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Predicting gene functions is a challenge for biologists in the post genomic era. Interactions among genes and their products compose networks that can be used to infer gene functions. Most previous studies adopt a linkage assumption, i.e.,…

分子网络 · 定量生物学 2022-04-25 Xin Li , Hsinchun Chen , Jiexun Li , Zhu Zhang

In many real-world scenarios, such as gene knockout experiments, targeted interventions are often accompanied by unknown interventions at off-target sites. Moreover, different units can get randomly exposed to different unknown…

机器学习 · 统计学 2022-10-10 Abhinav Kumar , Gaurav Sinha

The vast amount of biological knowledge accumulated over the years has allowed researchers to identify various biochemical interactions and define different families of pathways. There is an increased interest in identifying pathways and…

应用统计 · 统计学 2011-11-24 Francesco C. Stingo , Yian A. Chen , Mahlet G. Tadesse , Marina Vannucci

Bayesian causal discovery benefits from prior information elicited from domain experts, and in heterogeneous domains any prior knowledge would be badly needed. However, so far prior elicitation approaches have assumed a single causal graph…

机器学习 · 计算机科学 2026-04-30 Zachris Björkman , Jorge Loría , Sophie Wharrie , Samuel Kaski

Causal inference is a science with multi-disciplinary evolution and applications. On the one hand, it measures effects of treatments in observational data based on experimental designs and rigorous statistical inference to draw causal…

统计方法学 · 统计学 2022-09-05 Jingying Zeng , Run Wang

In social sciences and economics, causal inference traditionally focuses on assessing the impact of predefined treatments (or interventions) on predefined outcomes, such as the effect of education programs on earnings. Causal discovery, in…

计量经济学 · 经济学 2024-07-12 Martin Huber

Networks (graphs) in psychology are often restricted to settings without interventions. Here we consider a framework borrowed from biology that involves multiple interventions from different contexts (observations and experiments) in a…

统计方法学 · 统计学 2024-09-23 Lourens Waldorp , Jolanda Kossakowski , Han L. J. van der Maas

In this competition, participants will address two fundamental causal challenges in machine learning in the context of education using time-series data. The first is to identify the causal relationships between different constructs, where a…

计算机与社会 · 计算机科学 2022-09-02 Wenbo Gong , Digory Smith , Zichao Wang , Craig Barton , Simon Woodhead , Nick Pawlowski , Joel Jennings , Cheng Zhang

Software engineering increasingly involves making high-stakes decisions under uncertainty, using signals from code, field data, and socio-technical processes. Recent AI-driven support (e.g., anomaly detection, predictive analytics, AIOps,…

软件工程 · 计算机科学 2026-05-05 Roberto Pietrantuono , Luca Giamattei , Stefano Russo , Julien Siebert , Neil Walkinshaw

The breakthrough in Deep Learning neural networks has transformed the use of AI and machine learning technologies for the analysis of very large experimental datasets. These datasets are typically generated by large-scale experimental…

机器学习 · 计算机科学 2021-10-26 Jeyan Thiyagalingam , Mallikarjun Shankar , Geoffrey Fox , Tony Hey

The discovery of causal relationships from high-dimensional data is a major open problem in bioinformatics. Machine learning and feature attribution models have shown great promise in this context but lack causal interpretation. Here, we…

机器学习 · 计算机科学 2023-04-26 Payam Dibaeinia , Saurabh Sinha

High-throughput preclinical perturbation screens, where the effects of genetic, chemical, or environmental perturbations are systematically tested on disease models, hold significant promise for machine learning-enhanced drug discovery due…

Causal deep learning (CDL) is a new and important research area in the larger field of machine learning. With CDL, researchers aim to structure and encode causal knowledge in the extremely flexible representation space of deep learning…

机器学习 · 计算机科学 2022-12-05 Jeroen Berrevoets , Krzysztof Kacprzyk , Zhaozhi Qian , Mihaela van der Schaar

The discovery of discriminatory bias in human or automated decision making is a task of increasing importance and difficulty, exacerbated by the pervasive use of machine learning and data mining. Currently, discrimination discovery largely…

计算机与社会 · 计算机科学 2019-11-05 Bilal Qureshi , Faisal Kamiran , Asim Karim , Salvatore Ruggieri , Dino Pedreschi

Due to the challenge posed by multi-source and heterogeneous data collected from diverse environments, causal relationships among features can exhibit variations influenced by different time spans, regions, or strategies. This diversity…

机器学习 · 计算机科学 2025-02-11 Lu Liu , Yang Tang , Kexuan Zhang , Qiyu Sun

Causality is receiving increasing attention by the artificial intelligence and machine learning communities. This paper gives an example of modelling a recommender system problem using causal graphs. Specifically, we approached the causal…

信息检索 · 计算机科学 2024-09-17 Emanuele Cavenaghi , Fabio Stella , Markus Zanker

Causal interactions among a group of variables are often modeled by a single causal graph. In some domains, however, these interactions are best described by multiple co-existing causal graphs, e.g., in dynamical systems or genomics. This…

机器学习 · 计算机科学 2024-12-04 Burak Varıcı , Dmitriy Katz-Rogozhnikov , Dennis Wei , Prasanna Sattigeri , Ali Tajer

Recent years have seen rapid progress at the intersection between causality and machine learning. Motivated by scientific applications involving high-dimensional data, in particular in biomedicine, we propose a deep neural architecture for…

机器学习 · 计算机科学 2022-12-12 Kai Lagemann , Christian Lagemann , Bernd Taschler , Sach Mukherjee

The value of research containing novel combinations of molecules can be seen in many innovative and award-winning research programs. Despite calls to use innovative approaches to address common diseases, an increasing majority of research…

社会与信息网络 · 计算机科学 2018-07-02 Konstantin Kuzmin , Xiaoyan Lu , Partha Sarathi Mukherjee , Juntao Zhuang , Chris Gaiteri , Boleslaw K Szymanski

Causal inference has numerous real-world applications in many domains, such as health care, marketing, political science, and online advertising. Treatment effect estimation, a fundamental problem in causal inference, has been extensively…

机器学习 · 计算机科学 2023-02-03 Zhixuan Chu , Jianmin Huang , Ruopeng Li , Wei Chu , Sheng Li