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When applying multi-instance learning (MIL) to make predictions for bags of instances, the prediction accuracy of an instance often depends on not only the instance itself but also its context in the corresponding bag. From the viewpoint of…

计算机视觉与模式识别 · 计算机科学 2022-04-25 Tiancheng Lin , Hongteng Xu , Canqian Yang , Yi Xu

Multiple instance learning (MIL) is a variation of supervised learning where a single class label is assigned to a bag of instances. In this paper, we state the MIL problem as learning the Bernoulli distribution of the bag label where the…

机器学习 · 计算机科学 2018-06-29 Maximilian Ilse , Jakub M. Tomczak , Max Welling

The multimodal model has demonstrated promise in histopathology. However, most multimodal models are based on H\&E and genomics, adopting increasingly complex yet black-box designs. In our paper, we propose a novel interpretable multimodal…

计算机视觉与模式识别 · 计算机科学 2024-10-03 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

While multiple instance learning (MIL) has shown to be a promising approach for histopathological whole slide image (WSI) analysis, its reliance on permutation invariance significantly limits its capacity to effectively uncover semantic…

图像与视频处理 · 电气工程与系统科学 2025-07-14 Xiwen Chen , Peijie Qiu , Wenhui Zhu , Hao Wang , Huayu Li , Xuanzhao Dong , Xiaotong Sun , Xiaobing Yu , Yalin Wang , Abolfazl Razi , Aristeidis Sotiras

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

图像与视频处理 · 电气工程与系统科学 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

In recent years, the availability of digitized Whole Slide Images (WSIs) has enabled the use of deep learning-based computer vision techniques for automated disease diagnosis. However, WSIs present unique computational and algorithmic…

图像与视频处理 · 电气工程与系统科学 2021-06-15 Yash Sharma , Aman Shrivastava , Lubaina Ehsan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

Fair credit assignment is essential in various machine learning (ML) applications, and Shapley values have emerged as a valuable tool for this purpose. However, in critical ML applications such as data valuation and feature attribution, the…

机器学习 · 计算机科学 2025-03-11 Pranoy Panda , Siddharth Tandon , Vineeth N Balasubramanian

In spite of increased attention on explainable machine learning models, explaining multi-output predictions has not yet been extensively addressed. Methods that use Shapley values to attribute feature contributions to the decision making…

机器学习 · 计算机科学 2023-03-31 Célia Wafa Ayad , Thomas Bonnier , Benjamin Bosch , Jesse Read

In the supervised learning setting termed Multiple-Instance Learning (MIL), the examples are bags of instances, and the bag label is a function of the labels of its instances. Typically, this function is the Boolean OR. The learner observes…

机器学习 · 计算机科学 2015-03-19 Sivan Sabato , Naftali Tishby

Traditional supervised learning tasks require a label for every instance in the training set, but in many real-world applications, labels are only available for collections (bags) of instances. This problem setting, known as multiple…

计算机视觉与模式识别 · 计算机科学 2023-05-23 Georg Wölflein , Lucie Charlotte Magister , Pietro Liò , David J. Harrison , Ognjen Arandjelović

Whole slide images, with their gigapixel-scale panoramas of tissue samples, are pivotal for precise disease diagnosis. However, their analysis is hindered by immense data size and scarce annotations. Existing MIL methods face challenges due…

计算机视觉与模式识别 · 计算机科学 2026-02-26 Weiyi Wu , Xinwen Xu , Chongyang Gao , Xingjian Diao , Siting Li , Jiang Gui

Whole-slide images (WSIs) are an important data modality in computational pathology, yet their gigapixel resolution and lack of fine-grained annotations challenge conventional deep learning models. Multiple instance learning (MIL) offers a…

计算机视觉与模式识别 · 计算机科学 2025-12-22 Qian Zeng , Yihui Wang , Shu Yang , Yingxue Xu , Fengtao Zhou , Jiabo Ma , Dejia Cai , Zhengyu Zhang , Lijuan Qu , Yu Wang , Li Liang , Hao Chen

Shapley values are great analytical tools in game theory to measure the importance of a player in a game. Due to their axiomatic and desirable properties such as efficiency, they have become popular for feature importance analysis in data…

机器学习 · 计算机科学 2020-10-26 Ramin Okhrati , Aldo Lipani

The Shapley Additive Global Importance (SAGE) value is a theoretically appealing interpretability method that fairly attributes global importance to a model's features. However, its exact calculation requires the computation of the…

机器学习 · 统计学 2023-04-07 Christoph Luther , Gunnar König , Moritz Grosse-Wentrup

A growing number of applications, e.g. video surveillance and medical image analysis, require training recognition systems from large amounts of weakly annotated data while some targeted interactions with a domain expert are allowed to…

计算机视觉与模式识别 · 计算机科学 2022-05-10 Marc-André Carbonneau , Eric Granger , Ghyslain Gagnon

Shapley values are widely used for model-agnostic data valuation and feature attribution, yet they implicitly assume contributors are interchangeable. This can be problematic when contributors are dependent (e.g., reused/augmented data or…

机器学习 · 计算机科学 2026-02-11 Kiljae Lee , Ziqi Liu , Weijing Tang , Yuan Zhang

Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

Multiple instance learning (MIL) has emerged as the dominant paradigm for whole slide image (WSI) analysis in computational pathology, achieving strong diagnostic performance through patch-level feature aggregation. However, existing MIL…

计算机视觉与模式识别 · 计算机科学 2025-11-17 Yiran Song , Yikai Zhang , Shuang Zhou , Guojun Xiong , Xiaofeng Yang , Nian Wang , Fenglong Ma , Rui Zhang , Mingquan Lin

Collection of massive well-annotated samples is effective in improving object detection performance but is extremely laborious and costly. Instead of data collection and annotation, the recently proposed Cut-Paste methods [12, 15] show the…

计算机视觉与模式识别 · 计算机科学 2019-07-12 Hao Wang , Qilong Wang , Fan Yang , Weiqi Zhang , Wangmeng Zuo

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

计算机视觉与模式识别 · 计算机科学 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang