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In the causal inference literature an estimator belonging to a class of semi-parametric estimators is called robust if it has desirable properties under the assumption that at least one of the working models is correctly specified. In this…

统计理论 · 数学 2018-06-26 Ingeborg Waernbaum , Laura Pazzagli

Propensity score trimming, which discards subjects with propensity scores below a threshold, is a common way to address positivity violations that complicate causal effect estimation. However, most works on trimming assume treatment is…

统计方法学 · 统计学 2024-07-31 Zach Branson , Edward H. Kennedy , Sivaraman Balakrishnan , Larry Wasserman

The propensity score is widely used for causal inference in observational studies, but common parametric estimators can produce biased and inefficient effect estimates when model assumptions are violated. Nonparametric approaches reduce…

统计方法学 · 统计学 2026-04-09 Maosen Peng , Yan Li , Chong Wu , Liang Li

Causal effect estimation has been studied by many researchers when only observational data is available. Sound and complete algorithms have been developed for pointwise estimation of identifiable causal queries. For non-identifiable causal…

机器学习 · 统计学 2023-06-26 Ziwei Jiang , Lai Wei , Murat Kocaoglu

Observational data have been actively used to estimate treatment effect, driven by the growing availability of electronic health records (EHRs). However, EHRs typically consist of longitudinal records, often introducing time-dependent…

机器学习 · 计算机科学 2024-06-14 Junghwan Lee , Simin Ma , Nicoleta Serban , Shihao Yang

This paper proposes a new method for estimating conditional average treatment effects (CATE) in randomized experiments. We adopt inverse probability weighting (IPW) for identification; however, IPW-transformed outcomes are known to be…

计量经济学 · 经济学 2025-10-14 Mingqian Guan , Komei Fujita , Naoya Sueishi , Shota Yasui

While observational data are routinely used to estimate causal effects of biomedical treatments, doing so requires special methods to adjust for observed confounding. These methods invariably rely on untestable statistical and causal…

统计方法学 · 统计学 2026-03-02 Arman Oganisian

We present a method to analyze sensitivity of frequentist inferences to potential nonignorability of the missingness mechanism. Rather than starting from the selection model, as is typical in such analyses, we assume that the missingness…

统计方法学 · 统计学 2023-02-09 Heng Chen , Daniel F. Heitjan

Making causal inferences from observational studies can be challenging when confounders are missing not at random. In such cases, identifying causal effects is often not guaranteed. Motivated by a real example, we consider a…

统计方法学 · 统计学 2023-10-31 Jian Sun , Bo Fu

The propensity score is a common tool for estimating the causal effect of a binary treatment in observational data. In this setting, matching, subclassification, imputation, or inverse probability weighting on the propensity score can…

统计方法学 · 统计学 2018-01-03 Michael J Lopez , Roee Gutman

Observational studies are often used to understand relationships between exposures and outcomes. They do not, however, allow conclusions about causal relationships to be drawn unless statistical techniques are used to account for the…

统计方法学 · 统计学 2021-07-20 Andreas Markoulidakis , Peter Holmans , Philip Pallmann , Monica Busse , Beth Ann Griffin

Causal inference in observational studies can be challenging when confounders are subject to missingness. Generally, the identification of causal effects is not guaranteed even under restrictive parametric model assumptions when confounders…

统计方法学 · 统计学 2023-03-23 Jian Sun , Bo Fu

Propensity scores are often used for stratification of treatment and control groups of subjects in observational data to remove confounding bias when estimating of causal effect of the treatment on an outcome in so-called potential outcome…

统计理论 · 数学 2018-04-24 Priyantha Wijayatunga

There are many settings where researchers are interested in estimating average treatment effects and are willing to rely on the unconfoundedness assumption, which requires that the treatment assignment be as good as random conditional on…

统计方法学 · 统计学 2018-02-02 Susan Athey , Guido W. Imbens , Stefan Wager

In causal inference, sensitivity models assess how unmeasured confounders could alter causal analyses, but the sensitivity parameter -- which quantifies the degree of unmeasured confounding -- is often difficult to interpret. For this…

统计方法学 · 统计学 2025-09-04 Alec McClean , Zach Branson , Edward H. Kennedy

The comparison of different medical treatments from observational studies or across different clinical studies is often biased by confounding factors such as systematic differences in patient demographics or in the inclusion criteria for…

统计方法学 · 统计学 2025-05-15 Ekkehard Glimm , Lillian Yau

Background: Subgroup analyses are frequently conducted in randomized clinical trials to assess evidence of heterogeneous treatment effect across patient subpopulations. Although randomization balances covariates within subgroups in…

统计方法学 · 统计学 2021-05-27 Siyun Yang , Fan Li , Laine E. Thomas , Fan Li

The idea of "stratified medicine" is an important driver of methodological research on the identification of predictive biomarkers. Most methods proposed so far for this purpose have been developed for the use on randomized data only.…

统计方法学 · 统计学 2022-12-19 Julia Krzykalla , Axel Benner , Annette Kopp-Schneider

Missing data is an universal problem in statistics. We develop a unified framework for estimating parameters defined by general estimating equations under a missing-at-random (MAR) mechanism, based on generalized entropy calibration…

统计方法学 · 统计学 2026-03-31 Mst Moushumi Pervin , Hengfang Wang , Jae Kwang Kim

In causal inference, the Inverse Probability Weighting (IPW) estimator is commonly used to estimate causal effects for estimands within the class of Weighted Average Treatment Effect (WATE). When constructing confidence intervals (CIs),…

统计方法学 · 统计学 2023-12-14 Shunichiro Orihara