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In this study, we conduct a study on magnetic hyperthermia treatment when a vessel is located near the tumor. The holistic framework is established to solve the process of tumor treatment. The interstitial tissue fluid, MNP distribution,…

This study was undertaken to develop a system for heat transfer simulation for optimization and treatment planning of magnetic hyperthermia treatment (MHT) using magnetic particle imaging (MPI). First, we performed phantom experiments to…

医学物理 · 物理学 2016-05-27 Natsuo Banura , Atsushi Mimura , Kohei Nishimoto , Kenya Murase

High Intensity Focused Ultrasound (HIFU) is a promising therapy for thermal ablation and hyperthermia, characterised by it noninvasiveness, high penetration depth. Effective HIFU thermo-therapy requires the ability to accurately predict…

医学物理 · 物理学 2020-07-14 Gajendra Singh , Anup Paul , Himanshu Shekhar , Abhijit Paul

During laser and ultrasound thermotherapy it is always desirable to have a precise necrosis of deeply seated tumor preserving the adjoining healthy tissue with minimum thermally induced nociceptive pain sensation to the patient. The aim of…

医学物理 · 物理学 2020-07-29 Abhijit Paul , Anup Paul

Heat-based cancer treatment, so-called hyperthermia, can be used to destroy tumour cells directly or to make them more susceptible to chemotherapy or radiation therapy. To apply heat locally, iron oxide nanoparticles are injected into the…

计算工程、金融与科学 · 计算机科学 2025-02-04 Barbara Wirthl , Paolo Decuzzi , Bernhard A. Schrefler , Wolfgang A. Wall

We report a model for hyperthermia therapies based on heat diffusion in a biological tissue containing a topological defect. Biological tissues behave like active liquid crystals with the presence of topological defects which are likely to…

统计力学 · 物理学 2024-10-02 Andy Manapany , Loriane Didier , Leïla Moueddene , Bertrand Berche , Sébastien Fumeron

We analyze the necrosis growth due to thermal coagulation induced by laser light absorption and limited by heat diffusion into the surrounding live tissue. The tissue is assumed to contain a certain tumor in the undamaged tissue whereof the…

适应与自组织系统 · 物理学 2007-05-23 B. Y. Datsko , V. V. Gafiychuk , I. A. Lubashevsky , A. V. Priezzhev

We develop a multiphysics-based model to predict the response of localized tumors to combined-hyperthermia-radiotherapy (CHR) treatment. This procedure combines hyperthermia (tumor heating) with standard radiotherapy to improve efficacy of…

组织与器官 · 定量生物学 2019-07-05 Japan K. Patel , Richard Vasques , Barry D. Ganapol

Magnetic hyperthermia is a new type of cancer treatment designed for overcoming resistance to chemotherapy during the treatment of solid, inaccessible human tumors. The main challenge of this technology is increasing the local tumoral…

Fast and reliable monitoring of volumetric heat distribution during MRI-guided tumor ablation is an urgent clinical need. In this work, we introduce a method for generating 2.5D thermometry maps from uniformly distributed 2D MRI phase…

图像与视频处理 · 电气工程与系统科学 2021-12-01 Julian Alpers , Daniel L. Reimert , Maximilian Rötzer , Thomas Gerlach , Marcel Gutberlet , Frank Wacker , Bennet Hensen , Christian Hansen

Intracorporeal needle-based therapeutic ultrasound (NBTU) is a minimally invasive option for intervening in malignant brain tumors, commonly used in thermal ablation procedures. This technique is suitable for both primary and metastatic…

Magnetic nanoparticle hyperthermia is an attractive emerging cancer treatment, but the acting microscopic energy deposition mechanisms are not well understood and optimization suffers. We describe several approximate forms for the…

介观与纳米尺度物理 · 物理学 2014-03-26 Daniel B. Reeves , John B. Weaver

A new model is considered to describe the evolution of tissue temperature and water concentration during a thermal ablation process. The aim of this study is to expand the results obtained in Blauth et. al. 2020, where the tissue water…

偏微分方程分析 · 数学 2023-12-22 Federico Herrero-Hervás , Angiolo Farina

Intracorporeal needle-based therapeutic ultrasound (NBTU) offers a minimally invasive approach for the thermal ablation of malignant brain tumors, including both primary and metastatic cancers. NBTU utilizes a high-frequency alternating…

医学物理 · 物理学 2024-09-11 Zhanyue Zhao , Yiwei Jiang , Charles Bales , Yang Wang , Gregory Fischer

Radiotherapy can effectively kill malignant cells, but the doses required to cure cancer patients may inflict severe collateral damage to adjacent healthy tissues. Hyperthermia (HT) is a promising option to improve the outcome of radiation…

Since decades, many techniques have been developed for curing cancer. Here, an effort has been made to cure tumor by inserting a cryoprobe into the target region which is connected to a cryogenic mechanism. This technique is presently used…

医学物理 · 物理学 2022-12-23 G Sai Krishna , Anup Paul

A simplified 2-D model which is an example of regional RF hyperthermia is presented. Human body is inside the wire with exciting current and the electromagnetic energy is concentrated within the tumor. The analyzed model is therefore a…

医学物理 · 物理学 2017-10-31 Piotr Gas

Multimodal oncological strategies which combine chemotherapy or radiotherapy with hyperthermia have a potential of improving the efficacy of the non-surgical methods of cancer treatment. Hyperthermia engages the heat-shock response…

亚细胞过程 · 定量生物学 2013-09-05 Mikołaj Rybiński , Zuzanna Szymańska , Sławomir Lasota , Anna Gambin

Hyperthermia therapy (HT) is used to treat diseases through heating of high temperature usually in conjunction with some other medical therapeutics like chemotherapy and radiotherapy. In this study, we propose a promising thermostatic…

医学物理 · 物理学 2021-09-14 Yuchan Wang , Yuening Wang , Yuan Jie , Paul Carson

Lasers are becoming a more and more important tool in cutting and shaping materials. Improving precision and effectivity is an ongoing demand in science and industry. One possibility are double pulses. Here we study laser ablation of…

材料科学 · 物理学 2015-06-19 Johannes Roth , Armin Krauß , Jan Lotze , Hans-Rainer Trebin
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