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Brain metastases affect approximately between 20% and 40% of cancer patients and are commonly treated with radiotherapy or radiosurgery. Early prediction of recurrence following treatment could enable timely clinical intervention and…

图像与视频处理 · 电气工程与系统科学 2025-12-18 Ines Faria , Matheus Silva , Crystian Saraiva , Jose Soares , Victor Alves

Establishing the reproducibility of radiomic signatures is a critical step in the path to clinical adoption of quantitative imaging biomarkers; however, radiomic signatures must also be meaningfully related to an outcome of clinical…

Radiomics aims to extract and analyze large numbers of quantitative features from medical images and is highly promising in staging, diagnosing, and predicting outcomes of cancer treatments. Nevertheless, several challenges need to be…

机器学习 · 计算机科学 2017-10-09 Zhiguo Zhou , Zhi-Jie Zhou , Hongxia Hao , Shulong Li , Xi Chen , You Zhang , Michael Folkert , Jing Wang

Artificial intelligence (AI) enabled radiomics has evolved immensely especially in the field of oncology. Radiomics provide assistancein diagnosis of cancer, planning of treatment strategy, and predictionof survival. Radiomics in…

图像与视频处理 · 电气工程与系统科学 2019-10-17 Syed Muhammad Anwar , Tooba Altaf , Khola Rafique , Harish RaviPrakash , Hassan Mohy-ud-Din , Ulas Bagci

Artificial intelligence (AI) techniques have significant potential to enable effective, robust and automated image phenotyping including identification of subtle patterns. AI-based detection searches the image space to find the regions of…

医学物理 · 物理学 2022-01-17 Fereshteh Yousefirizi , Pierre Decazes , Amine Amyar , Su Ruan , Babak Saboury , Arman Rahmim

Tongue squamous cell carcinoma (TSCC) is an aggressive malignancy with marked biological heterogeneity and variable clinical outcomes. Although molecular profiling has improved understanding of TSCC heterogeneity, its clinical use remains…

Individual cancer cells carry a bewildering number of distinct genomic alterations i.e., copy number variations and mutations, making it a challenge to uncover genomic-driven mechanisms governing tumorigenesis. Here we performed…

Semantic image synthesis (SIS) aims to generate realistic images that match given semantic masks. Despite recent advances allowing high-quality results and precise spatial control, they require a massive semantic segmentation dataset for…

计算机视觉与模式识别 · 计算机科学 2024-02-23 Jungwoo Chae , Hyunin Cho , Sooyeon Go , Kyungmook Choi , Youngjung Uh

Novel multimodal imaging methods are capable of generating extensive, super high resolution datasets for preclinical research. Yet, a massive lack of annotations prevents the broad use of deep learning to analyze such data. So far, existing…

图像与视频处理 · 电气工程与系统科学 2021-04-26 Izabela Horvath , Johannes C. Paetzold , Oliver Schoppe , Rami Al-Maskari , Ivan Ezhov , Suprosanna Shit , Hongwei Li , Ali Ertuerk , Bjoern H. Menze

Robust and generalizable segmentation of brain tumors on multi-parametric magnetic resonance imaging (MRI) remains difficult because tumor types differ widely. The BraTS 2025 Lighthouse Challenge benchmarks segmentation methods on diverse…

The tumor microenvironment (TME) significantly impacts cancer prognosis due to its immune composition. While therapies for altering the immune composition, including immunotherapies, have shown exciting results for treating hematological…

定量方法 · 定量生物学 2023-10-17 Zitong Jerry Wang , Alexander M. Xu , Aman Bhargava , Matt W. Thomson

We present a new Randomized Multiple Independent Comb Shaping (RandoMICS) algorithm based on phase-only tailored transmission for ultrashort laser pulse replication. The benefit of this method is satellite-free generation of programmable…

光学 · 物理学 2020-11-02 Konstantin Yushkov , Vladimir Molchanov

Objective. Standard Magnetic Resonance Imaging (MRI) reconstruction pipelines discard phase information captured during acquisition, despite evidence that it encodes tissue properties relevant to tumor diagnosis. Current machine learning…

图像与视频处理 · 电气工程与系统科学 2026-04-17 Marco Schlimbach , Moritz Rempe , Jessica Mnischek , Lukas T. Rotkopf , Jens Weingarten , Jens Kleesiek , Kevin Kröninger

We demonstrate the power of the genetic algorithms to construct the cellular automata model simulating the growth of 2-dimensional close-to-circular clusters revealing the desired properties, such as the growth rate and, at the same time,…

细胞行为 · 定量生物学 2009-11-13 Branislav Brutovsky , Denis Horvath , Vladimir Lisy

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

图像与视频处理 · 电气工程与系统科学 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Machine-based brain tumor segmentation can help doctors make better diagnoses. However, the complex structure of brain tumors and expensive pixel-level annotations present challenges for automatic tumor segmentation. In this paper, we…

计算机视觉与模式识别 · 计算机科学 2024-08-05 Ruitao Xie , Limai Jiang , Xiaoxi He , Yi Pan , Yunpeng Cai

Neuroblastoma is one of the most common cancers in infants, and the initial diagnosis of this disease is difficult. At present, the MYCN gene amplification (MNA) status is detected by invasive pathological examination of tumor samples. This…

图像与视频处理 · 电气工程与系统科学 2022-05-24 Zihan Zhang , Xiang Xiang , Xuehua Peng , Jianbo Shao

Recent advances in Diffusion Probabilistic Models (DPMs) have set new standards in high-quality image synthesis. Yet, controlled generation remains challenging, particularly in sensitive areas such as medical imaging. Medical images feature…

计算机视觉与模式识别 · 计算机科学 2025-10-09 Sarah Cechnicka , Matthew Baugh , Weitong Zhang , Mischa Dombrowski , Zhe Li , Johannes C. Paetzold , Candice Roufosse , Bernhard Kainz

Cancer pathology is unique to a given individual, and developing personalized diagnostic and treatment protocols are a primary concern. Mathematical modeling and simulation is a promising approach to personalized cancer medicine. Yet, the…

组织与器官 · 定量生物学 2020-08-03 Alvaro Köhn-Luque , Xiaoran Lai , Arnoldo Frigessi

While lung cancer is the second most diagnosed form of cancer in men and women, a sufficiently early diagnosis can be pivotal in patient survival rates. Imaging-based, or radiomics-driven, detection methods have been developed to aid…

神经与进化计算 · 计算机科学 2017-10-23 Mohammad Javad Shafiee , Audrey G. Chung , Farzad Khalvati , Masoom A. Haider , Alexander Wong