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Controlled feature selection aims to discover the features a response depends on while limiting the false discovery rate (FDR) to a predefined level. Recently, multiple deep-learning-based methods have been proposed to perform controlled…

机器学习 · 统计学 2022-10-24 Derek Hansen , Brian Manzo , Jeffrey Regier

It is a common saying that testing for conditional independence, i.e., testing whether whether two random vectors $X$ and $Y$ are independent, given $Z$, is a hard statistical problem if $Z$ is a continuous random variable (or vector). In…

统计理论 · 数学 2022-03-25 Rajen D. Shah , Jonas Peters

Semiparametric accelerated failure time (AFT) models directly relate the predicted failure times to covariates and are a useful alternative to models that work on the hazard function or the survival function. For case-cohort data, much less…

统计计算 · 统计学 2022-12-15 Steven Chiou , Sangwook Kang , Jun Yan

One limitation of the most statistical/machine learning-based variable selection approaches is their inability to control the false selections. A recently introduced framework, model-x knockoffs, provides that to a wide range of models but…

机器学习 · 统计学 2025-09-03 Deniz Koyuncu , Alex Gittens , Bülent Yener

Statistical dependence measures like mutual information is ideal for analyzing autoencoders, but it can be ill-posed for deterministic, static, noise-free networks. We adopt the variational (Gaussian) formulation that makes dependence among…

机器学习 · 计算机科学 2026-03-24 Bo Hu , Jose C Principe

Large case/control Genome-Wide Association Studies (GWAS) often include groups of related individuals with known relationships. When testing for associations at a given locus, current methods incorporate only the familial relationships…

应用统计 · 统计学 2014-08-01 Joshua N. Sampson , Bill Wheeler , Peng Li , Jianxin Shi

External controls from historical trials or observational data can augment randomized controlled trials when large-scale randomization is impractical or unethical, such as in drug evaluation for rare diseases. However, non-randomized…

统计方法学 · 统计学 2025-05-08 Ke Zhu , Shu Yang , Xiaofei Wang

Constraint-based causal discovery algorithms utilize many statistical tests for conditional independence to uncover networks of causal dependencies. These approaches to causal discovery rely on an assumed correspondence between the…

机器学习 · 计算机科学 2025-04-18 Bijan Mazaheri , Jiaqi Zhang , Caroline Uhler

In a case-control study aimed at locating autosomal disease variants for a disease of interest, association between markers and the disease status is often tested by comparing the marker minor allele frequencies (MAFs) between cases and…

应用统计 · 统计学 2020-02-13 Marianne A. Jonker , Jakub Pecanka

Model-X knockoffs allows analysts to perform feature selection using almost any machine learning algorithm while still provably controlling the expected proportion of false discoveries. To apply model-X knockoffs, one must construct…

统计方法学 · 统计学 2021-06-30 Asher Spector , Lucas Janson

This paper introduces a machine for sampling approximate model-X knockoffs for arbitrary and unspecified data distributions using deep generative models. The main idea is to iteratively refine a knockoff sampling mechanism until a criterion…

统计方法学 · 统计学 2020-03-03 Yaniv Romano , Matteo Sesia , Emmanuel J. Candès

Feature selection prepares the AI-readiness of data by eliminating redundant features. Prior research falls into two primary categories: i) Supervised Feature Selection, which identifies the optimal feature subset based on their relevance…

机器学习 · 计算机科学 2024-03-08 Xinyuan Wang , Dongjie Wang , Wangyang Ying , Rui Xie , Haifeng Chen , Yanjie Fu

Multiple hypothesis testing is a significant problem in nearly all neuroimaging studies. In order to correct for this phenomena, we require a reliable estimate of the Family-Wise Error Rate (FWER). The well known Bonferroni correction…

统计计算 · 统计学 2015-02-17 Chris Hinrichs , Vamsi K Ithapu , Qinyuan Sun , Sterling C Johnson , Vikas Singh

An important task in survival analysis is choosing a structure for the relationship between covariates of interest and the time-to-event outcome. For example, the accelerated failure time (AFT) model structures each covariate effect as a…

统计方法学 · 统计学 2025-12-08 Harrison T. Reeder , Kyu Ha Lee , Sebastien Haneuse

Correlated observations are ubiquitous phenomena in a plethora of scientific avenues. Tackling this dependence among test statistics has been one of the pertinent problems in simultaneous inference. However, very little literature exists…

统计理论 · 数学 2024-11-20 Monitirtha Dey

Determining conditional independence (CI) relationships between random variables is a fundamental yet challenging task in machine learning and statistics, especially in high-dimensional settings. Existing generative model-based CI testing…

机器学习 · 计算机科学 2025-05-30 Yixin Ren , Chenghou Jin , Yewei Xia , Li Ke , Longtao Huang , Hui Xue , Hao Zhang , Jihong Guan , Shuigeng Zhou

In this paper, we investigate safety-critical control problem of discrete-time stochastic systems with incomplete information, where safety constraints must be enforced using state estimates obtained from noisy measurements. We develop an…

系统与控制 · 电气工程与系统科学 2026-04-15 Jianing Zhao , Zhuoting Cai , Xiang Yin

Selecting relevant features associated with a given response variable is an important issue in many scientific fields. Quantifying quality and uncertainty of a selection result via false discovery rate (FDR) control has been of recent…

统计方法学 · 统计学 2020-12-17 Chenguang Dai , Buyu Lin , Xin Xing , Jun S. Liu

We apply the concept of distance covariance for testing independence of two long-range dependent time series. As test statistic we propose a linear combination of empirical distance cross-covariances. We derive the asymptotic distribution…

统计理论 · 数学 2026-01-28 Annika Betken , Herold Dehling

This paper introduces a novel methodology that utilizes latency to unveil time-series dependence patterns. A customized statistical test detects memory dependence in event sequences by analyzing their inter-event time distributions.…

计量经济学 · 经济学 2023-09-22 Fabio Vanni , David Lambert