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The transition from monolayers to multilayered structures in bacterial colonies is a fundamental step in biofilm development. Observed across different morphotypes and species, this transition is triggered within freely growing bacterial…

软凝聚态物质 · 物理学 2021-03-16 Zhihong You , Daniel J. G. Pearce , Anupam Sengupta , Luca Giomi

The diffusion of particles in complex media has gained significant interest due to its dual relevance: probing the viscoelastic properties of materials via microrheology and assessing the extent of particle displacement over time. In this…

软凝聚态物质 · 物理学 2025-06-24 Fabian A. Garcia Daza , Alvaro Rodriguez-Rivas , Fernando Govantes , Alejandro Cuetos

Mechanical forces are obviously important in the assembly of three-dimensional multicellular structures, but their detailed role is often unclear. We have used growing microcolonies of the bacterium \emph{Escherichia coli} to investigate…

细胞行为 · 定量生物学 2014-02-17 Matthew A. A. Grant , Bartłomiej Wacław , Rosalind J. Allen , Pietro Cicuta

Motile bacteria can migrate along chemical gradients in a process known as chemotaxis. When exposed to uniform environmental stress, Escherichia coli cells coordinate their chemotactic responses to form millimeter-sized condensates…

生物物理 · 物理学 2025-05-02 Nir Livne , Ady Vaknin , Oded Agam

In some conditions, bacteria self-organise into biofilms, supracellular structures made of a self-produced embedding matrix, mainly composed on polysaccharides, DNA, proteins and lipids. It is known that bacteria change their colony/matrix…

The activity of growing living bacteria was investigated using real-time and in situ rheology -- in stationary and oscillatory shear. Two different strains of the human pathogen Staphylococcus aureus -- strain COL and its isogenic cell wall…

生物物理 · 物理学 2015-06-19 P. Patricio , P. L. Almeida , R. Portela , R. G. Sobral , I. R. Grilo , T. Cidade , C. R. Leal

Toxic cyanobacterial blooms are a growing environmental concern that affects freshwater ecosystems, drinking water supplies, and public health. The cyanobacterium Microcystis is among the most important bloom forming species. It often grows…

Natural bacterial habitats are often complex fluids with viscoelastic and anisotropic responses to stress; for example, they can take the form of liquid crystals (LCs), with elongated microscopic constituents that collectively align while…

During colony growth, complex interactions regulate the bacterial orientation, leading to the formation of large-scale ordered structures, including topological defects and microdomains. These structures may benefit bacterial strains,…

生物物理 · 物理学 2024-04-10 Mustafa Başaran , Y. Ilker Yaman , Tevfik Can Yuce , Roman Vetter , Askin Kocabas

Bacterial biofilms are usually assumed to originate from individual cells deposited on a surface. However, many biofilm-forming bacteria tend to aggregate in the planktonic phase so that it is possible that many natural and infectious…

The dynamics of growth of bacterial populations has been extensively studied for planktonic cells in well-agitated liquid culture, in which all cells have equal access to nutrients. In the real world, bacteria are more likely to live in…

种群与进化 · 定量生物学 2017-11-01 Xinxian Shao , Andrew Mugler , Justin Kim , Ha Jun Jeong , Bruce Levin , Ilya Nemenman

Bacteria often develop distinct phenotypes to adapt to environmental stress. In particular, they can produce biofilms, dense communities of bacteria that live in a complex extracellular matrix. Bacterial biofilms provide a safe haven from…

Biofilms are communities of bacteria that exhibit a multitude of multiscale biomechanical behaviors. Recent experimental advances have lead to characterizations of these behaviors in terms of measurements of the viscoelastic moduli of…

细胞行为 · 定量生物学 2017-07-19 Jay A. Stotsky , Vanja Dukic , David M. Bortz

Colonies of rod-shaped bacteria constitute a system of colloidal active matter with nematic properties. As a single initial bacterium multiplies through repeated divisions, the resulting colony quickly loses long-range orientational order,…

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

生物物理 · 物理学 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein

Microbial colonies cultured on agar Petri dishes have become a model system to study biological evolution in populations expanding in space. Processes such as clonal segregation and gene surfing have been shown to be affected by…

种群与进化 · 定量生物学 2018-10-17 Craig Watson , Paul Hush , Joshua Williams , Angela Dawson , Nikola Ojkic , Simon Titmuss , Bartlomiej Waclaw

Many mature bacterial colonies and biofilms are complex three-dimensional (3D) structures. One key step in their developmental program is a transition from a two-dimensional (2D) monolayer into a 3D architecture. Despite the importance of…

软凝聚态物质 · 物理学 2020-03-13 Sho C. Takatori , Kranthi K. Mandadapu

In nature, bacterial collectives typically consist of multiple species, which are interacting both biochemically and physically. Nonetheless, past studies on the physical properties of swarming bacteria were focused on axenic (single…

生物物理 · 物理学 2022-06-15 Ajesh Jose , Gil Ariel , Avraham Be'er

Recent studies have shown that packings of cells, both eukaryotic cellular tissues and growing or swarming bacterial colonies, can often be understood as active nematic fluids. A key property of volume-conserving active nematic model…

软凝聚态物质 · 物理学 2022-05-12 Fabian Jan Schwarzendahl , Daniel A. Beller

A diffusion-reaction model for the growth of bacterial colonies is presented. The often observed cooperative behavior developed by bacteria which increases their motility in adverse growth conditions is here introduced as a nonlinear…

凝聚态物理 · 物理学 2009-10-31 A. M. Lacasta , I. R. Cantalapiedra , C. E. Auguet , A. Penaranda , L. Ramirez-Piscina