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相关论文: DrugChat: Towards Enabling ChatGPT-Like Capabiliti…

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Recent advancements in conversational large language models (LLMs), such as ChatGPT, have demonstrated remarkable promise in various domains, including drug discovery. However, existing works mainly focus on investigating the capabilities…

生物大分子 · 定量生物学 2023-05-30 Shengchao Liu , Jiongxiao Wang , Yijin Yang , Chengpeng Wang , Ling Liu , Hongyu Guo , Chaowei Xiao

Social media platforms such as Instagram and Twitter have emerged as critical channels for drug marketing and illegal sale. Detecting and labeling online illicit drug trafficking activities becomes important in addressing this issue.…

计算与语言 · 计算机科学 2023-07-10 Chuanbo Hu , Bin Liu , Xin Li , Yanfang Ye

Large language models (LLMs) have recently taken the world by storm. They can generate coherent text, hold meaningful conversations, and be taught concepts and basic sets of instructions - such as the steps of an algorithm. In this context,…

人机交互 · 计算机科学 2023-03-17 Sara Di Bartolomeo , Giorgio Severi , Victor Schetinger , Cody Dunne

Traditional drug design faces significant challenges due to inherent chemical and biological complexities, often resulting in high failure rates in clinical trials. Deep learning advancements, particularly generative models, offer potential…

This paper introduces DevGPT, a dataset curated to explore how software developers interact with ChatGPT, a prominent large language model (LLM). The dataset encompasses 29,778 prompts and responses from ChatGPT, including 19,106 code…

软件工程 · 计算机科学 2024-02-15 Tao Xiao , Christoph Treude , Hideaki Hata , Kenichi Matsumoto

The birth of ChatGPT, a cutting-edge language model-based chatbot developed by OpenAI, ushered in a new era in AI. However, due to potential pitfalls, its role in rigorous scientific research is not clear yet. This paper vividly showcases…

人工智能 · 计算机科学 2023-10-23 Rui Wang , Hongsong Feng , Guo-Wei Wei

Motivation: Drug repurposing is a viable solution for reducing the time and cost associated with drug development. However, thus far, the proposed drug repurposing approaches still need to meet expectations. Therefore, it is crucial to…

机器学习 · 计算机科学 2024-05-21 Ali Gharizadeh , Karim Abbasi , Amin Ghareyazi , Mohammad R. K. Mofrad , Hamid R. Rabiee

E-learning environments are increasingly harnessing large language models (LLMs) like GPT-3.5 and GPT-4 for tailored educational support. This study introduces an approach that integrates dynamic knowledge graphs with LLMs to offer nuanced…

人工智能 · 计算机科学 2024-12-06 Patrick Ocheja , Brendan Flanagan , Yiling Dai , Hiroaki Ogata

This study presents a comparative analysis of three Generative Pre-trained Transformer (GPT) solutions in a question and answer (Q&A) setting: Drug-GPT 3, Drug-GPT 4, and ChatGPT, in the context of healthcare applications. The objective is…

计算与语言 · 计算机科学 2023-08-01 Giorgos Lysandrou , Roma English Owen , Kirsty Mursec , Grant Le Brun , Elizabeth A. L. Fairley

Recent advances and achievements of artificial intelligence (AI) as well as deep and graph learning models have established their usefulness in biomedical applications, especially in drug-drug interactions (DDIs). DDIs refer to a change in…

Graph Databases (Graph DB) find extensive application across diverse domains such as finance, social networks, and medicine. Yet, the translation of Natural Language (NL) into the Graph Query Language (GQL), referred to as NL2GQL, poses…

计算与语言 · 计算机科学 2024-09-06 Yuanyuan Liang , Keren Tan , Tingyu Xie , Wenbiao Tao , Siyuan Wang , Yunshi Lan , Weining Qian

Graph analysis is fundamental in real-world applications. Traditional approaches rely on SPARQL-like languages or clicking-and-dragging interfaces to interact with graph data. However, these methods either require users to possess high…

人工智能 · 计算机科学 2024-01-24 Yun Peng , Sen Lin , Qian Chen , Lyu Xu , Xiaojun Ren , Yafei Li , Jianliang Xu

Predicting drug-gene associations is crucial for drug development and disease treatment. While graph neural networks (GNN) have shown effectiveness in this task, they face challenges with data sparsity and efficient contrastive learning…

机器学习 · 计算机科学 2025-02-14 Jiayang Wu , Wensheng Gan , Philip S. Yu

Large language models~(LLM) like ChatGPT have become indispensable to artificial general intelligence~(AGI), demonstrating excellent performance in various natural language processing tasks. In the real world, graph data is ubiquitous and…

人工智能 · 计算机科学 2023-07-12 Jiayan Guo , Lun Du , Hengyu Liu , Mengyu Zhou , Xinyi He , Shi Han

Since multidrug combination is widely applied, the accurate prediction of drug-drug interaction (DDI) is becoming more and more critical. In our method, we use graph to represent drug-drug interaction: nodes represent drug; edges represent…

机器学习 · 计算机科学 2022-09-01 Haifan zhou , Wenjing Zhou , Junfeng Wu

Medication recommendations have become an important task in the healthcare domain, especially in measuring the accuracy and safety of medical dialogue systems (MDS). Different from the recommendation task based on electronic health records…

计算与语言 · 计算机科学 2025-05-20 Jialun Zhong , Yanzeng Li , Sen Hu , Yang Zhang , Teng Xu , Lei Zou

Large language models (LLMs) have recently soared in popularity due to their ease of access and the unprecedented ability to synthesize text responses to diverse user questions. However, LLMs like ChatGPT present significant limitations in…

人机交互 · 计算机科学 2023-08-08 Peiling Jiang , Jude Rayan , Steven P. Dow , Haijun Xia

ChatGPT, as a recently launched large language model (LLM), has shown superior performance in various natural language processing (NLP) tasks. However, two major limitations hinder its potential applications: (1) the inflexibility of…

计算与语言 · 计算机科学 2023-09-20 Yucheng Shi , Hehuan Ma , Wenliang Zhong , Qiaoyu Tan , Gengchen Mai , Xiang Li , Tianming Liu , Junzhou Huang

The widespread availability of large language models (LLMs), such as ChatGPT, has significantly impacted education, raising both opportunities and challenges. Students can frequently interact with LLM-powered, interactive learning tools,…

人工智能 · 计算机科学 2026-03-06 Hunter McNichols , Fareya Ikram , Andrew Lan

With the rapid evolution of Natural Language Processing (NLP), Large Language Models (LLMs) like ChatGPT have emerged as powerful tools capable of transforming various sectors. Their vast knowledge base and dynamic interaction capabilities…

计算机与社会 · 计算机科学 2024-01-02 Kevin Wang , Jason Ramos , Ramon Lawrence
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