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Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Multiple Instance Learning (MIL) gains popularity in many real-life machine learning applications due to its weakly supervised nature. However, the corresponding effort on explaining MIL lags behind, and it is usually limited to presenting…

In partial multi-label learning (PML), each data example is equipped with a candidate label set, which consists of multiple ground-truth labels and other false-positive labels. Recently, graph-based methods, which demonstrate a good ability…

机器学习 · 计算机科学 2023-05-11 Haobo Wang , Shisong Yang , Gengyu Lyu , Weiwei Liu , Tianlei Hu , Ke Chen , Songhe Feng , Gang Chen

Although significant progress achieved, multi-label classification is still challenging due to the complexity of correlations among different labels. Furthermore, modeling the relationships between input and some (dull) classes further…

计算机视觉与模式识别 · 计算机科学 2020-08-18 Junbing Li , Changqing Zhang , Pengfei Zhu , Baoyuan Wu , Lei Chen , Qinghua Hu

Multilabel classification is a relatively recent subfield of machine learning. Unlike to the classical approach, where instances are labeled with only one category, in multilabel classification, an arbitrary number of categories is chosen…

人工智能 · 计算机科学 2013-03-01 Alfonso E. Romero , Luis M. de Campos

Multi-Instance Learning (MIL) has shown impressive performance for histopathology whole slide image (WSI) analysis using bags or pseudo-bags. It involves instance sampling, feature representation, and decision-making. However, existing…

计算机视觉与模式识别 · 计算机科学 2024-03-14 Tingting Zheng , Kui Jiang , Hongxun Yao

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

计算机视觉与模式识别 · 计算机科学 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

In this paper, we investigate the use of an unsupervised label clustering technique and demonstrate that it enables substantial improvements in visual relationship prediction accuracy on the Person in Context (PIC) dataset. We propose to…

计算机视觉与模式识别 · 计算机科学 2018-09-11 Hsuan-Kung Yang , An-Chieh Cheng , Kuan-Wei Ho , Tsu-Jui Fu , Chun-Yi Lee

Classification of gigapixel Whole Slide Images (WSIs) is an important prediction task in the emerging area of computational pathology. There has been a surge of research in deep learning models for WSI classification with clinical…

计算机视觉与模式识别 · 计算机科学 2023-05-04 Sajid Javed , Arif Mahmood , Talha Qaiser , Naoufel Werghi , Nasir Rajpoot

In this paper, we propose an instance similarity learning (ISL) method for unsupervised feature representation. Conventional methods assign close instance pairs in the feature space with high similarity, which usually leads to wrong…

计算机视觉与模式识别 · 计算机科学 2021-08-06 Ziwei Wang , Yunsong Wang , Ziyi Wu , Jiwen Lu , Jie Zhou

This paper proposes an Incremental Learning (IL) approach to enhance the accuracy and efficiency of deep learning models in analyzing T2-weighted (T2w) MRI medical images prostate cancer detection using the PI-CAI dataset. We used multiple…

计算机视觉与模式识别 · 计算机科学 2025-04-29 Sara Yavari , Jacob Furst

We describe a novel weakly supervised deep learning framework that combines both the discriminative and generative models to learn meaningful representation in the multiple instance learning (MIL) setting. MIL is a weakly supervised…

机器学习 · 计算机科学 2018-07-09 Shabnam Ghaffarzadegan

Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images…

计算机视觉与模式识别 · 计算机科学 2025-11-20 Xiangde Luo , Jinxi Xiang , Yuanfeng Ji , Ruijiang Li

Multiple instance learning (MIL) has shown significant promise in histopathology whole slide image (WSI) analysis for cancer diagnosis and prognosis. However, the inherent spatial heterogeneity of WSIs presents critical challenges, as…

计算机视觉与模式识别 · 计算机科学 2026-01-13 Junjian Li , Jin Liu , Hulin Kuang , Hailin Yue , Mengshen He , Jianxin Wang

Whole Slide Image (WSI) analysis is a powerful method to facilitate the diagnosis of cancer in tissue samples. Automating this diagnosis poses various issues, most notably caused by the immense image resolution and limited annotations. WSIs…

计算机视觉与模式识别 · 计算机科学 2023-04-19 Ahmet Gokberk Gul , Oezdemir Cetin , Christoph Reich , Tim Prangemeier , Nadine Flinner , Heinz Koeppl

In this paper, we propose an extension to an existing algorithm (instance-MIR) which tackles the multiple instance regression (MIR) problem, also known as distribution regression. The MIR setting arises when the data is a collection of…

机器学习 · 统计学 2019-08-20 Thomas Uriot

Multiple-instance learning (MIL) has served as an important tool for a wide range of vision applications, for instance, image classification, object detection, and visual tracking. In this paper, we propose a novel method to solve the…

计算机视觉与模式识别 · 计算机科学 2015-10-06 Xinggang Wang , Zhuotun Zhu , Cong Yao , Xiang Bai

Partial label learning (PLL) is a typical weakly supervised learning problem, where each training example is associated with a set of candidate labels among which only one is true. Most existing PLL approaches assume that the incorrect…

机器学习 · 计算机科学 2021-10-27 Ning Xu , Congyu Qiao , Xin Geng , Min-Ling Zhang

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

计算机视觉与模式识别 · 计算机科学 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman

Whole slide images, with their gigapixel-scale panoramas of tissue samples, are pivotal for precise disease diagnosis. However, their analysis is hindered by immense data size and scarce annotations. Existing MIL methods face challenges due…

计算机视觉与模式识别 · 计算机科学 2026-02-26 Weiyi Wu , Xinwen Xu , Chongyang Gao , Xingjian Diao , Siting Li , Jiang Gui