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Cancer diagnosis, prognosis, and therapy response predictions from tissue specimens highly depend on the phenotype and topological distribution of constituting histological entities. Thus, adequate tissue representations for encoding…

Graph-level representations are crucial tools for characterising structural differences between graphs. However, comparing graphs with different cardinalities, even when sampled from the same underlying distribution, remains challenging.…

机器学习 · 计算机科学 2026-05-08 Katharina Limbeck , Nadja Häusermann , Martin Carrasco , Guy Wolf , Bastian Rieck

Precise segmentation and classification of cell instances are vital for analyzing the tissue microenvironment in histology images, supporting medical diagnosis, prognosis, treatment planning, and studies of brain cytoarchitecture. However,…

计算机视觉与模式识别 · 计算机科学 2025-02-14 Valentina Vadori , Jean-Marie Graïc , Antonella Peruffo , Livio Finos , Ujwala Kiran Chaudhari , Enrico Grisan

Brain networks are typically represented by adjacency matrices, where each node corresponds to a brain region. In traditional brain network analysis, nodes are assumed to be matched across individuals, but the methods used for node matching…

统计方法学 · 统计学 2025-03-21 Martin Cole , Yang Xiang , Will Consagra , Anuj Srivastava , Xing Qiu , Zhengwu Zhang

Graph kernels have been successfully applied to many graph classification problems. Typically, a kernel is first designed, and then an SVM classifier is trained based on the features defined implicitly by this kernel. This two-stage…

Deep learning architectures based on convolutional neural networks tend to rely on continuous, smooth features. While this characteristics provides significant robustness and proves useful in many real-world tasks, it is strikingly…

计算机视觉与模式识别 · 计算机科学 2026-03-10 Zuzanna Buchnajzer , Kacper Dobek , Stanisław Hapke , Daniel Jankowski , Krzysztof Krawiec

Community detection algorithms have been widely used to study the organization of complex systems like the brain. A principal appeal of these techniques is their ability to identify a partition of brain regions (or nodes) into communities,…

神经元与认知 · 定量生物学 2017-04-20 Arian Ashourvan , Qawi K. Telesford , Timothy Verstynen , Jean M. Vettel , Danielle S. Bassett

A central idea in understanding brains and building artificial intelligence is that structure determines function. Yet, how the brain's complex structure arises from a limited set of genetic instructions remains a key question. The ultra…

神经元与认知 · 定量生物学 2026-01-28 Xingyu Liu , Yubin Li , Guozhang Chen

Deep learning (DL) has arguably emerged as the method of choice for the detection and segmentation of biological structures in microscopy images. However, DL typically needs copious amounts of annotated training data that is for biomedical…

图像与视频处理 · 电气工程与系统科学 2020-03-20 Mangal Prakash , Tim-Oliver Buchholz , Manan Lalit , Pavel Tomancak , Florian Jug , Alexander Krull

Graph embedding is a powerful method to represent graph neurological data (e.g., brain connectomes) in a low dimensional space for brain connectivity mapping, prediction and classification. However, existing embedding algorithms have two…

计算机视觉与模式识别 · 计算机科学 2020-09-25 Alin Banka , Inis Buzi , Islem Rekik

Converging evidence suggests that the mammalian ventral visual pathway encodes increasingly complex stimulus features in downstream areas. Using deep convolutional neural networks, we can now quantitatively demonstrate that there is indeed…

神经元与认知 · 定量生物学 2017-03-13 Umut Güçlü , Marcel A. J. van Gerven

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

图像与视频处理 · 电气工程与系统科学 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

Inspired by the impressive success of contrastive learning (CL), a variety of graph augmentation strategies have been employed to learn node representations in a self-supervised manner. Existing methods construct the contrastive samples by…

机器学习 · 计算机科学 2022-12-14 Peiyao Zhao , Yuangang Pan , Xin Li , Xu Chen , Ivor W. Tsang , Lejian Liao

Automatic detection of abnormal cervical cells from Thinprep Cytologic Test (TCT) images is a critical component in the development of intelligent computer-aided diagnostic systems. However, existing algorithms typically fail to effectively…

计算机视觉与模式识别 · 计算机科学 2025-08-25 Jincheng Li , Danyang Dong , Menglin Zheng , Jingbo Zhang , Yueqin Hang , Lichi Zhang , Lili Zhao

We propose a method for gene expression based analysis of cancer phenotypes incorporating network biology knowledge through unsupervised construction of computational graphs. The structural construction of the computational graphs is driven…

We present graph attention networks (GATs), novel neural network architectures that operate on graph-structured data, leveraging masked self-attentional layers to address the shortcomings of prior methods based on graph convolutions or…

Unsupervised graph representation learning aims to learn low-dimensional node embeddings without supervision while preserving graph topological structures and node attributive features. Previous graph neural networks (GNN) require a large…

机器学习 · 计算机科学 2020-09-04 Yanqiao Zhu , Yichen Xu , Feng Yu , Shu Wu , Liang Wang

Graph convolutional networks are a new promising learning approach to deal with data on irregular domains. They are predestined to overcome certain limitations of conventional grid-based architectures and will enable efficient handling of…

计算机视觉与模式识别 · 计算机科学 2018-09-17 Lasse Hansen , Jasper Diesel , Mattias P. Heinrich

Deep convolutional neural networks (DCNNs) have become the state-of-the-art computational models of biological object recognition. Their remarkable success has helped vision science break new ground and recent efforts have started to…

计算机视觉与模式识别 · 计算机科学 2023-08-22 Leonard E. van Dyck , Walter R. Gruber

Deep graph embedding is an important approach for community discovery. Deep graph neural network with self-supervised mechanism can obtain the low-dimensional embedding vectors of nodes from unlabeled and unstructured graph data. The…

社会与信息网络 · 计算机科学 2021-02-09 Shuliang Xu , Shenglan Liu , Lin Feng