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For effective treatment of Alzheimer disease (AD), it is important to identify subjects who are most likely to exhibit rapid cognitive decline. Herein, we developed a novel framework based on a deep convolutional neural network which can…

计算机视觉与模式识别 · 计算机科学 2017-04-21 Hongyoon Choi , Kyong Hwan Jin

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

图像与视频处理 · 电气工程与系统科学 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Photoplethysmography (PPG) signals, typically acquired from wearable devices, hold significant potential for continuous fitness-health monitoring. In particular, heart conditions that manifest in rare and subtle deviating heart patterns may…

机器学习 · 计算机科学 2023-07-14 Ramin Ghorbani , Marcel J. T. Reinders , David M. J. Tax

Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially…

Deep generative models have emerged as promising tools for detecting arbitrary anomalies in data, dispensing with the necessity for manual labelling. Recently, autoregressive transformers have achieved state-of-the-art performance for…

Automated anomaly detection from medical images, such as MRIs and X-rays, can significantly reduce human effort in disease diagnosis. Owing to the complexity of modeling anomalies and the high cost of manual annotation by domain experts…

图像与视频处理 · 电气工程与系统科学 2022-09-07 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd Schwedt , Baoxin Li

Many important data analysis applications present with severely imbalanced datasets with respect to the target variable. A typical example is medical image analysis, where positive samples are scarce, while performance is commonly estimated…

机器学习 · 计算机科学 2018-11-05 Nazly Rocio Santos Buitrago , Loek Tonnaer , Vlado Menkovski , Dimitrios Mavroeidis

Fraud in healthcare is widespread, as doctors could prescribe unnecessary treatments to increase bills. Insurance companies want to detect these anomalous fraudulent bills and reduce their losses. Traditional fraud detection methods use…

机器学习 · 计算机科学 2020-10-13 Victoria Snorovikhina , Alexey Zaytsev

Recent studies suggest that combined analysis of Magnetic resonance imaging~(MRI) that measures brain atrophy and positron emission tomography~(PET) that quantifies hypo-metabolism provides improved accuracy in diagnosing Alzheimer's…

计算机视觉与模式识别 · 计算机科学 2018-07-31 Apoorva Sikka , Skand Vishwanath Peri , Deepti. R. Bathula

Automated surface inspection is an important task in many manufacturing industries and often requires machine learning driven solutions. Supervised approaches, however, can be challenging, since it is often difficult to obtain large amounts…

计算机视觉与模式识别 · 计算机科学 2018-11-19 Matthias Haselmann , Dieter P. Gruber , Paul Tabatabai

Although mainstream unsupervised anomaly detection (AD) algorithms perform well in academic datasets, their performance is limited in practical application due to the ideal experimental setting of clean training data. Training with noisy…

计算机视觉与模式识别 · 计算机科学 2024-03-22 Xi Jiang , Ying Chen , Qiang Nie , Yong Liu , Jianlin Liu , Bin-Bin Gao , Jun Liu , Chengjie Wang , Feng Zheng

Early detection of Alzheimer disease is crucial for deploying interventions and slowing the disease progression. A lot of machine learning and deep learning algorithms have been explored in the past decade with the aim of building an…

图像与视频处理 · 电气工程与系统科学 2022-09-26 Narotam Singh , Patteshwari. D , Neha Soni , Amita Kapoor

Structural MRI and PET imaging play an important role in the diagnosis of Alzheimer's disease (AD), showing the morphological changes and glucose metabolism changes in the brain respectively. The manifestations in the brain image of some…

图像与视频处理 · 电气工程与系统科学 2023-08-11 Yanteng Zhang , Qizhi Teng , Xiaohai He , Tong Niu , Lipei Zhang , Yan Liu , Chao Ren

Minimizing the need for pixel-level annotated data to train PET lesion detection and segmentation networks is highly desired and can be transformative, given time and cost constraints associated with expert annotations. Current unsupervised…

图像与视频处理 · 电气工程与系统科学 2025-09-18 Shadab Ahamed , Arman Rahmim

So-called unsupervised anomaly detection is better described as semi-supervised, as it assumes all training data are nominal. This assumption simplifies training but requires manual data curation, introducing bias and limiting adaptability.…

计算机视觉与模式识别 · 计算机科学 2025-10-29 Muhammad Aqeel , Shakiba Sharifi , Marco Cristani , Francesco Setti

Ultrasonography is an essential tool in mid-pregnancy for assessing fetal development, appreciated for its non-invasive and real-time imaging capabilities. Yet, the interpretation of ultrasound images is often complicated by acoustic…

图像与视频处理 · 电气工程与系统科学 2024-07-23 Hanna Mykula , Lisa Gasser , Silvia Lobmaier , Julia A. Schnabel , Veronika Zimmer , Cosmin I. Bercea

Segmentation masks of pathological areas are useful in many medical applications, such as brain tumour and stroke management. Moreover, healthy counterfactuals of diseased images can be used to enhance radiologists' training files and to…

图像与视频处理 · 电气工程与系统科学 2024-10-02 Alessandro Fontanella , Grant Mair , Joanna Wardlaw , Emanuele Trucco , Amos Storkey

The accurate diagnosis of Alzheimer's disease (AD) and prognosis of mild cognitive impairment (MCI) conversion are crucial for early intervention. However, existing multimodal methods face several challenges, from the heterogeneity of input…

机器学习 · 计算机科学 2025-03-20 Chenyu Liu , Luca Rossi

The challenges of collecting medical data on neurological disorder diagnosis problems paved the way for learning methods with scarce number of samples. Due to this reason, one-shot learning still remains one of the most challenging and…

神经元与认知 · 定量生物学 2022-12-16 Oben Özgür , Arwa Rekik , Islem Rekik

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

机器学习 · 计算机科学 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil