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Monitoring physiological responses to hemodynamic stress can help in determining appropriate treatment and ensuring good patient outcomes. Physicians' intuition suggests that the human body has a number of physiological response patterns to…

机器学习 · 计算机科学 2019-11-14 Chufan Gao , Fabian Falck , Mononito Goswami , Anthony Wertz , Michael R. Pinsky , Artur Dubrawski

Vessel stenosis is a major risk factor in cardiovascular diseases (CVD). To analyze the degree of vessel stenosis for supporting the treatment management, extraction of coronary artery area from Computed Tomographic Angiography (CTA) is…

图像与视频处理 · 电气工程与系统科学 2019-07-30 Yo-Chuan Chen , Yi-Chen Lin , Ching-Ping Wang , Chia-Yen Lee , Wen-Jeng Lee , Tzung-Dau Wang , Chung-Ming Chen

Cerebral aneurysms and arteriovenous malformations are life-threatening hemodynamic pathologies of the brain. While surgical intervention is often essential to prevent fatal outcomes, it carries significant risks both during the procedure…

In this study, hypertension is utilized as an indicator of individual vascular damage. This damage can be identified through machine learning techniques, providing an early risk marker for potential major cardiovascular events and offering…

Early identification of high risk heart failure (HF) patients is key to timely allocation of life-saving therapies. Hemodynamic assessments can facilitate risk stratification and enhance understanding of HF trajectories. However, risk…

机器学习 · 计算机科学 2023-06-13 Josephine Lamp , Yuxin Wu , Steven Lamp , Prince Afriyie , Kenneth Bilchick , Lu Feng , Sula Mazimba

The paper discusses a stabilization of a finite element method for the equations of fluid motion in a time-dependent domain. After experimental convergence analysis, the method is applied to simulate a blood flow in the right ventricle of a…

Physics-based simulation for fluid flow in porous media is a computational technology to predict the temporal-spatial evolution of state variables (e.g. pressure) in porous media, and usually requires high computational expense due to its…

流体动力学 · 物理学 2021-05-11 Bicheng Yan , Dylan Robert Harp , Bailian Chen , Rajesh J. Pawar

Automated construction of surface geometries of cardiac structures from volumetric medical images is important for a number of clinical applications. While deep-learning-based approaches have demonstrated promising reconstruction precision,…

图像与视频处理 · 电气工程与系统科学 2021-09-15 Fanwei Kong , Nathan Wilson , Shawn C. Shadden

Analyzing large-scale data from simulations of turbulent flows is memory intensive, requiring significant resources. This major challenge highlights the need for data compression techniques. In this study, we apply a physics-informed Deep…

流体动力学 · 物理学 2022-07-26 Mohammadreza Momenifar , Enmao Diao , Vahid Tarokh , Andrew D. Bragg

The accurate segmentation of Coronary Computed Tomography Angiography (CCTA) images holds substantial clinical value for the early detection and treatment of Coronary Heart Disease (CHD). The Transformer, utilizing a self-attention…

图像与视频处理 · 电气工程与系统科学 2023-10-10 Chenchu Xu , Meng Li , Xue Wu

Computational hemodynamics models are becoming increasingly useful in the management and prognosis of complex, multiscale pathologies, including those attributed to the development of pulmonary vascular disease. However, diseases like…

组织与器官 · 定量生物学 2025-06-06 Mitchel J. Colebank , Naomi C. Chesler

High-fidelity modeling of turbulent flows is one of the major challenges in computational physics, with diverse applications in engineering, earth sciences and astrophysics, among many others. The rising popularity of high-fidelity…

流体动力学 · 物理学 2019-03-06 Arvind Mohan , Don Daniel , Michael Chertkov , Daniel Livescu

Cardiovascular disease (CVD) accounts for about half of non-communicable diseases. Vessel stenosis in the coronary artery is considered to be the major risk of CVD. Computed tomography angiography (CTA) is one of the widely used noninvasive…

图像与视频处理 · 电气工程与系统科学 2023-10-18 An Zeng , Chunbiao Wu , Meiping Huang , Jian Zhuang , Shanshan Bi , Dan Pan , Najeeb Ullah , Kaleem Nawaz Khan , Tianchen Wang , Yiyu Shi , Xiaomeng Li , Guisen Lin , Xiaowei Xu

Coronary Microvascular Dysfunction (CMD) is characterized by impaired vasodilation and can lead to insufficient blood flow to the myocardium during stress or exertion, affecting millions of people globally. Despite their diagnostic value,…

计算工程、金融与科学 · 计算机科学 2025-08-04 Haizhou Yang , Jiyang Zhang , Ismael Z. Assi , Brahmajee K. Nallamothu , Krishna Garikipati , C. Alberto Figueroa

Detection of coronary artery stenosis in coronary CT angiography (CCTA) requires highly personalized surface meshes enclosing the coronary lumen. In this work, we propose to use graph convolutional networks (GCNs) to predict the spatial…

图像与视频处理 · 电气工程与系统科学 2019-08-16 Jelmer M. Wolterink , Tim Leiner , Ivana Išgum

Coronary Artery Disease (CAD) is one of the most common forms of heart disease, which is caused by a buildup of atherosclerotic plaque (known as stenosis) in the coronary arteries, leading to insufficient supplement of blood, oxygen, and…

计算工程、金融与科学 · 计算机科学 2024-09-06 Haizhou Yang , C. Alberto Figueroa , Krishna Garikipati

Computational fluid dynamics (CFD) in many cases requires designing 3D models manually, which is a tedious task that requires specific skills. In this paper, we present a novel method for performing CFD directly on scanned 3D point clouds.…

In several problems involving fluid flows, Computational Fluid Dynamics (CFD) provides detailed quantitative information, and often allows the designer to successfully optimize the system, by minimizing a cost function. Sometimes, however,…

流体动力学 · 物理学 2023-12-19 Andrea Schillaci , Kazuto Hasegawa , Carlotta Pipolo , Giacomo Boracchi , Maurizio Quadrio

While deep learning has shown tremendous success in a wide range of domains, it remains a grand challenge to incorporate physical principles in a systematic manner to the design, training, and inference of such models. In this paper, we aim…

计算物理 · 物理学 2020-06-16 Rui Wang , Karthik Kashinath , Mustafa Mustafa , Adrian Albert , Rose Yu

Providing closed and well-connected boundaries of coronary artery is essential to assist cardiologists in the diagnosis of coronary artery disease (CAD). Recently, several deep learning-based methods have been proposed for boundary…