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The interest in the extracellular vesicles (EVs) is rapidly growing as they became reliable biomarkers for many diseases. For this reason, fast and accurate techniques of EVs size characterization are the matter of utmost importance. One…

生物物理 · 物理学 2018-03-26 M. Majka , M. Durak-Kozica , A. Kamińska , A. Opalińska , M. Szczęch , E. Stępień

Micelles and vesicles are promising candidates in targeted drug/gene delivery, bioreactors, and templates for nanoparticle synthesis. We investigated the morphology and dynamics of PEG-PDMS-PEG triblock copolymer nano-scale assemblies…

Static Light Scattering (SLS) and Dynamic Light Scattering (DLS) are very important techniques to study the characteristics of nano-particles in dispersion. The data of SLS is determined by the optical characteristic and the measured values…

化学物理 · 物理学 2025-08-11 Yong Sun

The self-assembly of copolymeric vesicles and micelles in micromixers is studied by External Potential Dynamics (EPD) simulations -- a dynamic density functional approach that explicitly accounts for the polymer architecture both at the…

软凝聚态物质 · 物理学 2018-04-10 Simon Kessler , Klaus Drese , Friederike Schmid

In this article we present a new diagnostic approach utilizing flow-cytometry to study compounds of nanoparticle samples in solution by analysis of their scattering patterns retrieved from the cytometric measurements. As a specific…

The author discusses the laser interference method to measure the size of small bio-particles: extracellular vesicles (EVs), exosomes and viruses of nanometer scale in flow cytometry. By introducing a new laser configuration in place of…

仪器与探测器 · 物理学 2021-05-26 T. Shintake

In recent years, extracellular vesicles such have become promising carriers as the next-generation drug delivery platforms. Effective loading of exogenous cargos without compromising the extracellular vesicle membrane is a major challenge.…

生物大分子 · 定量生物学 2023-04-14 Khayrul Islam , Meghdad Razizadeh , Yaling Liu

We present dynamic light scattering (DLS) measurements of soft polymethyl-methacrylate (PMMA) and polyacrylamide(PA) polymer gels prepared with trapped bodies (latex spheres or maghemite nanoparticles). We show that the anomalous…

软凝聚态物质 · 物理学 2015-06-10 Alvaro V. N. C. Teixeira , Erik Geissler , Pedro Licinio

The results obtained using my computing program are consistent with the values obtained twenty years ago. It also makes me believe that how to obtain particle size information using the Light Scattering technique needs to be reconsidered.…

化学物理 · 物理学 2024-06-21 Yong Sun

Super-Resolution Microscopy (SRM) is emerging as a powerful and innovative tool for imaging, characterizing, and understanding the structure of Extracellular Vesicles (EVs). By addressing the need for single-particle analysis with the high…

Extracellular vesicles (EVs) have drawn rapidly increasing attention as the next-generation diagnostic biomarkers and therapeutic agents. However, the heterogeneous nature of EVs necessitates advanced methods for profiling EVs at the…

生物大分子 · 定量生物学 2025-07-08 Yiting Liu , Anthony James El-helou , Bill Soderstrom , Juanfang Ruan , Ying Zhu

DNA self-assembly is a well-understood nanotechnology to obtain extremely ordered structures from the nanometer to up to the hundred of microns scale. By contrast, DNA hydrogels rely on the disordered assembly of DNA building blocks to…

We propose a novel model to obtain the subgrid-scale velocity in the context of large-eddy simulation (LES) of particle-laden turbulent flows, to recover accurate particle statistics. In the new wavelet enrichment model, the subgrid-scale…

流体动力学 · 物理学 2023-10-26 Max Hausmann , Fabien Evrard , Berend van Wachem

Vibrational sum frequency scattering (SFS) has been used to study sub-micron, catanionic vesicles in solution. The vesicles were synthesized from a binary mixture of dodecyltrimethylammonium bromide (DTAB) and sodium dodecylsulfate (SDS)…

软凝聚态物质 · 物理学 2015-03-17 Matthew L. Strader , Hilton Barbosa de Aguiar , Alex G. F. de Beer , Sylvie Roke

Heterogeneous nanoscale particles released by cells known as extracellular vesicles (EVs) are actively investigated for early disease detection1, monitoring2, and advanced therapeutics3. Due to their extremely small size, the stable…

光学 · 物理学 2024-01-26 Chuchuan Hong , Justus C. Ndukaife

Antibodies, disruptive potent therapeutic agents against pharmacological targets, face a barrier crossing immune-system and cellular-membranes. To overcome these, various strategies have been explored including shuttling via liposomes or…

The dynamics of water in electrolyte solutions exhibits a striking, ion-specific anomaly: the diffusion coefficient of water is enhanced relative to the neat liquid in chaotropic CsI solutions, yet suppressed in kosmotropic NaCl solutions.…

化学物理 · 物理学 2026-04-17 Massimo Ciacchi , Ilnur Saitov , Nico Di Fonte , Isabella Daidone , Carlo Pierleoni

Modern laboratory techniques like ultrafast laser excitation and shock compression can bring matter into highly nonequilibrium states with complex structural transformation, metallization and dissociation dynamics. To understand and model…

计算物理 · 物理学 2022-05-24 Qiyu Zeng , Bo Chen , Xiaoxiang Yu , Shen Zhang , Dongdong Kang , Han Wang , Jiayu Dai

Understanding the stability mechanism of surface micro/nanobubbles adhered to gas-evolving electrodes is essential for improving the efficiency of water electrolysis, which is known to be hindered by the bubble coverage on electrodes. Using…

流体动力学 · 物理学 2024-04-16 Yixin Zhang , Xiaojue Zhu , Jeffery A. Wood , Detlef Lohse

Advances in understanding chemical and physical driving forces in self-assembly allow the fabrication of unique nanoarchitectures with subwavelength building blocks as the basis for plasmonic and metamaterial devices. Chemical crosslinking…

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