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Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…

流体动力学 · 物理学 2016-07-27 Stefania Scarsoglio , Andrea Saglietto , Fiorenzo Gaita , Luca Ridolfi , Matteo Anselmino

Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

流体动力学 · 物理学 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi

The development and progression of abdominal aortic aneurysms (AAA) are related to complex flow patterns and wall-shear-driven mechanobiological stimuli, yet the quantitative relationship between aneurysmal geometry and hemodynamics remains…

Background and Objective: The role of red blood cell dynamics is emphasised in certain cardiovascular diseases, and thus needs to be closely studied. A multiphase model of blood flow allows the resolution of locally varying density of red…

流体动力学 · 物理学 2021-10-07 Konstantinos G. Lyras , Jack Lee

This study investigates the hemodynamic behavior of blood flow in the aortic arch across anemic, diabetic, and healthy conditions using computational fluid dynamics (CFD) simulations with a non-Newtonian Carreau viscosity model. Velocity…

流体动力学 · 物理学 2025-06-23 Farzana Akter Tina , Hashnayne Ahmed , Hena Rani Biswas

The transitional flow which initiates within the junction (anastomosis) of an arteriovenous fistula (AVF) is known to be a contributing factor in the onset of vascular disease. A novel treatment method involving the implantation of a…

流体动力学 · 物理学 2022-12-13 Sanjiv Gunasekera , Tracie Barber , Olivia Ng , Shannon Thomas , Ramon Varcoe , Charitha de Silva

Vascular access, such as arteriovenous grafts, is crucial for patients undergoing haemodialysis as part of kidney replacement therapy. One of the primary causes of arteriovenous graft failure and loss of patency is disordered blood flow, as…

组织与器官 · 定量生物学 2025-08-11 Guanqi Wang , Thomas Abadie , Ivan Wall , Patricia Pérez Esteban

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

计算机视觉与模式识别 · 计算机科学 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

The influence of blood rheology on hemodynamic parameters is investigated using Computational Fluid Dynamics on blood flow through the human carotid artery. We performed three-dimensional modeling and simulation to study blood flow through…

流体动力学 · 物理学 2024-02-21 Hashnayne Ahmed , Chinmayee Podder

Background: Despite the recent advances in computational fluid dynamics (CFD) techniques applied to blood flow within the left atrium (LA), the relationship between atrial geometry, flow patterns, and blood stasis within the left atrial…

The flow convergence method includes calculation of the proximal isovelocity surface area (PISA) and is widely used to classify mitral regurgitation (MR) with echocardiography. It constitutes a primary decision factor for determination of…

Spatial patterns of elevated wall shear stress and pressure due to blood flow past aortic stenosis (AS) are studied using GPU-accelerated patient-specific computational fluid dynamics. Three cases of moderate AS, one with a dilated…

流体动力学 · 物理学 2022-12-13 Hadi Zolfaghari , Mervyn Andiapen , Andreas Baumbach , Anthony Mathur , Rich R. Kerswell

We numerically investigate the effect of entrance condition on the spatial and temporal evolution of multiple three-dimensional vortex pairs and wall shear stress distribution in a curved artery model. We perform this study using a…

流体动力学 · 物理学 2021-11-10 Christopher Cox , Michael W. Plesniak

Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…

In this work we study the hemodynamics in a stented artery connected either to a collateral artery or to an aneurysmal sac. The blood flow is driven by the pressure drop. Our aim is to characterize the flow-rate and the pressure in the…

偏微分方程分析 · 数学 2010-07-07 Vuk Milisic

In this paper, we present a mathematical and numerical model for blood solidification and its rupture in stenosed arteries. The interaction between the blood flow and an existing stenosis in the arterial wall is modeled as a three…

数值分析 · 数学 2020-05-15 Fatima Abbas , Ayman Mourad

The aortic valve is a three-leaflet passive structure that, driven by pressure differences between the left ventricle and the aorta, opens and closes during the heartbeat to ensure the correct stream direction and flow rate. In elderly…

流体动力学 · 物理学 2021-03-30 Francesco Viola , Valentina Meschini , Roberto Verzicco

We study the impact of using fluid-structure interactions (FSI) to simulate blood flow in a large stenosed artery. We compare typical flow configurations using Navier-Stokes in a rigid geometry setting to a fully coupled FSI model. The…

计算物理 · 物理学 2021-02-01 Lukas Failer , Piotr Minakowski , Thomas Richter

Abdominal aortic aneurysms (AAAs) are pathologic dilatations of the abdominal aorta posing a high fatality risk upon rupture. Studying AAA progression and rupture risk often involves in-silico blood flow modelling with computational fluid…

计算机视觉与模式识别 · 计算机科学 2025-07-31 Patryk Rygiel , Julian Suk , Christoph Brune , Kak Khee Yeung , Jelmer M. Wolterink

There is currently limited understanding of the role played by haemodynamic forces on the processes governing vascular development. One of many obstacles to be overcome is being able to measure those forces, at the required resolution…

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