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Alzheimer's disease is a progressive, debilitating neurodegenerative disease that affects 50 million people globally. Despite this substantial health burden, available treatments for the disease are limited and its fundamental causes remain…

机器学习 · 计算机科学 2024-04-02 Matthew West , Colin Magdamo , Lily Cheng , Yingnan He , Sudeshna Das

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

机器学习 · 计算机科学 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

Contextualized word embeddings have demonstrated state-of-the-art performance in various natural language processing tasks including those that concern historical semantic change. However, language models such as BERT was trained primarily…

计算与语言 · 计算机科学 2022-02-10 Wenjun Qiu , Yang Xu

Bipolar disorder is a chronic mental illness frequently underdiagnosed due to subtle early symptoms and social stigma. This paper explores the advanced natural language processing (NLP) models for recognizing signs of bipolar disorder based…

计算与语言 · 计算机科学 2025-07-22 Khalid Hasan , Jamil Saquer

Learning accurate drug representation is essential for tasks such as computational drug repositioning and prediction of drug side-effects. A drug hierarchy is a valuable source that encodes human knowledge of drug relations in a tree-like…

机器学习 · 计算机科学 2020-06-02 Ke Yu , Shyam Visweswaran , Kayhan Batmanghelich

The availability of biomedical text data and advances in natural language processing (NLP) have made new applications in biomedical NLP possible. Language models trained or fine tuned using domain specific corpora can outperform general…

计算与语言 · 计算机科学 2021-07-12 Usman Naseem , Adam G. Dunn , Matloob Khushi , Jinman Kim

Despite the growing availability of Electronic Health Record (EHR) data, researchers often face substantial barriers in effectively using these data for translational research due to their complexity, heterogeneity, and lack of standardized…

BACKGROUND: In this study, we investigated the efficacy of current state-of-the-art neural sentence embedding models for semantic similarity estimation of sentences from biomedical literature. We trained different neural embedding models on…

计算与语言 · 计算机科学 2021-11-01 Kathrin Blagec , Hong Xu , Asan Agibetov , Matthias Samwald

Electronic medical reports (EHR) contain a vast amount of information that can be leveraged for machine learning applications in healthcare. However, existing survival analysis methods often struggle to effectively handle the complexity of…

计算与语言 · 计算机科学 2025-08-01 Paul Minchella , Loïc Verlingue , Stéphane Chrétien , Rémi Vaucher , Guillaume Metzler

Extraction from raw text to a knowledge base of entities and fine-grained types is often cast as prediction into a flat set of entity and type labels, neglecting the rich hierarchies over types and entities contained in curated ontologies.…

计算与语言 · 计算机科学 2018-07-16 Shikhar Murty* , Patrick Verga* , Luke Vilnis , Irena Radovanovic , Andrew McCallum

A large number of embeddings trained on medical data have emerged, but it remains unclear how well they represent medical terminology, in particular whether the close relationship of semantically similar medical terms is encoded in these…

计算与语言 · 计算机科学 2020-03-26 Claudia Schulz , Damir Juric

Electronic health records (EHRs) contain patients' heterogeneous data that are collected from medical providers involved in the patient's care, including medical notes, clinical events, laboratory test results, symptoms, and diagnoses. In…

人工智能 · 计算机科学 2024-11-12 Shuai Niu , Yunya Song , Qing Yin , Yike Guo , Xian Yang

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

计算与语言 · 计算机科学 2023-12-12 Chris Solomou

Concept normalization in free-form texts is a crucial step in every text-mining pipeline. Neural architectures based on Bidirectional Encoder Representations from Transformers (BERT) have achieved state-of-the-art results in the biomedical…

计算与语言 · 计算机科学 2021-01-26 Zulfat Miftahutdinov , Artur Kadurin , Roman Kudrin , Elena Tutubalina

The growing adoption of electronic health record (EHR) systems has provided unprecedented opportunities for predictive modeling to guide clinical decision making. Structured EHRs contain longitudinal observations of patients across hospital…

机器学习 · 计算机科学 2026-03-12 Deyi Li , Zijun Yao , Qi Xu , Muxuan Liang , Lingyao Li , Zijian Xu , Mei Liu

Clinical notes contain information about patients that goes beyond structured data like lab values and medications. However, clinical notes have been underused relative to structured data, because notes are high-dimensional and sparse. This…

计算与语言 · 计算机科学 2020-12-01 Kexin Huang , Jaan Altosaar , Rajesh Ranganath

Language models pre-trained on biomedical corpora, such as BioBERT, have recently shown promising results on downstream biomedical tasks. Many existing pre-trained models, on the other hand, are resource-intensive and computationally heavy…

计算与语言 · 计算机科学 2022-09-08 Omid Rohanian , Mohammadmahdi Nouriborji , Samaneh Kouchaki , David A. Clifton

In this study, we introduce ExBEHRT, an extended version of BEHRT (BERT applied to electronic health records), and apply different algorithms to interpret its results. While BEHRT considers only diagnoses and patient age, we extend the…

机器学习 · 计算机科学 2023-08-14 Maurice Rupp , Oriane Peter , Thirupathi Pattipaka

Representation learning is a key element of state-of-the-art deep learning approaches. It enables to transform raw data into structured vector space embeddings. Such embeddings are able to capture the distributional semantics of their…

计算与语言 · 计算机科学 2019-10-22 Achim Rettinger , Viktoria Bogdanova , Philipp Niemann

Large pre-trained language models such as BERT have been the driving force behind recent improvements across many NLP tasks. However, BERT is only trained to predict missing words - either behind masks or in the next sentence - and has no…

计算与语言 · 计算机科学 2020-10-26 Nicole Peinelt , Marek Rei , Maria Liakata