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Background: Perfusion computed tomography (CT) images the dynamics of a contrast agent through the body over time, and is one of the highest X-ray dose scans in medical imaging. Recently, a theoretically justified reconstruction algorithm…
X-ray computed tomography (CT) based on photon counting detectors (PCD) extends standard CT by counting detected photons in multiple energy bins. PCD data can be used to increase the contrast-to-noise ratio (CNR), increase spatial…
Quantitative estimation of contrast agent concentration is made possible by spectral CT and material decomposition. There are several approaches to modulate the sensitivity of the imaging system to obtain the different spectral channels…
While Model Based Iterative Reconstruction (MBIR) of CT scans has been shown to have better image quality than Filtered Back Projection (FBP), its use has been limited by its high computational cost. More recently, deep convolutional neural…
Inferior soft-tissue contrast resolution is a major limitation of current CT scanners. The aim of the study is to improve the contrast resolution of CT scanners using dual-energy acquisition. Based on dual-energy material decomposition, the…
Spectral computed tomography based on a photon-counting detector (PCD) attracts more and more attentions since it has the capability to provide more accurate identification and quantitative analysis for biomedical materials. The limited…
Spectral computed tomography (CT) has attracted much attention in radiation dose reduction, metal artifacts removal, tissue quantification and material discrimination. The x-ray energy spectrum is divided into several bins, each…
X-Ray based computed tomography (CT) is a well-established technique for determining the three-dimensional structure of an object from its two-dimensional projections. In the past few decades, there have been significant advancements in the…
Photon counting detectors (PCDs) offer promising advancements in computed tomography (CT) imaging by enabling the quantification and 3D imaging of contrast agents and tissue types through multi-energy projections. However, the accuracy of…
In this paper, we present a deep learning algorithm to rapidly obtain high quality CT reconstructions for AM parts. In particular, we propose to use CAD models of the parts that are to be manufactured, introduce typical defects and simulate…
The potential huge advantage of spectral computed tomography (CT) is its capability to provide accuracy material identification and quantitative tissue information. This can benefit clinical applications, such as brain angiography, early…
Computed Tomography (CT) reconstruction of objects with cylindrical symmetry can be performed with a single projection. When the measured rays are parallel, and the axis of symmetry is perpendicular to the optical axis, the data can be…
The recent application of Fourier Based Iterative Reconstruction Method (FIRM) has made it possible to achieve high-quality 2D images from a fan beam Computed Tomography (CT) scan with a limited number of projections in a fast manner. The…
Spectral computed tomography (CT) has a great potential in material identification and decomposition. To achieve high-quality material composition images and further suppress the x-ray beam hardening artifacts, we first propose a one-step…
Model-Based Iterative Reconstruction (MBIR) is important because direct methods, such as Filtered Back-Projection (FBP) can introduce significant noise and artifacts in sparse-angle tomography, especially for time-evolving samples. Although…
Spectral photon-counting X-ray CT (sCT) opens up new possibilities for the quantitative measurement of materials in an object, compared to conventional energy-integrating CT or dual energy CT. However, achieving reliable and accurate…
In this study we evaluated the task-based image quality of a low contrast clinical task for the abdomen protocol (e.g., pancreatic tumour) of three different CT vendors, exploiting three model-based iterative reconstruction (MBIR) levels.…
For single source helical Computed Tomography (CT), both Filtered-Back Projection (FBP) and statistical iterative reconstruction have been investigated. However for dual source CT with flying focal spot (DS-FFS CT), statistical iterative…
Spectral CT offers enhanced material discrimination over single-energy systems and enables quantitative estimation of basis material density images. Water/iodine decomposition in contrast-enhanced CT is one of the most widespread…
Many clinical applications depend critically on the accurate differentiation and classification of different types of materials in patient anatomy. This work introduces a unified framework for accurate nonlinear material decomposition and…