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In an era of escalating cyber threats, malware poses significant risks to individuals and organizations, potentially leading to data breaches, system failures, and substantial financial losses. This study addresses the urgent need for…

密码学与安全 · 计算机科学 2025-01-28 Marzieh Esnaashari , Nima Moradi

Antimicrobial-resistant (AMR) microbes are a growing challenge in healthcare, rendering modern medicines ineffective. AMR arises from antibiotic production and bacterial evolution, but quantifying its transmission remains difficult. With…

机器学习 · 计算机科学 2025-02-04 Qian Fu , Yuzhe Zhang , Yanfeng Shu , Ming Ding , Lina Yao , Chen Wang

Antibiotics are a vital class of drugs closely associated with the prevention and treatment of bacterial infections. Accurate prediction of molecular antimicrobial activity remains a key challenge in the pursuit of novel antibiotic…

定量方法 · 定量生物学 2025-09-23 R. He

Antimicrobial resistance is an important public health concern that has implications in the practice of medicine worldwide. Accurately predicting resistance phenotypes from genome sequences shows great promise in promoting better use of…

The role of direct cell-to-cell spread in viral infections - where virions spread between host and susceptible cells without needing to be secreted into the extracellular environment - has come to be understood as essential to the dynamics…

定量方法 · 定量生物学 2024-05-21 Thomas Williams , James M. McCaw , James Osborne

Viral infections are causing significant morbidity and mortality worldwide. Understanding the interaction patterns between a particular virus and human proteins plays a crucial role in unveiling the underlying mechanism of viral infection…

机器学习 · 计算机科学 2021-11-30 Thi Ngan Dong , Graham Brogden , Gisa Gerold , Megha Khosla

The aim of this paper is to study two models for a bacterial population subject to antibiotic treatments. It is known that some bacteria are sensitive to antibiotics. These bacteria are in a state called persistence and each bacterium can…

概率论 · 数学 2013-04-15 Fabio Zucca

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

机器学习 · 计算机科学 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

Malaria is a deadly disease which claims the lives of hundreds of thousands of people every year. Computational methods have been proven to be useful in the medical industry by providing effective means of classification of diagnostic…

计算机视觉与模式识别 · 计算机科学 2020-05-26 Rishabh Malhotra , Dhron Joshi , Ku Young Shin

Biomedical images are increasing drastically. Along the way, many machine learning algorithms have been proposed to predict and identify various kinds of diseases. One such disease is Pneumonia which is an infection caused by both bacteria…

图像与视频处理 · 电气工程与系统科学 2021-01-20 Sheikh Md Hanif Hossain , S M Raju , Amelia Ritahani Ismail

Diagnostic tests that can detect pre-clinical or sub-clinical infection, are one of the most powerful tools in our armoury of weapons to control infectious diseases. Considerable effort has been paid to improving diagnostic testing for…

Inclusion of high throughput technologies in the field of biology has generated massive amounts of biological data in the recent years. Now, transforming these huge volumes of data into knowledge is the primary challenge in computational…

机器学习 · 计算机科学 2021-12-06 Dibyendu Ghosh , Srija Chakraborty , Hariprasad Kodamana , Supriya Chakraborty

Quick and accurate medical diagnosis is crucial for the successful treatment of a disease. Using machine learning algorithms, we have built two models to predict a hematologic disease, based on laboratory blood test results. In one…

Blood cultures are often over ordered without clear justification, straining healthcare resources and contributing to inappropriate antibiotic use pressures worsened by the global shortage. In study of 135483 emergency department (ED) blood…

Predicting if red blood cells (RBC) are infected with the malaria parasite is an important problem in Pathology. Recently, supervised machine learning approaches have been used for this problem, and they have had reasonable success. In…

计算机视觉与模式识别 · 计算机科学 2020-10-05 Anik Khan , Kishor Datta Gupta , Deepak Venugopal , Nirman Kumar

Machine-learning algorithms can facilitate low-cost, user-guided visual diagnostic platforms for addressing disparities in access to sexual health services. We developed a clinical image dataset using original and augmented images for five…

图像与视频处理 · 电气工程与系统科学 2024-03-14 Lao-Tzu Allan-Blitz , Sithira Ambepitiya , Raghavendra Tirupathi , Jeffrey D. Klausner , Yudara Kularathne

Biological datasets amenable to applied machine learning are more available today than ever before, yet they lack adequate representation in the Data-for-Good community. Here we present a work in progress case study performing analysis on…

机器学习 · 统计学 2016-07-06 John W. Santerre , James J. Davis , Fangfang Xia , Rick Stevens

Antibiotic resistance constitutes a major health threat. Predicting bacterial causes of infections is key to reducing antibiotic misuse, a leading driver of antibiotic resistance. We train a machine learning algorithm on administrative and…

综合经济学 · 经济学 2019-06-10 Michael Allan Ribers , Hannes Ullrich

Hematological disorders, which involve a variety of malignant conditions and genetic diseases affecting blood formation, present significant diagnostic challenges. One such major challenge in clinical settings is differentiating…

图像与视频处理 · 电气工程与系统科学 2024-11-27 Buddhadev Goswami , Adithya B. Somaraj , Prantar Chakrabarti , Ravindra Gudi , Nirmal Punjabi

As machine-learning (ML) based systems for malware detection become more prevalent, it becomes necessary to quantify the benefits compared to the more traditional anti-virus (AV) systems widely used today. It is not practical to build an…

密码学与安全 · 计算机科学 2018-06-14 William Fleshman , Edward Raff , Richard Zak , Mark McLean , Charles Nicholas