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相关论文: BOSS -- Biomarker Optimal Segmentation System

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Multimodal brain tumor segmentation challenge (BraTS) brings together researchers to improve automated methods for 3D MRI brain tumor segmentation. Tumor segmentation is one of the fundamental vision tasks necessary for diagnosis and…

图像与视频处理 · 电气工程与系统科学 2020-01-08 Andriy Myronenko , Ali Hatamizadeh

Medical image segmentation is crucial for clinical diagnosis. However, current losses for medical image segmentation mainly focus on overall segmentation results, with fewer losses proposed to guide boundary segmentation. Those that do…

图像与视频处理 · 电气工程与系统科学 2023-08-02 Fan Sun , Zhiming Luo , Shaozi Li

Balancing influential covariates is crucial for valid treatment comparisons in clinical studies. While covariate-adaptive randomization is commonly used to achieve balance, its performance can be inadequate when the number of baseline…

统计方法学 · 统计学 2024-12-30 Ziqing Guo , Yang Liu , Lucy Xia

Accurate and early prediction of a disease allows to plan and improve a patient's quality of future life. During pandemic situations, the medical decision becomes a speed challenge in which physicians have to act fast to diagnose and…

机器学习 · 计算机科学 2022-06-09 Pierluigi Costanzo , Kalia Orphanou

Reliable brain tumor segmentation in MRI is indispensable for treatment planning and outcome monitoring, yet models trained on curated benchmarks often fail under domain shifts arising from scanner and protocol variability as well as…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Yuanhan Wang , Yifei Chen , Shuo Jiang , Wenjing Yu , Mingxuan Liu , Beining Wu , Jinying Zong , Feiwei Qin , Changmiao Wang , Qiyuan Tian

Optimal design is a critical yet challenging task within many applications. This challenge arises from the need for extensive trial and error, often done through simulations or running field experiments. Fortunately, sequential optimal…

机器学习 · 计算机科学 2025-03-25 Xubo Yue , Raed Al Kontar , Albert S. Berahas , Yang Liu , Blake N. Johnson

The pathogenesis of cancer in human is still poorly understood. With the rapid development of high-throughput sequencing technologies, huge volumes of cancer genomics data have been generated. Deciphering those data poses great…

基因组学 · 定量生物学 2016-04-06 Junhua Zhang , Shihua Zhang

Breast cancer is one of the most serious disease affecting women's health. Due to low cost, portable, no radiation, and high efficiency, breast ultrasound (BUS) imaging is the most popular approach for diagnosing early breast cancer.…

计算机视觉与模式识别 · 计算机科学 2019-10-24 Kuan Huang , Yingtao Zhang , H. D. Cheng , Ping Xing , Boyu Zhang

The task of medical image segmentation presents unique challenges, necessitating both localized and holistic semantic understanding to accurately delineate areas of interest, such as critical tissues or aberrant features. This complexity is…

图像与视频处理 · 电气工程与系统科学 2023-08-22 Pranav Singh , Luoyao Chen , Mei Chen , Jinqian Pan , Raviteja Chukkapalli , Shravan Chaudhari , Jacopo Cirrone

The assessment of imaging biomarkers is critical for advancing precision medicine and improving disease characterization. Despite the availability of methods to derive disease heterogeneity metrics in imaging studies, a robust framework for…

Imaging biomarkers in neuro-oncology are used for diagnosis, prognosis and treatment response monitoring. Magnetic resonance imaging is typically used throughout the patient pathway because routine structural imaging provides detailed…

定量方法 · 定量生物学 2019-10-21 Thomas Booth

Bayesian optimization (BO) is an effective technique for black-box optimization. However, its applicability is typically limited to moderate-budget problems due to the cubic complexity of fitting the Gaussian process (GP) surrogate model.…

机器学习 · 统计学 2025-10-13 Qiyu Wei , Haowei Wang , Zirui Cao , Songhao Wang , Richard Allmendinger , Mauricio A Álvarez

Brain tumors remain a critical global health challenge, necessitating advancements in diagnostic techniques and treatment methodologies. A tumor or its recurrence often needs to be identified in imaging studies and differentiated from…

图像与视频处理 · 电气工程与系统科学 2024-03-18 Shashidhar Reddy Javaji , Sovesh Mohapatra , Advait Gosai , Gottfried Schlaug

Obtaining large-scale medical data, annotated or unannotated, is challenging due to stringent privacy regulations and data protection policies. In addition, annotating medical images requires that domain experts manually delineate…

计算机视觉与模式识别 · 计算机科学 2025-05-16 Tushar Kataria , Shireen Y. Elhabian

Precision medicine aims to optimize treatment by identifying patient subgroups most likely to benefit from specific interventions. To support this goal, we introduce fkbma, an R package that implements a Bayesian model averaging approach…

统计方法学 · 统计学 2025-03-18 Lara Maleyeff , Shirin Golchi , Erica E. M. Moodie

This study explores the optimization of the DRAGON Longformer base model for clinical text classification, specifically targeting the binary classification of medical case descriptions. A dataset of 500 clinical cases containing structured…

计算与语言 · 计算机科学 2025-07-15 Mingchuan Yang , Ziyuan Huang

Therapeutic advancements in oncology have shifted towards targeted therapy based on genomic aberrations. This necessitates innovative statistical approaches in clinical trials, particularly in master protocol studies. Basket trials, a type…

应用统计 · 统计学 2025-02-12 Antonios Daletzakis , Rutger van den Bor , Vincent van der Noort , Kit CB Roes

Automated segmentation proves to be a valuable tool in precisely detecting tumors within medical images. The accurate identification and segmentation of tumor types hold paramount importance in diagnosing, monitoring, and treating highly…

图像与视频处理 · 电气工程与系统科学 2024-03-15 Fadillah Maani , Anees Ur Rehman Hashmi , Mariam Aljuboory , Numan Saeed , Ikboljon Sobirov , Mohammad Yaqub

The development of molecular signatures for the prediction of time-to-event outcomes is a methodologically challenging task in bioinformatics and biostatistics. Although there are numerous approaches for the derivation of marker…

应用统计 · 统计学 2014-01-09 Andreas Mayr , Matthias Schmid
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