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Artificial intelligence, trained via machine learning or computational statistics algorithms, holds much promise for the improvement of small molecule drug discovery. However, structure-activity data are high dimensional with low…

应用统计 · 统计学 2018-07-25 Oliver Watson , Isidro Cortes-Ciriano , Aimee Taylor , James A Watson

Constraint-based structure learning algorithms infer the causal structure of multivariate systems from observational data by determining an equivalent class of causal structures compatible with the conditional independencies in the data.…

机器学习 · 统计学 2019-05-22 Daniel Chicharro , Stefano Panzeri , Ilya Shpitser

Econometric applications with multi-way clustering often feature a small number of effective clusters or heavy-tailed data, making standard cluster-robust and bootstrap inference unreliable in finite samples. In this paper, we develop a…

统计方法学 · 统计学 2026-01-14 Wenxuan Guo , Panos Toulis , Yuhao Wang

This paper presents robust inference methods for general linear hypotheses in linear panel data models with latent group structure in the coefficients. We employ a selective conditional inference approach, deriving the conditional…

计量经济学 · 经济学 2025-11-25 Oguzhan Akgun , Ryo Okui

We propose a hybrid combination of active inference and behavior trees (BTs) for reactive action planning and execution in dynamic environments, showing how robotic tasks can be formulated as a free-energy minimization problem. The proposed…

机器人学 · 计算机科学 2022-11-28 Corrado Pezzato , Carlos Hernandez Corbato , Stefan Bonhof , Martijn Wisse

Binomial tree methods (BTM) and explicit difference schemes (EDS) for the variational inequality model of American options with time dependent coefficients are studied. When volatility is time dependent, it is not reasonable to assume that…

证券定价 · 定量金融 2018-08-23 Hyong-chol O , Song-gon Jang , Il-Gwang Jon , Mun-Chol Kim , Gyong-Ryol Kim , Hak-Yong Kim

Multi-arm bandits are gaining popularity as they enable real-world sequential decision-making across application areas, including clinical trials, recommender systems, and online decision-making. Consequently, there is an increased desire…

统计方法学 · 统计学 2023-03-01 Dae Woong Ham , Iavor Bojinov , Michael Lindon , Martin Tingley

Survival analysis of right censored data arises often in many areas of research including medical research. Effect of covariates (and their interactions) on survival distribution can be studied through existing methods which requires to…

统计方法学 · 统计学 2021-08-11 Madan Gopal Kundu , Samiran Ghosh

A simple way to model phenotypic evolution is to assume that after splitting, the trait values of the sister species diverge as independent Brownian motions. Relying only on a prior distribution for the underlying species tree (conditioned…

种群与进化 · 定量生物学 2013-05-14 Serik Sagitov , Krzysztof Bartoszek

Typically, machine learning models are trained and evaluated without making any distinction between users (e.g, using traditional hold-out and cross-validation). However, this produces inaccurate performance metrics estimates in multi-user…

机器学习 · 计算机科学 2023-12-11 Enrique Garcia-Ceja , Luciano Garcia-Banuelos , Nicolas Jourdan

Aleatoric uncertainty quantification seeks for distributional knowledge of random responses, which is important for reliability analysis and robustness improvement in machine learning applications. Previous research on aleatoric uncertainty…

机器学习 · 计算机科学 2022-06-10 Ziyi Huang , Henry Lam , Haofeng Zhang

Causal graphical models can encode large amounts structural knowledge, both from the background knowledge of domain experts and the structural knowledge discovered from randomized experiments or observational data. However, though we may…

机器学习 · 计算机科学 2026-04-07 Katherine Avery , Chinmay Pendse , David Jensen

Tree-based regression and classification has become a standard tool in modern data science. Bayesian Additive Regression Trees (BART) has in particular gained wide popularity due its flexibility in dealing with interactions and non-linear…

统计计算 · 统计学 2022-09-13 Alan Inglis , Andrew Parnell , Catherine Hurley

Remarkable progress has been made in difference-in-differences (DID) approaches to causal inference that estimate the average effect of a treatment on the treated (ATT). Of these, the semiparametric DID (SDID) approach incorporates a…

统计方法学 · 统计学 2026-03-09 Takamichi Baba , Yoshiyuki Ninomiya

Additive models, such as produced by gradient boosting, and full interaction models, such as classification and regression trees (CART), are widely used algorithms that have been investigated largely in isolation. We show that these models…

The celebrated multi-armed bandit problem in decision theory models the basic trade-off between exploration, or learning about the state of a system, and exploitation, or utilizing the system. In this paper we study the variant of the…

数据结构与算法 · 计算机科学 2013-06-19 Sudipto Guha , Kamesh Munagala

This paper studies inference in two-stage randomized experiments under covariate-adaptive randomization. In the initial stage of this experimental design, clusters (e.g., households, schools, or graph partitions) are stratified and randomly…

计量经济学 · 经济学 2026-01-16 Jizhou Liu

When a subgroup is identified from the data, it must be evaluated in a replicable way. The usual in-sample approach, which evaluates the post-hoc identified subgroup as predefined, might suffer from selection bias. This issue of in-sample…

统计方法学 · 统计学 2026-05-06 Shuoxun Xu , Xinzhou Guo

Causal discovery from observational data is a fundamental task in artificial intelligence, with far-reaching implications for decision-making, predictions, and interventions. Despite significant advances, existing methods can be broadly…

机器学习 · 计算机科学 2026-02-06 Jincheng Zhou , Mengbo Wang , Anqi He , Yumeng Zhou , Hessam Olya , Murat Kocaoglu , Bruno Ribeiro

Tree data structures, such as red-black trees, quad trees, treaps, or tries, are fundamental tools in computer science. A classical problem in concurrency is to obtain expressive, efficient, and scalable versions of practical tree data…

数据库 · 计算机科学 2023-10-10 Ilya Kokorin , Dan Alistarh , Vitaly Aksenov