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Accurate prediction of protein-ligand binding affinity plays a pivotal role in accelerating the discovery of novel drugs and vaccines, particularly for gastrointestinal (GI) diseases such as gastric ulcers, Crohn's disease, and ulcerative…

机器学习 · 计算机科学 2025-11-11 Ziyang Gao , Annie Cheung , Yihao Ou

Microscopic examination of slides prepared from tissue samples is the primary tool for detecting and classifying cancerous lesions, a process that is time-consuming and requires the expertise of experienced pathologists. Recent advances in…

计算机视觉与模式识别 · 计算机科学 2024-10-15 Saba Fatema , Brighton Nuwagira , Sayoni Chakraborty , Reyhan Gedik , Baris Coskunuzer

Deep learning models have gained remarkable performance on a variety of image classification tasks. However, many models suffer from limited performance in clinical or medical settings when data are imbalanced. To address this challenge, we…

图像与视频处理 · 电气工程与系统科学 2022-04-15 Long Gao , Chang Liu , Dooman Arefan , Ashok Panigrahy , Margarita L. Zuley , Shandong Wu

Recent advances in deep learning architectures for sequence modeling have not fully transferred to tasks handling time-series from electronic health records. In particular, in problems related to the Intensive Care Unit (ICU), the…

机器学习 · 计算机科学 2024-02-07 Rita Kuznetsova , Alizée Pace , Manuel Burger , Hugo Yèche , Gunnar Rätsch

Ocular pathology detection from fundus images presents an important challenge on health care. In fact, each pathology has different severity stages that may be deduced by verifying the existence of specific lesions. Each lesion is…

图像与视频处理 · 电气工程与系统科学 2019-05-08 Yaroub Elloumi , Mohamed Akil , Henda Boudegga

Accurate protein structural ensembles can be determined with metainference, a Bayesian inference method that integrates experimental information with prior knowledge of the system and deals with all sources of uncertainty and errors as well…

定量方法 · 定量生物学 2019-01-24 Thomas Löhr , Carlo Camilloni , Massimiliano Bonomi , Michele Vendruscolo

Learning generic and robust feature representations with data from multiple domains for the same problem is of great value, especially for the problems that have multiple datasets but none of them are large enough to provide abundant data…

计算机视觉与模式识别 · 计算机科学 2016-04-27 Tong Xiao , Hongsheng Li , Wanli Ouyang , Xiaogang Wang

We introduce a new dataset, MELINDA, for Multimodal biomEdicaL experImeNt methoD clAssification. The dataset is collected in a fully automated distant supervision manner, where the labels are obtained from an existing curated database, and…

计算与语言 · 计算机科学 2020-12-18 Te-Lin Wu , Shikhar Singh , Sayan Paul , Gully Burns , Nanyun Peng

Blood vessel networks in the brain play a crucial role in stroke research, where understanding their topology is essential for analyzing blood flow dynamics. However, extracting detailed topological vessel network information from…

计算机视觉与模式识别 · 计算机科学 2025-04-17 Joël Mathys , Andreas Plesner , Jorel Elmiger , Roger Wattenhofer

We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

图像与视频处理 · 电气工程与系统科学 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

Biomedical information extraction (BioIE) is important to many applications, including clinical decision support, integrative biology, and pharmacovigilance, and therefore it has been an active research. Unlike existing reviews covering a…

计算与语言 · 计算机科学 2016-06-28 Feifan Liu , Jinying Chen , Abhyuday Jagannatha , Hong Yu

TalkBank is an online database that facilitates the sharing of linguistics research data. However, the existing TalkBank's API has limited data filtering and batch processing capabilities. To overcome these limitations, this paper…

数据库 · 计算机科学 2023-06-23 Man Ho Wong

Deep learning-based segmentation and classification are crucial to large-scale biomedical imaging, particularly for 3D data, where manual analysis is impractical. Although many methods exist, selecting suitable models and tuning parameters…

In the field of computational pathology, the use of decision support systems powered by state-of-the-art deep learning solutions has been hampered by the lack of large labeled datasets. Until recently, studies relied on datasets in the…

计算机视觉与模式识别 · 计算机科学 2018-10-01 Gabriele Campanella , Vitor Werneck Krauss Silva , Thomas J. Fuchs

Edge deep learning, a paradigm change reconciling edge computing and deep learning, facilitates real-time decision making attuned to environmental factors through the close integration of computational resources and data sources. Here we…

计算机视觉与模式识别 · 计算机科学 2026-05-11 Yiwen Xu , Tariq M. Khan , Yang Song , Erik Meijering

Survival analysis is central to clinical research, informing patient prognoses, guiding treatment decisions, and optimising resource allocation. Accurate time-to-event predictions not only improve quality of life but also reveal risk…

In recent years a vast amount of visual content has been generated and shared from many fields, such as social media platforms, medical imaging, and robotics. This abundance of content creation and sharing has introduced new challenges,…

计算机视觉与模式识别 · 计算机科学 2022-11-01 Wei Chen , Yu Liu , Weiping Wang , Erwin Bakker , Theodoros Georgiou , Paul Fieguth , Li Liu , Michael S. Lew

Diabetes is a global raising pandemic. Diabetes patients are at risk of developing foot ulcer that usually leads to limb amputation. In order to develop a self monitoring mobile application, in this work, we propose a novel deep subspace…

图像与视频处理 · 电气工程与系统科学 2021-10-06 Azadeh Alavi

Deep learning techniques hold immense promise for advancing medical image analysis, particularly in tasks like image segmentation, where precise annotation of regions or volumes of interest within medical images is crucial but manually…

In tissue characterization and cancer diagnostics, multimodal imaging has emerged as a powerful technique. Thanks to computational advances, large datasets can be exploited to discover patterns in pathologies and improve diagnosis. However,…

计算机视觉与模式识别 · 计算机科学 2023-03-21 Eva Breznik , Elisabeth Wetzer , Joakim Lindblad , Nataša Sladoje