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Causal mediation analysis is an important statistical method in social and medical studies, as it can provide insights about why an intervention works and inform the development of future interventions. Currently, most causal mediation…

统计方法学 · 统计学 2016-01-26 Cheng Zheng , David C. Atkins , Melissa A. Lewis , Xiao-Hua Zhou

Mediation analysis is a powerful tool for studying causal pathways between exposure, mediator, and outcome variables of interest. While classical mediation analysis using observational data often requires strong and sometimes unrealistic…

统计方法学 · 统计学 2024-05-20 Rita Qiuran Lyu , Chong Wu , Xinwei Ma , Jingshen Wang

We introduce a new approach to a linear-circular regression problem that relates multiple linear predictors to a circular response. We follow a modeling approach of a wrapped normal distribution that describes angular variables and angular…

统计方法学 · 统计学 2019-09-17 Ali Esmaieeli Sikaroudi , Chiwoo Park

Mediation analysis is concerned with the decomposition of the total effect of an exposure on an outcome into the indirect effect through a given mediator, and the remaining direct effect. This is ideally done using longitudinal measurements…

统计理论 · 数学 2019-12-04 Murthy N Mittinty , Stijn Vansteelandt

Causal inference necessarily relies upon untestable assumptions; hence, it is crucial to assess the robustness of obtained results to violations of identification assumptions. However, such sensitivity analysis is only occasionally…

统计方法学 · 统计学 2025-05-19 Tobias Freidling , Qingyuan Zhao

Estimating treatment effects from observational data is challenging due to two main reasons: (a) hidden confounding, and (b) covariate mismatch (control and treatment groups not having identical distributions). Long lines of works exist…

机器学习 · 计算机科学 2025-04-30 Praharsh Nanavati , Ranjitha Prasad , Karthikeyan Shanmugam

Random-effects meta-analyses of observational studies can produce biased estimates if the synthesized studies are subject to unmeasured confounding. We propose sensitivity analyses quantifying the extent to which unmeasured confounding of…

统计方法学 · 统计学 2017-10-10 Maya B. Mathur , Tyler J. VanderWeele

We develop a method to decompose causal effects on a social network into an indirect effect mediated by the network, and a direct effect independent of the social network. To handle the complexity of network structures, we assume that…

统计方法学 · 统计学 2025-03-07 Alex Hayes , Mark M. Fredrickson , Keith Levin

Decomposing a total causal effect into natural direct and indirect effects is central to revealing causal mechanisms. Conventional methods achieve the decomposition by specifying an outcome model as a linear function of the treatment, the…

统计方法学 · 统计学 2025-06-05 Guanglei Hong

Meta-learning has proven to be successful for few-shot learning across the regression, classification, and reinforcement learning paradigms. Recent approaches have adopted Bayesian interpretations to improve gradient-based meta-learners by…

机器学习 · 计算机科学 2020-12-01 Amrith Setlur , Saket Dingliwal , Barnabas Poczos

\textbf{Background:} Mediation analysis is widely used to investigate how treatments and programs exert their effects, but standard ordinary least squares (OLS) inference can be unreliable when regression errors are non-Gaussian. In medical…

统计方法学 · 统计学 2026-04-10 Mijeong Kim

This paper establishes that so-called instrumental variables enable the identification and the estimation of a fully nonparametric regression model with Berkson-type measurement error in the regressors. An estimator is proposed and proven…

统计理论 · 数学 2013-08-15 Susanne M. Schennach

Causal mediation analysis has been extended to estimate path-specific effects with multiple intermediate variables, isolating treatment effects through a mediator of interest while excluding pathways through its ancestors. Such analyses…

统计方法学 · 统计学 2026-05-12 Yang Bai , Sihan Wu , Baoluo Sun , Yifan Cui

Weighting methods are popular tools for estimating causal effects; assessing their robustness under unobserved confounding is important in practice. In the following paper, we introduce a new set of sensitivity models called "variance-based…

统计方法学 · 统计学 2023-03-14 Melody Huang , Samuel D. Pimentel

Summary statistics of genome-wide association studies (GWAS) teach causal relationship between millions of genetic markers and tens and thousands of phenotypes. However, underlying biological mechanisms are yet to be elucidated. We can…

机器学习 · 统计学 2019-01-25 Yongjin Park , Abhishek Sarkar , Khoi Nguyen , Manolis Kellis

One of the fundamental challenges in drawing causal inferences from observational studies is that the assumption of no unmeasured confounding is not testable from observed data. Therefore, assessing sensitivity to this assumption's…

统计方法学 · 统计学 2024-06-25 Md Abdul Basit , Mahbub A. H. M. Latif , Abdus S Wahed

We propose a cautious Bayesian variable selection routine by investigating the sensitivity of a hierarchical model, where the regression coefficients are specified by spike and slab priors. We exploit the use of latent variables to…

统计方法学 · 统计学 2022-06-20 Tathagata Basu , Matthias C. M. Troffaes , Jochen Einbeck

Standard nonlinear regression is commonly used when modeling indifference points due to its ability to closely follow observed data, resulting in a good model fit. However, standard nonlinear regression currently lacks a reasonable…

统计方法学 · 统计学 2024-06-07 Mingang Kim , Mikhail N. Koffarnus , Christopher T Franck

Causally interpretable meta-analysis combines information from a collection of randomized controlled trials to estimate treatment effects in a target population in which experimentation may not be possible but covariate information can be…

统计方法学 · 统计学 2022-05-03 Jon A. Steingrimsson , David H. Barker , Ruofan Bie , Issa J. Dahabreh

In this paper, we consider the usual linear regression model in the case where the error process is assumed strictly stationary. We use a result from Hannan, who proved a Central Limit Theorem for the usual least squares estimator under…

统计理论 · 数学 2019-06-18 Emmanuel Caron , Sophie Dede