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相关论文: Multi-Focus Querying of the Human Genome Informati…

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Biologists are leading current research on genome characterization (sequencing, alignment, transcription), providing a huge quantity of raw data about many genome organisms. Extracting knowledge from this raw data is an important process…

定量方法 · 定量生物学 2007-05-23 Nicolas Férey , Pierre-Emmanuel Gros , Joan Hérisson , Rachid Gherbi

Large scale visual understanding is challenging, as it requires a model to handle the widely-spread and imbalanced distribution of <subject, relation, object> triples. In real-world scenarios with large numbers of objects and relations,…

计算机视觉与模式识别 · 计算机科学 2019-08-20 Ji Zhang , Yannis Kalantidis , Marcus Rohrbach , Manohar Paluri , Ahmed Elgammal , Mohamed Elhoseiny

We investigate a densely packed, non-random arrangement of forty-six chromosomes (46,XY) in human nuclei. Here, we model systems-level chromosomal crosstalk by unifying intrinsic parameters (chromosomal length and number of genes) across…

基因组学 · 定量生物学 2017-11-09 Sarosh N. Fatakia , Ishita S. Mehta , Basuthkar J. Rao

The ability to precisely visualize the atomic geometry of the interactions between a drug and its protein target in structural models is critical in predicting the correct modifications in previously identified inhibitors to create more…

生物大分子 · 定量生物学 2018-08-14 Erick Martins Ratamero , Dom Bellini , Christopher G. Dowson , Rudolf A. Roemer

Virtual reality (VR) enables data visualization in an immersive and engaging manner, and it can be used for creating ways to explore scientific data. Here, we use VR for visualization of 3D histology data, creating a novel interface for…

图形学 · 计算机科学 2022-01-31 Kaisa Liimatainen , Leena Latonen , Masi Valkonen , Kimmo Kartasalo , Pekka Ruusuvuori

It has been shown that genome spatial structures largely affect both genome activity and DNA function. Knowing this, many researchers are currently attempting to accurately model genome structures. Despite these increased efforts there…

基因组学 · 定量生物学 2015-07-24 Jackson Nowotny , Avery Wells , Lingfei Xu , Renzhi Cao , Tuan Trieu , Chenfeng He , Jianlin Cheng

Each human genome is a 3 billion base pair set of encoding instructions. Decoding the genome using deep learning fundamentally differs from most tasks, as we do not know the full structure of the data and therefore cannot design…

机器学习 · 计算机科学 2016-05-24 Laura Deming , Sasha Targ , Nate Sauder , Diogo Almeida , Chun Jimmie Ye

The effective visualization of genomic data is crucial for exploring and interpreting complex relationships within and across genes and genomes. Despite advances in developing dedicated bioinformatics software, common visualization tools…

基因组学 · 定量生物学 2024-11-22 Thomas Hackl , Markus Ankenbrand , Bart van Adrichem , David Wilkins , Kristina Haslinger

Realistic human-centric rendering plays a key role in both computer vision and computer graphics. Rapid progress has been made in the algorithm aspect over the years, yet existing human-centric rendering datasets and benchmarks are rather…

Despite progress in perceptual tasks such as image classification, computers still perform poorly on cognitive tasks such as image description and question answering. Cognition is core to tasks that involve not just recognizing, but…

Data visualization is a fundamental tool in genomics research, enabling the exploration, interpretation, and communication of complex genomic features. While machine learning models show promise for transforming data into insightful…

An approach for approximately calculating the number of genes in a genome is presented, which takes into account the average protein length expected for the species. A number of virus, bacterial and eukaryotic genomes are scrutinized.…

基因组学 · 定量生物学 2015-02-13 N. S. Santos-Magalhaes , H. M. de Oliveira

The CellxGene project has enabled access to single-cell data in the scientific community, providing tools for browsed-based no-code analysis of more than 500 annotated datasets. However, single-cell data requires dimensional reduction to…

人机交互 · 计算机科学 2022-12-02 Luke Hyman , Ivo F. Sbalzarini , Stephen Quake , Ulrik Günther

In recent years, substantial advancements have been achieved in understanding the diversity of the human virome and its intricate roles in human health and diseases. Despite this progress, the field of human virome research remains nascent,…

定量方法 · 定量生物学 2024-02-26 Yifan Wu , Yousong Peng

Genomic data visualization is essential for interpretation and hypothesis generation as well as a valuable aid in communicating discoveries. Visual tools bridge the gap between algorithmic approaches and the cognitive skills of…

基因组学 · 定量生物学 2019-11-04 Sabrina Nusrat , Theresa Harbig , Nils Gehlenborg

Scientists have been trying to identify all of the genes in the human genome since the initial draft of the genome was published in 2001. Over the intervening years, much progress has been made in identifying protein-coding genes, and the…

Nucleosome positioning is an important process required for proper genome packing and its accessibility to execute the genetic program in a cell-specific, timely manner. In the recent years hundreds of papers have been devoted to the…

基因组学 · 定量生物学 2017-10-10 Vladimir B. Teif

We investigate the possibility of encoding multiple solutions of a problem in a single chromosome. The best solution encoded in an individual will represent (will provide the fitness of) that individual. In order to obtain some benefits the…

神经与进化计算 · 计算机科学 2021-10-22 Mihai Oltean

How to represent the genetic code? Despite the fact that it is extensively known, the DNA mapping into proteins remains as one of the relevant discoveries of genetics. However, modern genomic signal processing usually requires converting…

其他定量生物学 · 定量生物学 2015-03-10 H. M. de Oliveira , N. S. Santos-Magalhaes

Contouring is an indispensable step in Radiotherapy (RT) treatment planning. However, today's contouring software is constrained to only work with a 2D display, which is less intuitive and requires high task loads. Virtual Reality (VR) has…

人机交互 · 计算机科学 2022-11-09 Chen Chen , Matin Yarmand , Varun Singh , Michael V. Sherer , James D. Murphy , Yang Zhang , Nadir Weibel
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