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Label-free single-cell imaging offers a scalable, non-invasive alternative to fluorescence-based cytometry, yet inferring molecular phenotypes directly from bright-field morphology remains challenging. We present a unified Deep Learning…

计算机视觉与模式识别 · 计算机科学 2026-05-15 Saqib Nazir , Ardhendu Behera

The biomechanical properties of cells and tissues play an important role in our fundamental understanding of the structures and functions of biological systems at both the cellular and subcellular levels. Recently, Brillouin microscopy,…

The precision of Cosmic Microwave Background (CMB) experiments, specifically its lensing reconstruction, has reached the limit where non-linear corrections cannot be ignored. Neglecting these corrections results in biased constraints on…

宇宙学与河外天体物理 · 物理学 2025-02-27 Cynthia Trendafilova , Ali Rida Khalife , Silvia Galli

Low-noise lasers are of central importance in a wide variety of applications, including high spectral-efficiency coherent communication protocols, distributed fibre sensing, and long distance coherent LiDAR. In addition to low phase noise,…

A lateral shear interferometer based digital holographic microscopy has been realized to study the morphology dynamics of Human red blood cells quantitatively. Here, a lateral shear interferometer is embedded with a conventional microscope…

图像与视频处理 · 电气工程与系统科学 2019-09-10 Shital Devinder , Ashish Lal , Tathagato Rai Dastidar , Satish Kumar Dubey

Deep-ultraviolet (DUV) microscopy can provide label-free biochemical contrast by exploiting the intrinsic absorption of nucleic acids, proteins and lipids, offering chemically specific morphological information that complements structural…

Addition of random phase to the object light is required in computer-generated holograms (CGHs) to widely diffuse the object light and to avoid its concentration on the CGH; however, this addition causes considerable speckle noise in the…

光学 · 物理学 2015-06-24 Tomoyoshi Shimobaba , Tomoyoshi Ito

Digital holographic microscopy is a thriving imaging modality that attracted considerable research interest in quantitative biological cell imaging due to its ability to not only create excellent label-free contrast, but also supply…

光学 · 物理学 2019-04-03 Gili Dardikman , Natan T. Shaked

Light-field fluorescence microscopy (LFM) is a powerful elegant compact method for long-term high-speed imaging of complex biological systems, such as neuron activities and rapid movements of organelles. LFM experiments typically generate…

图像与视频处理 · 电气工程与系统科学 2023-10-17 Changqing Su , Zihan Lin , You Zhou , Shuai Wang , Yuhan Gao , Chenggang Yan , Bo Xiong

We report the modification of a label-free image scanning microscope (ISM) to perform asynchronous 2D imaging at 24kHz while keeping the lateral resolution gain and background rejection of a regular label-free ISM setup. Our method uses a…

光学 · 物理学 2023-08-31 Duc-Minh Ta , Alberto Aguilar , Pierre Bon

Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional…

图像与视频处理 · 电气工程与系统科学 2024-05-24 Feng Wang , Renfang Wang , Hong Qiu

A technique of pulsed low-energy electron holography is introduced that allows for recording highly resolved holograms within reduced exposure times. Therefore, stacks of holograms are accumulated in a pulsed mode with individual…

仪器与探测器 · 物理学 2013-05-27 Matthias Germann , Tatiana Latychevskaia , Conrad Escher , Hans-Werner Fink

Second harmonic generation (SHG) microscopy is a valuable tool for optical microscopy. SHG microscopy is normally performed as a point scanning imaging method, which lacks phase information and is limited in spatial resolution by the…

Latent Diffusion models (LDMs) have achieved remarkable results in synthesizing high-resolution images. However, the iterative sampling process is computationally intensive and leads to slow generation. Inspired by Consistency Models (song…

计算机视觉与模式识别 · 计算机科学 2023-10-09 Simian Luo , Yiqin Tan , Longbo Huang , Jian Li , Hang Zhao

Three-dimensional (3D) imaging of the subcellular organisation and morphology of cells and tissues is essential for understanding biological function. Although staining is the most widely used approach for visualising biological samples…

The field of computational imaging has witnessed a promising paradigm shift with the emergence of untrained neural networks, offering novel solutions to inverse computational imaging problems. While existing techniques have demonstrated…

图像与视频处理 · 电气工程与系统科学 2024-11-28 Abeer Banerjee , Sanjay Singh

Low-light imaging with handheld mobile devices is a challenging issue. Limited by the existing models and training data, most existing methods cannot be effectively applied in real scenarios. In this paper, we propose a new low-light image…

图像与视频处理 · 电气工程与系统科学 2021-03-02 Meng Chang , Huajun Feng , Zhihai Xu , Qi Li

Mid-infrared photothermal (MIP) microscopy has been a promising label-free chemical imaging technique for functional characterization of specimens owing to its enhanced spatial resolution and high specificity. Recently developed wide-field…

Low-light imaging on mobile devices is typically challenging due to insufficient incident light coming through the relatively small aperture, resulting in a low signal-to-noise ratio. Most of the previous works on low-light image processing…

图像与视频处理 · 电气工程与系统科学 2022-09-05 Yucheng Lu , Seung-Won Jung

This paper presents one of the case studies of the Gamma Factory initiative -- a proposal of a new operation scheme of ion beams in the CERN accelerator complex. Its goal is to extend the scope and precision of the LHC-based research by…

加速器物理 · 物理学 2020-06-01 Mieczyslaw Witold Krasny , Alexey Petrenko , Wieslaw Placzek