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Understanding the dynamical behavior of complex systems from their underlying network architectures is a long-standing question in complexity theory. Therefore, many metrics have been devised to extract network features like motifs,…

神经元与认知 · 定量生物学 2024-09-05 Bryant Avila , Pedro Augusto , David Phillips , Tommaso Gili , Manuel Zimmer , Hernán A. Makse

The neural connectome of the nematode Caenorhabditis elegans has been completely mapped, yet in spite of being one of the smallest connectomes (302 neurons), the design principles that explain how the connectome structure determines its…

无序系统与神经网络 · 物理学 2020-01-08 Flaviano Morone , Hernan A. Makse

The connectome, or the entire connectivity of a neural system represented by network, ranges various scales from synaptic connections between individual neurons to fibre tract connections between brain regions. Although the modularity they…

神经元与认知 · 定量生物学 2014-10-01 Jinseop S. Kim , Marcus Kaiser

Despite recent interest in reconstructing neuronal networks, complete wiring diagrams on the level of individual synapses remain scarce and the insights into function they can provide remain unclear. Even for Caenorhabditis elegans, whose…

神经元与认知 · 定量生物学 2011-02-07 Lav R. Varshney , Beth L. Chen , Eric Paniagua , David H. Hall , Dmitri B. Chklovskii

We investigate how locomotory behavior is generated in the brain focusing on the paradigmatic connectome of nematode Caenorhabditis elegans (C. elegans) and on neuronal activity patterns that control forward locomotion. We map the neuronal…

适应与自组织系统 · 物理学 2020-06-17 Thomas Maertens , Eckehard Schöll , Jorge Ruiz , Philipp Hövel

A central problem of neuroscience involves uncovering the principles governing the organization of nervous systems which ensure robustness in brain development. The nematode Caenorhabditis elegans provides us with a model organism for…

神经元与认知 · 定量生物学 2020-07-01 Anand Pathak , Nivedita Chatterjee , Sitabhra Sinha

Control is essential to the functioning of any neural system. Indeed, under healthy conditions the brain must be able to continuously maintain a tight functional control between the system's inputs and outputs. One may therefore hypothesise…

The nematode Caenorhabditis elegans, with information on neural connectivity, three-dimensional position and cell linage provides a unique system for understanding the development of neural networks. Although C. elegans has been widely…

生物物理 · 物理学 2011-01-17 Sreedevi Varier , Marcus Kaiser

The connectome describes the complete set of synaptic contacts through which neurons communicate. While the architecture of the $\textit{C. elegans}$ connectome has been extensively characterized, much less is known about the organization…

神经元与认知 · 定量生物学 2025-09-18 Sophie Dvali , Caio Seguin , Richard Betzel , Andrew M. Leifer

Symmetries found through automorphisms or graph fibrations provide important insights in network analysis. Symmetries identify clusters of robust synchronization in the network which improves the understanding of the functionality of…

定量方法 · 定量生物学 2022-07-27 Ian Leifer , David Phillips , Francesco Sorrentino , Hernán A. Makse

We exploit flow propagation on the directed neuronal network of the nematode Caenorhabditis elegans to reveal dynamically relevant features of its connectome. We find flow-based groupings of neurons at different levels of granularity, which…

神经元与认知 · 定量生物学 2016-08-09 Karol A. Bacik , Michael T. Schaub , Mariano Beguerisse-Díaz , Yazan N. Billeh , Mauricio Barahona

Probing the developing neural circuitry in Caenorhabditis elegans has enhanced our understanding of nervous systems. The C. elegans connectome, like those of other species, is characterized by a rich club of densely connected neurons…

神经元与认知 · 定量生物学 2021-08-26 Alec Helm , Ann S. Blevins , Danielle S. Bassett

{\it Caenorhabditis elegans} nematode worms are the only animals with the known detailed neural connectivity diagram, well characterized genomics, and relatively simple quantifiable behavioral output. With this in mind, many researchers…

神经元与认知 · 定量生物学 2019-10-17 Jan Karbowski

Dynamical systems with a network structure can display collective behaviour such as synchronisation. Golubitsky and Stewart observed that all the robustly synchronous dynamics of a network is contained in the dynamics of its quotient…

动力系统 · 数学 2014-10-23 Eddie Nijholt , Bob Rink , Jan Sanders

The nervous system of the nematode soil worm Caenorhabditis elegans exhibits remarkable complexity despite the worm's small size. A general challenge is to better understand the relationship between neural organization and neural activity…

神经元与认知 · 定量生物学 2020-10-30 Alejandro Morales , Tom Froese

A fibration of graphs is an homomorphism that is a local isomorphism of in-neighbourhoods, much in the same way a covering projection is a local isomorphism of neighbourhoods. Recently, it has been shown that graph fibrations are useful…

定量方法 · 定量生物学 2022-11-23 Paolo Boldi , Ian Leifer , Hernán A. Makse

There is renewed interest in modeling and understanding the nervous system of the nematode $\textit{Caenorhabditis elegans}$ ($\textit{C. elegans}$), as this small model system provides a path to bridge the gap between nervous system…

神经元与认知 · 定量生物学 2025-05-20 Quilee Simeon , Anshul Kashyap , Konrad P Kording , Edward S Boyden

Based on recent advances in fibration symmetry theory, we investigate how structural symmetries influence synchronization in systems with higher-order interactions (HOI). Using bipartite graph representations, we identify a node partition…

动力系统 · 数学 2026-01-12 Margherita Bertè , Tommaso Gili

We investigate joint graph inference for the chemical and electrical connectomes of the \textit{Caenorhabditis elegans} roundworm. The \textit{C.elegans} connectomes consist of $253$ non-isolated neurons with known functional attributes,…

应用统计 · 统计学 2015-08-06 Li Chen , Joshua T. Vogelstein , Vince Lyzinski , Carey E. Priebe

The presence of synchronized clusters in neuron networks is a hallmark of information transmission and processing. The methods commonly used to study cluster synchronization in networks of coupled oscillators ground on simplifying…

动力系统 · 数学 2020-07-09 Matteo Lodi , Fabio Della Rossa , Francesco Sorrentino , Marco Storace
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