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Identifying potential drug targets using metabolic modeling requires integrating multiple modeling methods and heterogenous biological datasets, which can be challenging without sophisticated tools. We developed COMO, a user-friendly…

Accurately predicting molecular properties is a challenging but essential task in drug discovery. Recently, many mono-modal deep learning methods have been successfully applied to molecular property prediction. However, the inherent…

机器学习 · 计算机科学 2024-09-16 Xiaohua Lu , Liangxu Xie , Lei Xu , Rongzhi Mao , Shan Chang , Xiaojun Xu

While state-of-the-art models for breast cancer detection leverage multi-view mammograms for enhanced diagnostic accuracy, they often focus solely on visual mammography data. However, radiologists document valuable lesion descriptors that…

计算机视觉与模式识别 · 计算机科学 2024-11-19 Gil Ben-Artzi , Feras Daragma , Shahar Mahpod

The integration of behavioral phenomena into mechanistic models of cognitive function is a fundamental staple of cognitive science. Yet, researchers are beginning to accumulate increasing amounts of data without having the temporal or…

机器学习 · 计算机科学 2021-05-18 Sebastian Musslick

Joint modeling of longitudinal and survival data has become increasingly important in medical research, particularly for understanding disease progression in chronic conditions where both repeated biomarker measurements and time-to-event…

统计方法学 · 统计学 2025-12-30 Nithisha Suryadevara , Vivek Reddy Srigiri

When modeling longitudinal biomedical data, often dimensionality reduction as well as dynamic modeling in the resulting latent representation is needed. This can be achieved by artificial neural networks for dimension reduction, and…

机器学习 · 统计学 2023-12-01 Göran Köber , Raffael Kalisch , Lara Puhlmann , Andrea Chmitorz , Anita Schick , Harald Binder

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

计算机视觉与模式识别 · 计算机科学 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

Protein representation learning is critical for numerous biological tasks. Recently, large transformer-based protein language models (pLMs) pretrained on large scale protein sequences have demonstrated significant success in sequence-based…

机器学习 · 计算机科学 2025-08-12 Xuefeng Liu , Songhao Jiang , Chih-chan Tien , Jinbo Xu , Rick Stevens

Recent studies show that deep learning models achieve good performance on medical imaging tasks such as diagnosis prediction. Among the models, multimodality has been an emerging trend, integrating different forms of data such as chest…

机器学习 · 计算机科学 2022-02-10 Haodi Zhang , Chenyu Xu , Peirou Liang , Ke Duan , Hao Ren , Weibin Cheng , Kaishun Wu

We propose a selective learning method using meta-learning and deep reinforcement learning for medical image interpretation in the setting of limited labeling resources. Our method, MedSelect, consists of a trainable deep learning selector…

计算机视觉与模式识别 · 计算机科学 2021-03-29 Akshay Smit , Damir Vrabac , Yujie He , Andrew Y. Ng , Andrew L. Beam , Pranav Rajpurkar

Clinical information extraction (e.g., 2010 i2b2/VA challenge) usually presents tasks of concept recognition, assertion classification, and relation extraction. Jointly modeling the multi-stage tasks in the clinical domain is an…

计算与语言 · 计算机科学 2026-03-10 Fei Cheng , Ribeka Tanaka , Sadao Kurohashi

Imaging-derived phenotypes (IDPs) summarize multi-organ physiology but provide only static snapshots of diseases that evolve over time. In contrast, longitudinal electronic health records encode disease trajectories through temporal…

Long-tailed distributions in class-imbalanced data present a fundamental challenge for deep learning models, which tend to be biased toward majority classes. While recent methods for long-tailed recognition have mitigated this issue, they…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Heegeon Yoon , Heeyoung Kim

The medical research facilitates to acquire a diverse type of data from the same individual for particular cancer. Recent studies show that utilizing such diverse data results in more accurate predictions. The major challenge faced is how…

基因组学 · 定量生物学 2017-10-11 Jaya Thomas , Lee Sael

One of the most common modes of representing engineering schematics are Piping and Instrumentation diagrams (P&IDs) that describe the layout of an engineering process flow along with the interconnected process equipment. Over the years,…

计算机视觉与模式识别 · 计算机科学 2019-02-01 Rohit Rahul , Shubham Paliwal , Monika Sharma , Lovekesh Vig

This paper introduces an innovative multi-modal fusion deep learning approach to overcome the drawbacks of traditional single-modal recognition techniques. These drawbacks include incomplete information and limited diagnostic accuracy.…

计算机视觉与模式识别 · 计算机科学 2024-06-28 Xiaoyi Liu , Hongjie Qiu , Muqing Li , Zhou Yu , Yutian Yang , Yafeng Yan

In recent several years, the information bottleneck (IB) principle provides an information-theoretic framework for deep multi-view clustering (MVC) by compressing multi-view observations while preserving the relevant information of multiple…

信息论 · 计算机科学 2024-03-26 Xiaoqiang Yan , Zhixiang Jin , Fengshou Han , Yangdong Ye

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

计算机视觉与模式识别 · 计算机科学 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

The recent success of machine learning methods applied to time series collected from Intensive Care Units (ICU) exposes the lack of standardized machine learning benchmarks for developing and comparing such methods. While raw datasets, such…

机器学习 · 计算机科学 2022-01-19 Hugo Yèche , Rita Kuznetsova , Marc Zimmermann , Matthias Hüser , Xinrui Lyu , Martin Faltys , Gunnar Rätsch

Background: Patient recruitment in clinical trials is hindered by complex eligibility criteria and labor-intensive chart reviews. Prior research using text-only models have struggled to address this problem in a reliable and scalable way…

计算与语言 · 计算机科学 2025-03-20 Anatole Callies , Quentin Bodinier , Philippe Ravaud , Kourosh Davarpanah