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In observational studies, causal inference relies on several key identifying assumptions. One identifiability condition is the positivity assumption, which requires the probability of treatment be bounded away from 0 and 1. That is, for…

统计方法学 · 统计学 2022-02-21 Yaqian Zhu , Nandita Mitra , Jason Roy

Investigators are increasingly using novel methods for extending (generalizing or transporting) causal inferences from a trial to a target population. In many generalizability and transportability analyses, the trial and the observational…

统计方法学 · 统计学 2022-09-20 Yu-Han Chiu , Issa J. Dahabreh

Causal Machine Learning has emerged as a powerful tool for flexibly estimating causal effects from observational data in both industry and academia. However, causal inference from observational data relies on untestable assumptions about…

Causally interpretable meta-analysis combines information from a collection of randomized controlled trials to estimate treatment effects in a target population in which experimentation may not be possible but covariate information can be…

统计方法学 · 统计学 2022-05-03 Jon A. Steingrimsson , David H. Barker , Ruofan Bie , Issa J. Dahabreh

We consider an empirical likelihood framework for inference for a statistical model based on an informative sampling design. Covariate information is incorporated both through the weights and the estimating equations. The estimator is based…

统计方法学 · 统计学 2019-05-03 Sanjay Chaudhuri , Mark S. Handcock

In some causal inference scenarios, the treatment variable is measured inaccurately, for instance in epidemiology or econometrics. Failure to correct for the effect of this measurement error can lead to biased causal effect estimates.…

机器学习 · 计算机科学 2024-09-13 Antti Pöllänen , Pekka Marttinen

The case$^2$ study, also referred to as the case-case study design, is a valuable approach for conducting inference for treatment effects. Unlike traditional case-control studies, the case$^2$ design compares treatment in two types of cases…

统计方法学 · 统计学 2025-03-03 Kan Chen , Ting Ye , Dylan S. Small

Quantile regression is a powerful tool for detecting exposure-outcome associations given covariates across different parts of the outcome's distribution, but has two major limitations when the aim is to infer the effect of an exposure.…

We introduce several methods for assessing sensitivity to unmeasured confounding in marginal structural models; importantly we allow treatments to be discrete or continuous, static or time-varying. We consider three sensitivity models: a…

统计方法学 · 统计学 2022-10-12 Matteo Bonvini , Edward Kennedy , Valerie Ventura , Larry Wasserman

Latent variable models are popularly used to measure latent factors (e.g., abilities and personalities) from large-scale assessment data. Beyond understanding these latent factors, the covariate effect on responses controlling for latent…

统计方法学 · 统计学 2026-01-12 Jing Ouyang , Chengyu Cui , Kean Ming Tan , Gongjun Xu

The accuracy of probability distributions inferred using machine-learning algorithms heavily depends on data availability and quality. In practical applications it is therefore fundamental to investigate the robustness of a statistical…

机器学习 · 统计学 2018-10-01 Christiane Goergen , Manuele Leonelli

While observational data are routinely used to estimate causal effects of biomedical treatments, doing so requires special methods to adjust for observed confounding. These methods invariably rely on untestable statistical and causal…

统计方法学 · 统计学 2026-03-02 Arman Oganisian

Nowadays, the numerical models of real-world structures are more precise, more complex and, of course, more time-consuming. Despite the growth of a computational effort, the exploration of model behaviour remains a complex task. The…

计算工程、金融与科学 · 计算机科学 2014-10-17 Eliska Janouchova , Anna Kucerova

Sensitivity analysis is widely used to assess the robustness of causal conclusions in observational studies, yet its interaction with the structure of measured covariates is often overlooked. When latent confounders cannot be directly…

统计方法学 · 统计学 2026-02-17 Abhinandan Dalal , Iris Horng , Yang Feng , Dylan S. Small

The study of causality or causal inference - how much a given treatment causally affects a given outcome in a population - goes way beyond correlation or association analysis of variables, and is critical in making sound data driven…

数据库 · 计算机科学 2017-08-09 Sudeepa Roy , Babak Salimi

We consider the estimation of average treatment effects in observational studies and propose a new framework of robust causal inference with unobserved confounders. Our approach is based on distributionally robust optimization and proceeds…

统计方法学 · 统计学 2023-02-06 Dimitris Bertsimas , Kosuke Imai , Michael Lingzhi Li

As the use of machine learning in high impact domains becomes widespread, the importance of evaluating safety has increased. An important aspect of this is evaluating how robust a model is to changes in setting or population, which…

机器学习 · 计算机科学 2021-03-16 Adarsh Subbaswamy , Roy Adams , Suchi Saria

A predictive model makes outcome predictions based on some given features, i.e., it estimates the conditional probability of the outcome given a feature vector. In general, a predictive model cannot estimate the causal effect of a feature…

机器学习 · 计算机科学 2023-04-11 Jiuyong Li , Lin Liu , Ziqi Xu , Ha Xuan Tran , Thuc Duy Le , Jixue Liu

Despite the impressive prediction ability, machine learning models show discrimination towards certain demographics and suffer from unfair prediction behaviors. To alleviate the discrimination, extensive studies focus on eliminating the…

机器学习 · 计算机科学 2023-07-11 Chia-Yuan Chang , Yu-Neng Chuang , Kwei-Herng Lai , Xiaotian Han , Xia Hu , Na Zou

Unmeasured confounding may undermine the validity of causal inference with observational studies. Sensitivity analysis provides an attractive way to partially circumvent this issue by assessing the potential influence of unmeasured…

统计理论 · 数学 2015-07-15 Peng Ding , Tyler VanderWeele