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Background and Purpose: Biopsy is the main determinants of glioma clinical management, but require invasive sampling that fail to detect relevant features because of tumor heterogeneity. The purpose of this study was to evaluate the…

定量方法 · 定量生物学 2019-08-08 Emily E Diller , Sha Cao , Beth Ey , Robert Lober , Jason G Parker

Clinical decision-making in oncology involves multimodal data such as radiology scans, molecular profiling, histopathology slides, and clinical factors. Despite the importance of these modalities individually, no deep learning framework to…

计算机视觉与模式识别 · 计算机科学 2021-07-02 Nathaniel Braman , Jacob W. H. Gordon , Emery T. Goossens , Caleb Willis , Martin C. Stumpe , Jagadish Venkataraman

Automatic segmentation of brain glioma from multimodal MRI scans plays a key role in clinical trials and practice. Unfortunately, manual segmentation is very challenging, time-consuming, costly, and often inaccurate despite human expertise…

图像与视频处理 · 电气工程与系统科学 2020-12-08 Minh H. Vu , Tufve Nyholm , Tommy Löfstedt

Brain tumors are collections of abnormal cells that can develop into masses or clusters. Because they have the potential to infiltrate other tissues, they pose a risk to the patient. The main imaging technique used, MRI, may be able to…

图像与视频处理 · 电气工程与系统科学 2023-09-22 Razia Sultana Misu

Registration of longitudinal brain MRI scans containing pathologies is challenging due to dramatic changes in tissue appearance. Although there has been progress in developing general-purpose medical image registration techniques, they have…

Recently, diffusion models were applied to a wide range of image analysis tasks. We build on a method for image-to-image translation using denoising diffusion implicit models and include a regression problem and a segmentation problem for…

计算机视觉与模式识别 · 计算机科学 2022-04-07 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe C. Cattin

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

图像与视频处理 · 电气工程与系统科学 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

Glioblastoma (GBM) exhibits two principal growth phenotypes: infiltrative, characterized by diffuse invasion with minimal mass effect, and proliferative, characterized by pronounced tissue compression. Their quantitative delineation and…

Tumor heterogeneity is a challenge to designing effective and targeted therapies. Glioma-type identification depends on specific molecular and histological features, which are defined by the official WHO classification CNS. These guidelines…

应用统计 · 统计学 2023-05-23 Roberta Coletti , Mónica L. Mendonça , Susana Vinga , Marta B. Lopes

We explore Generalizable Tumor Segmentation, aiming to train a single model for zero-shot tumor segmentation across diverse anatomical regions. Existing methods face limitations related to segmentation quality, scalability, and the range of…

计算机视觉与模式识别 · 计算机科学 2025-05-06 Yankai Jiang , Peng Zhang , Donglin Yang , Yuan Tian , Hai Lin , Xiaosong Wang

Multimodal deep learning has improved prognostic accuracy for brain tumours by integrating histopathology and genomic data, yet the contribution of volumetric MRI within unified survival frameworks remains unexplored. This pilot study…

计算机视觉与模式识别 · 计算机科学 2026-04-01 Iain Swift , JingHua Ye

Tumour heterogeneity is increasingly recognized as a major obstacle to therapeutic success across neuro-oncology. Gliomas are characterised by distinct combinations of genetic and epigenetic alterations, resulting in complex interactions…

According to the 2021 World Health Organization (WHO) Classification scheme for gliomas, glioma segmentation is a very important basis for diagnosis and genotype prediction. In general, 3D multimodal brain MRI is an effective diagnostic…

图像与视频处理 · 电气工程与系统科学 2025-06-23 Xiaoyu Shi , Shurong Chai , Yinhao Li , Jingliang Cheng , Jie Bai , Guohua Zhao , Yen-Wei Chen

In recent advancement towards computer based diagnostics system, the classification of brain tumor images is a challenging task. This paper mainly focuses on elevating the classification accuracy of brain tumor images with transfer learning…

图像与视频处理 · 电气工程与系统科学 2022-06-20 Pramit Dutta , Khaleda Akhter Sathi , Md. Saiful Islam

Glioma, the malignant brain tumor, requires immediate treatment to improve the survival of patients. Gliomas heterogeneous nature makes the segmentation difficult, especially for sub-regions like necrosis, enhancing tumor, non-enhancing…

图像与视频处理 · 电气工程与系统科学 2020-12-01 Rupal Agravat , Mehul S Raval

The diagnosis of brain cancer relies heavily on medical imaging techniques, with MRI being the most commonly used. It is necessary to perform automatic segmentation of brain tumors on MRI images. This project intends to build an MRI…

图像与视频处理 · 电气工程与系统科学 2024-06-28 Yuxiang Hu , Haowei Yang , Ting Xu , Shuyao He , Jiajie Yuan , Haozhang Deng

Magnetic Resonance Imaging (MRI) is a crucial diagnostic tool, but high-resolution scans are often slow and expensive due to extensive data acquisition requirements. Traditional MRI reconstruction methods aim to expedite this process by…

图像与视频处理 · 电气工程与系统科学 2025-11-11 Emmanuelle Bourigault , Abdullah Hamdi , Amir Jamaludin

Deep learning (DL) has successfully automated dose distribution prediction in radiotherapy planning, enhancing both efficiency and quality. However, existing methods suffer from the over-smoothing problem for their commonly used L1 or L2…

计算机视觉与模式识别 · 计算机科学 2024-07-10 Zhenghao Feng , Lu Wen , Jianghong Xiao , Yuanyuan Xu , Xi Wu , Jiliu Zhou , Xingchen Peng , Yan Wang

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

图像与视频处理 · 电气工程与系统科学 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

图像与视频处理 · 电气工程与系统科学 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman