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Accurately predicting the time of occurrence of an event of interest is a critical problem in longitudinal data analysis. One of the main challenges in this context is the presence of instances whose event outcomes become unobservable after…

机器学习 · 计算机科学 2017-12-26 Ping Wang , Yan Li , Chandan K. Reddy

Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

机器学习 · 计算机科学 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell

In recurrent survival analysis where the event of interest can occur multiple times for each subject, frailty models play a crucial role by capturing unobserved heterogeneity at the subject level within a population. Frailty models…

统计方法学 · 统计学 2024-10-30 Borna Bateni , Peyman Bateni , Bishwadeep Bhattacharyya , Devin Reeh

An every increasing number of clinical trials features a time-to-event outcome and records non-tabular patient data, such as magnetic resonance imaging or text data in the form of electronic health records. Recently, several neural-network…

机器学习 · 计算机科学 2022-10-24 Gabriele Campanella , Lucas Kook , Ida Häggström , Torsten Hothorn , Thomas J. Fuchs

Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not capitalize on the…

Predicting the incidence of complex chronic conditions such as heart failure is challenging. Deep learning models applied to rich electronic health records may improve prediction but remain unexplainable hampering their wider use in medical…

We propose a novel deep learning approach to nonparametric statistical inference for the conditional hazard function of survival time with right-censored data. We use a deep neural network (DNN) to approximate the logarithm of a conditional…

统计方法学 · 统计学 2024-10-24 Wen Su , Kin-Yat Liu , Guosheng Yin , Jian Huang , Xingqiu Zhao

The COVID-19 pandemic has had a considerable impact on day-to-day life. Tackling the disease by providing the necessary resources to the affected is of paramount importance. However, estimation of the required resources is not a trivial…

图像与视频处理 · 电气工程与系统科学 2022-05-11 Sai Vidyaranya Nuthalapati , Marcela Vizcaychipi , Pallav Shah , Piotr Chudzik , Chee Hau Leow , Paria Yousefi , Ahmed Selim , Keiran Tait , Ben Irving

Survival analysis is a critical tool for modeling time-to-event data. Recent deep learning-based models have reduced various modeling assumptions including proportional hazard and linearity. However, a persistent challenge remains in…

机器学习 · 计算机科学 2025-12-30 Maxmillan Ries , Sohan Seth

Methods: We developed a self-supervised deep learning model that extracts meaningful patterns from multi-modal signals (Electroencephalography (EEG), Electrocardiography (ECG), and respiratory signals). The model was trained on data from…

机器学习 · 计算机科学 2025-07-15 Zhengxiao He , Huayu Li , Geng Yuan , William D. S. Killgore , Stuart F. Quan , Chen X. Chen , Ao Li

Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and…

机器学习 · 计算机科学 2026-03-13 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Muddassar Farooq

Survival analysis serves as a fundamental component in numerous healthcare applications, where the determination of the time to specific events (such as the onset of a certain disease or death) for patients is crucial for clinical…

Estimating the causal effect of time-varying treatments on survival outcomes is a challenging task in many domains, particularly in medicine where treatment protocols adapt over time. While recent advances in representation learning have…

机器学习 · 统计学 2025-05-06 Ayoub Abraich

Survival prediction of cancers is crucial for clinical practice, as it informs mortality risks and influences treatment plans. However, a static model trained on a single dataset fails to adapt to the dynamically evolving clinical…

机器学习 · 计算机科学 2026-01-21 Dianzhi Yu , Conghao Xiong , Yankai Chen , Wenqian Cui , Xinni Zhang , Yifei Zhang , Hao Chen , Joseph J. Y. Sung , Irwin King

Seizure forecasting may provide patients with timely warnings to adapt their daily activities and help clinicians deliver more objective, personalized treatments. While recent work has convincingly demonstrated that seizure risk assessment…

神经元与认知 · 定量生物学 2019-06-10 Christian Meisel , Rima El Atrache , Michele Jackson , Sarah Schubach , Claire Ufongene , Tobias Loddenkemper

Survival analysis plays a crucial role in estimating the likelihood of future events for patients by modeling time-to-event data, particularly in healthcare settings where predictions about outcomes such as death and disease recurrence are…

机器学习 · 计算机科学 2024-10-01 Muhammad Ridzuan , Numan Saeed , Fadillah Adamsyah Maani , Karthik Nandakumar , Mohammad Yaqub

Most existing time-to-event methods focus on either single-event or competing-risks settings, leaving multi-event scenarios relatively underexplored. In many healthcare applications, for example, a patient may experience multiple clinical…

Time-to-event analysis is an important statistical tool for allocating clinical resources such as ICU beds. However, classical techniques like the Cox model cannot directly incorporate images due to their high dimensionality. We propose a…

图像与视频处理 · 电气工程与系统科学 2021-08-24 Michelle Shu , Richard Strong Bowen , Charles Herrmann , Gengmo Qi , Michele Santacatterina , Ramin Zabih

The influx of deep learning (DL) techniques into the field of survival analysis in recent years has led to substantial methodological progress; for instance, learning from unstructured or high-dimensional data such as images, text or omics…

机器学习 · 统计学 2024-02-23 Simon Wiegrebe , Philipp Kopper , Raphael Sonabend , Bernd Bischl , Andreas Bender

To improve the performance of Intensive Care Units (ICUs), the field of bio-statistics has developed scores which try to predict the likelihood of negative outcomes. These help evaluate the effectiveness of treatments and clinical practice,…

机器学习 · 计算机科学 2019-08-23 William Caicedo-Torres , Jairo Gutierrez