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In digital pathology, different staining procedures and scanners cause substantial color variations in whole-slide images (WSIs), especially across different laboratories. These color shifts result in a poor generalization of deep…

图像与视频处理 · 电气工程与系统科学 2021-07-27 Sophia J. Wagner , Nadieh Khalili , Raghav Sharma , Melanie Boxberg , Carsten Marr , Walter de Back , Tingying Peng

Recently, a number of image-mixing-based augmentation techniques have been introduced to improve the generalization of deep neural networks. In these techniques, two or more randomly selected natural images are mixed together to generate an…

计算机视觉与模式识别 · 计算机科学 2024-05-27 Khawar Islam , Muhammad Zaigham Zaheer , Arif Mahmood , Karthik Nandakumar

Medical images are usually collected from multiple domains, leading to domain shifts that impair the performance of medical image segmentation models. Domain Generalization (DG) aims to address this issue by training a robust model with…

图像与视频处理 · 电气工程与系统科学 2025-06-13 Xi Chen , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

Data augmentation is widely used to enhance generalization in visual classification tasks. However, traditional methods struggle when source and target domains differ, as in domain adaptation, due to their inability to address domain gaps.…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Khawar Islam , Muhammad Zaigham Zaheer , Arif Mahmood , Karthik Nandakumar , Naveed Akhtar

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

计算机视觉与模式识别 · 计算机科学 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

Stain variation is a phenomenon observed when distinct pathology laboratories stain tissue slides that exhibit similar but not identical color appearance. Due to this color shift between laboratories, convolutional neural networks (CNNs)…

计算机视觉与模式识别 · 计算机科学 2020-04-16 David Tellez , Geert Litjens , Peter Bandi , Wouter Bulten , John-Melle Bokhorst , Francesco Ciompi , Jeroen van der Laak

Mixup has become a popular augmentation strategy for image classification, yet its naive pixel-wise interpolation often produces unrealistic images that can hinder learning, particularly in high-stakes medical applications. We propose…

计算机视觉与模式识别 · 计算机科学 2025-09-26 Hugo Carlesso , Maria Eliza Patulea , Moncef Garouani , Radu Tudor Ionescu , Josiane Mothe

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

计算机视觉与模式识别 · 计算机科学 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

CutMix is a vital augmentation strategy that determines the performance and generalization ability of vision transformers (ViTs). However, the inconsistency between the mixed images and the corresponding labels harms its efficacy. Existing…

计算机视觉与模式识别 · 计算机科学 2023-03-20 Mengzhao Chen , Mingbao Lin , ZhiHang Lin , Yuxin Zhang , Fei Chao , Rongrong Ji

The application of supervised deep learning methods in digital pathology is limited due to their sensitivity to domain shift. Digital Pathology is an area prone to high variability due to many sources, including the common practice of…

图像与视频处理 · 电气工程与系统科学 2020-12-24 Jelica Vasiljević , Friedrich Feuerhake , Cédric Wemmert , Thomas Lampert

The different stain styles of cytopathological images have a negative effect on the generalization ability of automated image analysis algorithms. This article proposes a new framework that normalizes the stain style for cytopathological…

图像与视频处理 · 电气工程与系统科学 2019-09-12 Xihao Chen , Jingya Yu , Li Chen , Shaoqun Zeng , Xiuli Liu , Shenghua Cheng

Existing person re-identification models often have low generalizability, which is mostly due to limited availability of large-scale labeled data in training. However, labeling large-scale training data is very expensive and time-consuming,…

计算机视觉与模式识别 · 计算机科学 2021-10-25 Wenhao Wang , Shengcai Liao , Fang Zhao , Cuicui Kang , Ling Shao

Regional dropout strategies have been proposed to enhance the performance of convolutional neural network classifiers. They have proved to be effective for guiding the model to attend on less discriminative parts of objects (e.g. leg as…

计算机视觉与模式识别 · 计算机科学 2019-08-11 Sangdoo Yun , Dongyoon Han , Seong Joon Oh , Sanghyuk Chun , Junsuk Choe , Youngjoon Yoo

The absence of well-structured large datasets in medical computer vision results in decreased performance of automated systems and, especially, of deep learning models. Domain generalization techniques aim to approach unknown domains from a…

图像与视频处理 · 电气工程与系统科学 2024-06-04 Nikolaos Spanos , Anastasios Arsenos , Paraskevi-Antonia Theofilou , Paraskevi Tzouveli , Athanasios Voulodimos , Stefanos Kollias

Deep learning models for computer vision often suffer from poor generalization when deployed in real-world settings, especially when trained on synthetic data due to the well-known Sim2Real gap. Despite the growing popularity of style…

计算机视觉与模式识别 · 计算机科学 2026-04-08 Dustin Eisenhardt , Timothy Schaumlöffel , Alperen Kantarci , Gemma Roig

The detection of nuclei is one of the most fundamental components of computational pathology. Current state-of-the-art methods are based on deep learning, with the prerequisite that extensive labeled datasets are available. The increasing…

图像与视频处理 · 电气工程与系统科学 2019-07-11 Nicolas Brieu , Armin Meier , Ansh Kapil , Ralf Schoenmeyer , Christos G. Gavriel , Peter D. Caie , Günter Schmidt

Deep learning advances have revolutionized automated digital pathology analysis. However, differences in staining protocols and imaging conditions can introduce significant color variability. In deep learning, such color inconsistency often…

计算机视觉与模式识别 · 计算机科学 2025-10-09 Tianyue Xu , Yanlin Wu , Abhai K. Tripathi , Matthew M. Ippolito , Benjamin D. Haeffele

Suboptimal generalization of machine learning models on unseen data is a key challenge which hampers the clinical applicability of such models to medical imaging. Although various methods such as domain adaptation and domain generalization…

图像与视频处理 · 电气工程与系统科学 2021-08-04 Rikiya Yamashita , Jin Long , Snikitha Banda , Jeanne Shen , Daniel L. Rubin

Generative Adversarial Networks (GANs) typically suffer from overfitting when limited training data is available. To facilitate GAN training, current methods propose to use data-specific augmentation techniques. Despite the effectiveness,…

计算机视觉与模式识别 · 计算机科学 2022-11-07 Jie Cao , Mandi Luo , Junchi Yu , Ming-Hsuan Yang , Ran He

Despite notable advancements, the integration of deep learning (DL) techniques into impactful clinical applications, particularly in the realm of digital histopathology, has been hindered by challenges associated with achieving robust…

图像与视频处理 · 电气工程与系统科学 2024-07-04 Sebastian Doerrich , Francesco Di Salvo , Christian Ledig
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