相关论文: Exploring the Influence of Parametrized Pulsatilit…
Several cardiovascular diseases are caused from localised abnormal blood flow such as in the case of stenosis or aneurysms. Prevailing theories propose that the development is caused by abnormal wall-shear stress in focused areas.…
We propose an integrated electromechanical model of the human heart, with focus on the left ventricle, wherein biophysically detailed models describe the different physical phenomena concurring to the cardiac function. We model the…
Bicuspid aortic valve is the most common congenital heart defect, affecting 1-2% of the global population. Patients with bicuspid valves frequently develop dilation and aneurysms of the ascending aorta. Both hemodynamic and genetic factors…
Computer modeling of the cardiovascular system has potential to revolutionize personalized medical care. This is especially promising for congenital heart defects, such as ventricular septal defect (VSD), a hole between the two ventricles…
SUMMARY This work aims at quantifying the effect of inherent uncertainties from cardiac output on the sensitivity of a human compliant arterial network response based on stochastic simulations of a reduced-order pulse wave propagation…
We analyze left atrium haemodynamics, highlighting differences among healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow…
In the United States, heart disease is the leading cause of death for both men and women, accounting for 610,000 deaths each year [1]. Physicians use Magnetic Resonance Imaging (MRI) scans to take images of the heart in order to…
Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…
We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory…
This paper presents a delay-dependent parameter-varying control design approach to address the automated blood pressure regulation problem in the critical patient resuscitation using closed-loop administration of vasopressors. The mean…
Reduced order modeling (ROM) techniques are numerical methods that approximate the solution of parametric partial differential equation (PDE) by properly combining the high-fidelity solutions of the problem obtained for several…
Quantifying the complexity of cardiac systems is fundamental to understanding the onset of rhythm disorders, from mild arrhythmias to life-threatening fibrillation. In this work, we investigate how chaos shows up and evolves in simplified…
- Modeling Human cardiovascular system is always an important issue. One of the most effective methods is using lumped model to reach to a complete model of human cardiovascular system. Such modeling with advanced considerations is used in…
This experimental in vitro work investigates material transport properties in a model left ventricle in the case of aortic regurgitation, a valvular disease characterized by a leaking aortic valve and consequently double-jet filling within…
We numerically investigate the influence of flow development on secondary flow patterns and subsequent wall shear stress distributions in a curved artery model, and we compute vascular metrics commonly used to assess variations in blood…
Physics-based 0D reduced-order models provide computationally lightweight predictions of cardiovascular flows, resolving bulk hemodynamics in fractions of a second that would take days to solve using traditional 3D finite-element…
Objective: Current resuscitation protocols require pausing chest compressions during cardiopulmonary resuscitation (CPR) to check for a pulse. However, pausing CPR during a pulseless rhythm can worsen patient outcome. Our objective is to…
This brief article accompanies a fluid dynamics video presenting the results of a large-eddy simulation of the flow in a realistic left heart. The left heart geometry, from the pulmonary veins to the aortic root, is extracted from medical…
We are concerned with robust and accurate forecasting of multiphase flow rates in wells and pipelines during oil and gas production. In practice, the possibility to physically measure the rates is often limited; besides, it is desirable to…
Objectives: The main objective of this review article is to evaluate the usability of Computational Fluid Dynamics (CFD) as a supporting clinical tool for respiratory system. Data Source: The English articles referred for this review paper…