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Active forces occurring within cells can drive crucial biological processes that involve spontaneous organization and shape change, such as cell division. Motivated by recent in vitro experiments of nematic droplets of cytoskeletal…

软凝聚态物质 · 物理学 2021-02-16 Fabian Jan Schwarzendahl , Pierre Ronceray , Kimberly L. Weirich , Kinjal Dasbiswas

Movements of molecular motors on cytoskeletal filaments are described by directed walks on a line. Detachment from this line is allowed to occur with a small probability. Motion in the surrounding fluid is described by symmetric random…

统计力学 · 物理学 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

Active polymers possess numerous unique properties that are quite different from those observed in the system of small active molecule due to the intricate interplay between their activity and topological constraints. This study focuses on…

软凝聚态物质 · 物理学 2024-07-09 Jing Li , Bokai Zhang , Zhi-Yong Wang

We provide a minimal model for an active nematic film in contact with both a solid substrate and a passive isotropic fluid, and explore its dynamics in one and two dimensions using a combination of hybrid Lattice Boltzmann simulations and…

软凝聚态物质 · 物理学 2017-02-16 Matthew L. Blow , Marco Aqil , Benno Liebchen , Davide Marenduzzo

The flow properties of a continuum model for an active nematic is studied and compared with recent experiments on suspensions of microtubule bundles and molecular motors. The velocity correlation length is found to be independent of the…

软凝聚态物质 · 物理学 2015-06-15 Sumesh P. Thampi , Ramin Golestanian , Julia M. Yeomans

The mechanical properties of the cell depend crucially on the tension of its cytoskeleton, a biopolymer network that is put under stress by active motor proteins. While the fibrous nature of the network is known to strongly affect the…

软凝聚态物质 · 物理学 2018-05-15 Pierre Ronceray , Chase P. Broedersz , Martin Lenz

Using a microscopic model of interacting polar biofilaments and motor proteins, we characterize the phase diagram of both homogeneous and inhomogeneous states in terms of experimental parameters. The polarity of motor clusters is key in…

软凝聚态物质 · 物理学 2009-11-11 A. Ahmadi , T. B. Liverpool , M. C. Marchetti

Active matter consists of self-propelled elements exhibits fascinating collective motions ranging from biological to artificial systems. Among wide varieties of active matter systems, reconstituted bio-filaments moving on molecular motor…

Using a simple model, we study the fluctuating dynamics of inextensible, semiflexible polar filaments interacting with active and directed force generating centres such as molecular motors. Taking into account the fact that the activity…

软凝聚态物质 · 物理学 2009-11-07 Tanniemola B. Liverpool

Intermediate filaments are cytoskeletal proteins that are key regulators of cell mechanics, a role which is intrinsically tied to their hierarchical structure and their unique ability to accommodate large axial strains. However, how the…

生物物理 · 物理学 2019-03-26 Anders Aufderhorst-Roberts , Gijsje H. Koenderink

We study the elastic properties of a rigid filament in a bath of self-propelled particles. We find that while fully flexible filaments swell monotonically upon increasing the strength of the propelling force, rigid filaments soften for…

软凝聚态物质 · 物理学 2015-06-23 Joseph Harder , Chantal Valeriani , Angelo Cacciuto

Buckling plays a critical role in the transport and dynamics of elastic microfilaments in Stokesian fluids. However, previous work has only considered filaments with homogeneous structural properties. Filament backbone stiffness can be…

软凝聚态物质 · 物理学 2023-01-20 Thomas Nguyen , Harishankar Manikantan

Though jamming transitions are long studied in condensed matter physics and granular systems, much less is known about active jamming (or unjamming), which commonly takes place in living materials. In this paper, we explore, by molecular…

软凝聚态物质 · 物理学 2022-11-09 Varun Venkatesh , Chandana Mondal , Amin Doostmohammadi

"Active nematics" are orientationally ordered but apolar fluids composed of interacting constituents individually powered by an internal source of energy. When activity exceeds a system-size dependent threshold, spatially uniform active…

软凝聚态物质 · 物理学 2017-11-08 Richard Green , John Toner , Vincenzo Vitelli

Networks of biofilaments are essential for the formation of cellular structures that support various biological functions. For the most part, previous studies have investigated the collective dynamics of rod-like biofilaments; however, the…

生物物理 · 物理学 2016-05-18 Hironobu Nogucci , Shuji Ishihara

Using agent-based simulations of self-propelled particles subject to short-range repulsion and nematic alignment we explore the dynamical phases of a dense active material confined to the surface of a sphere. We map the dynamical phase…

软凝聚态物质 · 物理学 2018-04-25 Silke Henkes , M. Cristina Marchetti , Rastko Sknepnek

With exquisite precision and reproducibility, cells orchestrate the cooperative action of thousands of nanometer-sized molecular motors to carry out mechanical tasks at much larger length scales, such as cell motility, division and…

软凝聚态物质 · 物理学 2013-01-08 Tim Sanchez , Daniel T. N. Chen , Stephen J. DeCamp , Michael Heymann , Zvonimir Dogic

Inspired by the complex influence of the globular crosslinking proteins on the formation of biofilament bundles in living organisms, we study and analyze a theoretical model for the structure and thermodynamics of bundles of helical…

软凝聚态物质 · 物理学 2012-01-19 Claus Heussinger , Gregory M. Grason

Understanding active matter has led to new perspectives on biophysics and non-equilibrium dynamics. However, the development of numerical tools for simulating active fluids capable of incorporating non-trivial boundaries or inclusions has…

软凝聚态物质 · 物理学 2024-02-01 Timofey Kozhukhov , Benjamin Loewe , Tyler N. Shendruk

Active nematics are materials composed of mobile, elongated particles that can transform energy from the environment into a mechanical motion. Current experimental realizations of the active nematics are of biological origin and include…

软凝聚态物质 · 物理学 2024-06-05 Andrey Sokolov , Jaideep Katuri , Juan J. de Pablo , Alexey Snezhko