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Conventional quantum annealing does not sample all ground states fairly. We demonstrate that fair sampling can be achieved by performing simulated annealing on a quantum annealer. We discuss the problems that occur when implementing this…

量子物理 · 物理学 2020-01-29 Masayuki Yamamoto , Masayuki Ohzeki , Kazuyuki Tanaka

Quantum annealing was originally proposed as an approach for solving combinatorial optimisation problems using quantum effects. D-Wave Systems has released a production model of quantum annealing hardware. However, the inherent noise and…

无序系统与神经网络 · 物理学 2021-03-16 Takehito Sato , Masayuki Ohzeki , Kazuyuki Tanaka

Functions of chemical composition are complex and discrete in nature making it impossible to optimize them with gradient methods. Genetic algorithms, which do not use derivative information, are used to maximize the thermal conductivity of…

材料科学 · 物理学 2018-01-30 Alexander Kerr , Kieran Mullen

Quantum annealing is a promising technique which leverages quantum mechanics to solve hard optimization problems. Considerable progress has been made in the development of a physical quantum annealer, motivating the study of methods to…

量子物理 · 物理学 2017-04-21 Maritza Hernandez , Maliheh Aramon

Quantum kernels hold great promise for offering computational advantages over classical learners, with the effectiveness of these kernels closely tied to the design of the quantum feature map. However, the challenge of designing effective…

量子物理 · 物理学 2024-01-23 Cong Lei , Yuxuan Du , Peng Mi , Jun Yu , Tongliang Liu

Mainstream machine-learning techniques such as deep learning and probabilistic programming rely heavily on sampling from generally intractable probability distributions. There is increasing interest in the potential advantages of using…

量子物理 · 物理学 2018-01-29 Marcello Benedetti , John Realpe-Gómez , Rupak Biswas , Alejandro Perdomo-Ortiz

Generative modeling using samples drawn from the probability distribution constitutes a powerful approach for unsupervised machine learning. Quantum mechanical systems can produce probability distributions that exhibit quantum correlations…

量子物理 · 物理学 2022-10-07 Xun Gao , Eric R. Anschuetz , Sheng-Tao Wang , J. Ignacio Cirac , Mikhail D. Lukin

Recent advances in high-throughput genomic technologies coupled with exponential increases in computer processing and memory have allowed us to interrogate the complex aberrant molecular underpinnings of human disease from a genome-wide…

Exploiting the fact that samples drawn from a quantum annealer inherently follow a Boltzmann-like distribution, annealing-based Quantum Boltzmann Machines (QBMs) have gained increasing popularity in the quantum research community. While…

Deep learning models are used in critical applications, in which mistakes can have serious consequences. Therefore, it is crucial to understand how and why models generate predictions. This understanding provides useful information to check…

We explore the potential application of quantum annealing to address the protein structure problem. To this end, we compare several proposed ab initio protein folding models for quantum computers and analyze their scaling and performance…

量子物理 · 物理学 2026-04-27 Timon Scheiber , Matthias Heller , Andreas Giebel

Quantum annealers are specialized quantum computers for solving combinatorial optimization problems using special characteristics of quantum computing (QC), such as superposition, entanglement, and quantum tunneling. Theoretically, quantum…

软件工程 · 计算机科学 2024-07-29 Xinyi Wang , Asmar Muqeet , Tao Yue , Shaukat Ali , Paolo Arcaini

Quantum annealing has emerged as a promising approach for solving NP-hard optimization problems, leveraging quantum phenomena such as quantum tunneling to navigate complex energy landscapes. However, the extent to which quantum tunneling…

量子物理 · 物理学 2026-03-02 Vishwajeet Ohal , Pierre Boulanger

Quantum machine learning has the potential to enable advances in artificial intelligence, such as solving problems intractable on classical computers. Some fundamental ideas behind quantum machine learning are similar to kernel methods in…

量子物理 · 物理学 2023-08-15 Samuel Bosch , Bobak Kiani , Rui Yang , Adrian Lupascu , Seth Lloyd

Quantum annealing is analogous to simulated annealing with a tunneling mechanism substituting for thermal activation. Its performance has been tested in numerical simulation with mixed conclusions. There is a class of optimization problems…

量子物理 · 物理学 2010-07-19 Thomas Jorg , Florent Krzakala , Jorge Kurchan , A. C. Maggs

Machine learning applications are limited by computational power. In this paper, we gain novel insights into the application of quantum annealing (QA) to machine learning (ML) through experiments in natural language processing (NLP),…

量子物理 · 物理学 2016-03-28 Joseph Dulny , Michael Kim

Numerous scientific and engineering applications require numerically solving systems of equations. Classically solving a general set of polynomial equations requires iterative solvers, while linear equations may be solved either by direct…

量子物理 · 物理学 2019-07-17 Chia Cheng Chang , Arjun Gambhir , Travis S. Humble , Shigetoshi Sota

Feature selection is a machine learning technique for identifying relevant variables in classification and regression models. In single-cell RNA sequencing (scRNA-seq) data analysis, feature selection is used to identify relevant genes that…

基因组学 · 定量生物学 2025-12-02 Selim Romero , Shreyan Gupta , Victoria Gatlin , Robert S. Chapkin , James J. Cai

Quantum annealing provides a powerful platform for simulating magnetic materials and realizing statistical physics models, presenting a compelling alternative to classical Monte Carlo methods. We demonstrate that quantum annealers can…

Training of neural networks (NNs) has emerged as a major consumer of both computational and energy resources. Quantum computers were coined as a root to facilitate training, but no experimental evidence has been presented so far. Here we…

量子物理 · 物理学 2025-12-02 Hao Zhang , Alex Kamenev