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Cancer prognosis and survival outcome predictions are crucial for therapeutic response estimation and for stratifying patients into various treatment groups. Medical domains concerned with cancer prognosis are abundant with multiple…

图像与视频处理 · 电气工程与系统科学 2024-02-29 Ruining Deng , Nazim Shaikh , Gareth Shannon , Yao Nie

Massive sized survival datasets are becoming increasingly prevalent with the development of the healthcare industry. Such datasets pose computational challenges unprecedented in traditional survival analysis use-cases. A popular way for…

统计方法学 · 统计学 2023-05-09 Nir Keret , Malka Gorfine

Many diseases are considered to be closely related to the changes in the gut microbial community, including colorectal cancer (CRC), which is one of the most common cancers in the world. The diagnostic classification and etiological…

定量方法 · 定量生物学 2023-10-19 Shan Tang , Shanjun Mao , Yangyang Chen , Falong Tan , Lihua Duan , Cong Pian , Xiangxiang Zeng

Heart failure (HF) is a critical condition in which the accurate prediction of mortality plays a vital role in guiding patient management decisions. However, clinical datasets used for mortality prediction in HF often suffer from an…

机器学习 · 计算机科学 2024-05-29 Hanif Kia , Mansour Vali , Hadi Sabahi

Background: Effective allocation of limited donor lungs in cystic fibrosis (CF) requires accurate survival predictions, so that high-risk patients may be prioritized for transplantation. In practice, decisions about allocation are made…

Despite the fact that cancer survivability rates vary greatly between stages, traditional survival prediction models have frequently been trained and assessed using examples from all combined phases of the disease. This method may result in…

机器学习 · 计算机科学 2026-01-08 Parisa Poorhasani , Bogdan Iancu

Survival outcome assessment is challenging and inherently associated with multiple clinical factors (e.g., imaging and genomics biomarkers) in cancer. Enabling multimodal analytics promises to reveal novel predictive patterns of patient…

计算机视觉与模式识别 · 计算机科学 2023-07-25 Kexin Ding , Mu Zhou , Dimitris N. Metaxas , Shaoting Zhang

This thesis develops computational methods in similarity-preserving hashing, classification, and cancer genomics. Standard space partitioning-based hashing relies on Binary Search Trees (BSTs), but their exponential growth and sparsity…

机器学习 · 计算机科学 2025-08-26 Prashant Gupta

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

Colorectal cancer (CRC) is among the top three malignant tumor types in terms of morbidity and mortality. Histopathological images are the gold standard for diagnosing colon cancer. Cellular nuclei instance segmentation and classification,…

计算机视觉与模式识别 · 计算机科学 2024-01-29 Liangrui Pan , Lian Wang , Zhichao Feng , Zhujun Xu , Liwen Xu , Shaoliang Peng

We develop a neural network model to classify liver cancer patients into high-risk and low-risk groups using genomic data. Our approach provides a novel technique to classify big data sets using neural network models. We preprocess the data…

机器学习 · 统计学 2016-11-28 Ashkan Zeinalzadeh , Tom Wenska , Gordon Okimoto

Precision oncology aims to prescribe the optimal cancer treatment to the right patients, maximizing therapeutic benefits. However, identifying patient subgroups that may benefit more from experimental cancer treatments based on randomized…

统计方法学 · 统计学 2026-01-06 Xingyu Li , Qing Liu , Tony Jiang , Hong Amy Xia , Peng Wei , Brian P. Hobbs

Prediction of Overall Survival (OS) of brain cancer patients from multi-modal MRI is a challenging field of research. Most of the existing literature on survival prediction is based on Radiomic features, which does not consider either…

定量方法 · 定量生物学 2021-09-08 Subhashis Banerjee , Sushmita Mitra , Lawrence O. Hall

Cerebral stroke, the second most substantial cause of death universally, has been a primary public health concern over the last few years. With the help of machine learning techniques, early detection of various stroke alerts is accessible,…

机器学习 · 计算机科学 2022-11-16 Yuru Jing

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

定量方法 · 定量生物学 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Brain tumor is one of the most high-risk cancers which causes the 5-year survival rate of only about 36%. Accurate diagnosis of brain tumor is critical for the treatment planning. However, complete data are not always available in clinical…

图像与视频处理 · 电气工程与系统科学 2021-05-28 Tongxue Zhou , Stéphane Canu , Pierre Vera , Su Ruan

In this paper, we use partially rank-ordered set (PROS) sampling design with multiple concomitants in a breast cancer study and propose a method to estimate the proportion of patients with malignant (cancerous) breast tumours in a given…

统计方法学 · 统计学 2014-11-11 Armin Hatefi , Mohammad Jafari Jozani

Patients with metastatic breast cancer (mBC) undergo repeated computed tomography (CT) imaging during treatment to monitor disease progression. Accurate longitudinal tracking of individual lesions across scans from multiple radiologists is…

Non-parametric maximum likelihood estimation encompasses a group of classic methods to estimate distribution-associated functions from potentially censored and truncated data, with extensive applications in survival analysis. These methods,…

统计方法学 · 统计学 2021-08-05 Justin D. Tubbs , Lane Guolan Chen , Thuan Quoc Thach , Pak C. Sham

In this study, we present a hybrid CNN-RNN approach to investigate long-term survival of subjects in a lung cancer screening study. Subjects who died of cardiovascular and respiratory causes were identified whereby the CNN model was used to…

机器学习 · 计算机科学 2023-03-21 Yaozhi Lu , Shahab Aslani , An Zhao , Ahmed Shahin , David Barber , Mark Emberton , Daniel C. Alexander , Joseph Jacob