Zhang , Honglin Li , Yunxuan Sun , Zhongyi Shui , Jingxiong Li , Chenglu Zhu , Lin Yang

We propose probabilistic Shapley inference (PSI), a novel probabilistic framework to model and infer sufficient statistics of feature attributions in flexible predictive models, via latent random variables whose mean recovers Shapley…

机器学习 · 计算机科学 2025-09-09 Mert Ketenci , Iñigo Urteaga , Victor Alfonso Rodriguez , Noémie Elhadad , Adler Perotte

The Shapley value has been proposed as a solution to many applications in machine learning, including for equitable valuation of data. Shapley values are computationally expensive and involve the entire dataset. The query for a point's…

机器学习 · 计算机科学 2022-06-02 Lauren Watson , Rayna Andreeva , Hao-Tsung Yang , Rik Sarkar

Self-supervised learning algorithms (SSL) based on instance discrimination have shown promising results, performing competitively or even outperforming supervised learning counterparts in some downstream tasks. Such approaches employ data…

计算机视觉与模式识别 · 计算机科学 2025-05-01 Mohammad Alkhalefi , Georgios Leontidis , Mingjun Zhong

Weak supervision learning on classification labels has demonstrated high performance in various tasks, while a few pixel-level fine annotations are also affordable. Naturally a question comes to us that whether the combination of…

计算机视觉与模式识别 · 计算机科学 2021-10-26 Jiahui Li , Wen Chen , Xiaodi Huang , Zhiqiang Hu , Qi Duan , Hongsheng Li , Dimitris N. Metaxas , Shaoting Zhang

Multiple instance learning (MIL) has become a standard paradigm for the weakly supervised classification of whole slide images (WSIs). However, this paradigm relies on using a large number of labeled WSIs for training. The lack of training…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Minghao Han , Linhao Qu , Dingkang Yang , Xukun Zhang , Xiaoying Wang , Lihua Zhang

Interpretable machine learning has been focusing on explaining final models that optimize performance. The current state-of-the-art is the Shapley additive explanations (SHAP) that locally explains variable impact on individual predictions,…

Weakly supervised instance segmentation (WSIS) using only image-level labels is a challenging task due to the difficulty of aligning coarse annotations with the finer task. However, with the advancement of deep neural networks (DNNs), WSIS…

计算机视觉与模式识别 · 计算机科学 2024-02-13 Zecheng Li , Zening Zeng , Yuqi Liang , Jin-Gang Yu

The Shapley value provides a principled framework for fairly distributing rewards among participants according to their individual contributions. While prior work has applied this concept to data valuation in machine learning, existing…

计算机科学与博弈论 · 计算机科学 2026-01-22 Zhuofan Jia , Jian Pei

Multiple-instance Learning (MIL) is commonly used to undertake computational pathology (CPath) tasks, and the use of multi-scale patches allows diverse features across scales to be learned. Previous studies using multi-scale features in…

计算机视觉与模式识别 · 计算机科学 2026-02-03 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A Fallowfield , Hakan Bilen , Timothy J Kendall

Instance-level image classification tasks have traditionally relied on single-instance labels to train models, e.g., few-shot learning and transfer learning. However, set-level coarse-grained labels that capture relationships among…

机器学习 · 计算机科学 2023-11-21 Renyu Zhang , Aly A. Khan , Yuxin Chen , Robert L. Grossman

In contrast to the incremental classification task, the incremental detection task is characterized by the presence of data ambiguity, as an image may have differently labeled bounding boxes across multiple continuous learning stages. This…

计算机视觉与模式识别 · 计算机科学 2024-07-10 Ziyue Huang , Yupeng He , Qingjie Liu , Yunhong Wang

Understanding the decision-making process of machine learning models is crucial for ensuring trustworthy machine learning. Data Shapley, a landmark study on data valuation, advances this understanding by assessing the contribution of each…

计算机科学与博弈论 · 计算机科学 2025-01-23 Huaiguang Cai