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Traumatic brain injury (TBI) disrupts thalamocortical connectivity, contributing to cognitive impairment and post-traumatic epilepsy (PTE). This study presents a novel tractography-based framework that leverages diffusion maps to capture…

定量方法 · 定量生物学 2025-10-21 Akul Sharma , Anand A. Joshi , Richard M. Leahy

Diffusion-weighted MRI is increasingly used to study the normal and abnormal development of fetal brain in-utero. Recent studies have shown that dMRI can offer invaluable insights into the neurodevelopmental processes in the fetal stage.…

Diffusion tensor imaging (DTI) is a popular magnetic resonance imaging technique used to characterize microstructural changes in the brain. DTI studies quantify the diffusion of water molecules in a voxel using an estimated 3x3 symmetric…

统计方法学 · 统计学 2021-03-30 Zhou Lan , Brian J. Reich , Dipankar Bandyopadhyay

Brain cell structure and function reflect neurodevelopment, plasticity and ageing, and changes can help flag pathological processes such as neurodegeneration and neuroinflammation. Accurate and quantitative methods to non-invasively…

Diffusion-weighted imaging (DWI) is a type of Magnetic Resonance Imaging (MRI) technique sensitised to the diffusivity of water molecules, offering the capability to inspect tissue microstructures and is the only in-vivo method to…

计算机视觉与模式识别 · 计算机科学 2024-09-17 Sheng Chen , Zihao Tang , Mariano Cabezas , Xinyi Wang , Arkiev D'Souza , Michael Barnett , Fernando Calamante , Weidong Cai , Chenyu Wang

Diffusion magnetic resonance imaging (dMRI) enables non-invasive investigation of tissue microstructure. The Standard Model (SM) of white matter aims to disentangle dMRI signal contributions from intra- and extra-axonal water compartments.…

图像与视频处理 · 电气工程与系统科学 2026-04-15 Tom Hendriks , Gerrit Arends , Edwin Versteeg , Anna Vilanova , Maxime Chamberland , Chantal M. W. Tax

Streamline classification is essential to identify anatomically meaningful white matter tracts from diffusion MRI (dMRI) tractography. However, current streamline classification methods rely primarily on the geometric features of the…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Haotian Yan , Bocheng Guo , Jianzhong He , Nir A. Sochen , Ofer Pasternak , Lauren J O'Donnell , Fan Zhang

Diffusion MRI tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections. White matter parcellation classifies tractography streamlines into clusters or anatomically meaningful tracts.…

图像与视频处理 · 电气工程与系统科学 2023-01-25 Tengfei Xue , Fan Zhang , Chaoyi Zhang , Yuqian Chen , Yang Song , Alexandra J. Golby , Nikos Makris , Yogesh Rathi , Weidong Cai , Lauren J. O'Donnell

Subtle changes in white matter (WM) microstructure have been associated with normal aging and neurodegeneration. To study these associations in more detail, it is highly important that the WM tracts can be accurately and reproducibly…

图像与视频处理 · 电气工程与系统科学 2020-05-27 Bo Li , Marius de Groot , Rebecca M. E. Steketee , Rozanna Meijboom , Marion Smits , Meike W. Vernooij , M. Arfan Ikram , Jiren Liu , Wiro J. Niessen , Esther E. Bron

We present a method to estimate a multivariate Gaussian distribution of diffusion tensor features in a set of brain regions based on a small sample of healthy individuals, and use this distribution to identify imaging abnormalities in…

应用统计 · 统计学 2017-04-24 Matineh Shaker , Deniz Erdogmus , Jennifer Dy , Sylvain Bouix

Diffusion-weighted magnetic resonance imaging (dMRI) allows non-invasive investigation of whole-brain connectivity, which can potentially help to reveal the brain's global network architecture and abnormalities involved in neurological and…

Diffusion magnetic resonance imaging (dMRI) data allow to reconstruct the 3D pathways of axons within the white matter of the brain as a tractography. The analysis of tractographies has drawn attention from the machine learning and pattern…

机器学习 · 统计学 2015-04-03 Emanuele Olivetti , Thien Bao Nguyen , Paolo Avesani

Tractography is typically performed for each subject using the diffusion tensor imaging (DTI) data in its native subject space rather than in some space common to the entire study cohort. Despite performing tractography on a population…

In structural brain networks the connections of interest consist of white-matter fibre bundles between spatially segregated brain regions. The presence, location and orientation of these white matter tracts can be derived using diffusion…

神经元与认知 · 定量生物学 2012-02-09 M. Hinne , T. Heskes , M. A. J. van Gerven

Estimating intra- and extra-axonal microstructure parameters, such as volume fractions and diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The Standard Model (SM) of diffusion in white matter has…

White matter (WM) tract segmentation based on diffusion magnetic resonance imaging (dMRI) plays an important role in the analysis of human health and brain diseases. However, the annotation of WM tracts is time-consuming and needs…

图像与视频处理 · 电气工程与系统科学 2023-03-28 Hao Xu , Tengfei Xue , Dongnan Liu , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

Diffusion MRI (dMRI) provides a distinctive means to probe the microstructural architecture of living tissue, facilitating applications such as brain connectivity analysis, modeling across multiple conditions, and the estimation of…

图像与视频处理 · 电气工程与系统科学 2025-11-20 Jongyeon Yoon , Elyssa M. McMaster , Michael E. Kim , Gaurav Rudravaram , Kurt G. Schilling , Bennett A. Landman , Daniel Moyer

Diffusion Weighted Imaging (DWI) is an advanced imaging technique commonly used in neuroscience and neurological clinical research through a Diffusion Tensor Imaging (DTI) model. Volumetric scalar metrics including fractional anisotropy,…

图像与视频处理 · 电气工程与系统科学 2022-11-01 Zihao Tang , Xinyi Wang , Lihaowen Zhu , Mariano Cabezas , Dongnan Liu , Michael Barnett , Weidong Cai , Chengyu Wang

Diffusion MRI (dMRI) plays a crucial role in studying brain white matter connectivity. Cortical surface reconstruction (CSR), including the inner whiter matter (WM) and outer pial surfaces, is one of the key tasks in dMRI analyses such as…

Diffusion magnetic resonance imaging (dMRI) provides critical insights into the microstructural and connectional organization of the human brain. However, the availability of high-field, open-access datasets that include raw k-space data…