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Whole brain segmentation with magnetic resonance imaging (MRI) enables the non-invasive measurement of brain regions, including total intracranial volume (TICV) and posterior fossa volume (PFV). Enhancing the existing whole brain…

图像与视频处理 · 电气工程与系统科学 2024-04-24 Xin Yu , Yucheng Tang , Qi Yang , Ho Hin Lee , Shunxing Bao , Yuankai Huo , Bennett A. Landman

Accurate segmentation of cerebral vasculature and a quantitative assessment of cerebrovascular morphology is critical to various diagnostic and therapeutic purposes and is pertinent to studying brain health and disease. However, this is…

定量方法 · 定量生物学 2020-02-27 Aditi Deshpande , Nima Jamilpour , Bin Jiang , Chelsea Kidwell , Max Wintermark , Kaveh Laksari

Higher-order properties of functional magnetic resonance imaging (fMRI) induced connectivity have been shown to unravel many exclusive topological and dynamical insights beyond pairwise interactions. Nonetheless, whether these fMRI-induced…

Automatic segmentation of diverse heterogeneous brain lesions using multi-modal MRI is a challenging problem in clinical neuroimaging, mainly because of the lack of generalizability and high prediction variance of pathology-specific deep…

计算机视觉与模式识别 · 计算机科学 2026-02-24 Md. Mehedi Hassan , Shafqat Alam , Shahriar Ahmed Seam , Maruf Ahmed

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

计算机视觉与模式识别 · 计算机科学 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

Methods for automatically flag poor performing-predictions are essential for safely implementing machine learning workflows into clinical practice and for identifying difficult cases during model training. We present a readily adoptable…

图像与视频处理 · 电气工程与系统科学 2023-05-17 Harrison C. Gottlich , Panagiotis Korfiatis , Adriana V. Gregory , Timothy L. Kline

Medical image segmentation is a cornerstone of modern clinical diagnostics. While Vision Transformers that leverage shifted window-based self-attention have established new benchmarks in this field, they are often hampered by a critical…

计算机视觉与模式识别 · 计算机科学 2025-12-04 Fuchen Zheng , Xinyi Chen , Weixuan Li , Quanjun Li , Junhua Zhou , Xiaojiao Guo , Xuhang Chen , Chi-Man Pun , Shoujun Zhou

Understanding the structure of the brain, and how it changes with time and disease, is a core goal of structural neuroimaging. Contemporary approaches to structural brain analysis are dominated by voxel-wise, mass-univariate methods such as…

代数拓扑 · 数学 2026-04-28 Donato Quiccione , Mariam Pirashvili , Nathan Broomhead , Sean J. Fallon

Tooth image segmentation is a cornerstone of dental digitization. However, traditional image encoders relying on fixed-resolution feature maps often lead to discontinuous segmentation and poor discrimination between target regions and…

计算机视觉与模式识别 · 计算机科学 2026-02-26 Xinxin Zhao , Jian Jiang , Yan Tian , Liqin Wu , Zhaocheng Xu , Teddy Yang , Yunuo Zou , Xun Wang

Photoacoustic imaging (PAI), by combining high optical contrast with ultrasonic resolution, offers a promising noninvasive approach for dynamic monitoring of cerebral vasculature. However, transcranial PAI still faces significant challenges…

Brain extraction is a fundamental step for most brain imaging studies. In this paper, we investigate the problem of skull stripping and propose complementary segmentation networks (CompNets) to accurately extract the brain from T1-weighted…

计算机视觉与模式识别 · 计算机科学 2018-10-11 Raunak Dey , Yi Hong

The hippocampus is often attributed to episodic memory formation and storage in the mammalian brain; in particular, Alme et al. showed that hippocampal area CA3 forms statistically independent representations across a large number of…

神经元与认知 · 定量生物学 2021-01-01 Bhav Jain , Sean Elliott

We propose a new iterative segmentation model which can be accurately learned from a small dataset. A common approach is to train a model to directly segment an image, requiring a large collection of manually annotated images to capture the…

计算机视觉与模式识别 · 计算机科学 2018-09-13 Danielle F. Pace , Adrian V. Dalca , Tom Brosch , Tal Geva , Andrew J. Powell , Jürgen Weese , Mehdi H. Moghari , Polina Golland

The need for large amounts of training data in modern machine learning is one of the biggest challenges of the field. Compared to the brain, current artificial algorithms are much less capable of learning invariance transformations and…

神经与进化计算 · 计算机科学 2023-07-25 Aleksandar Vučković , Benedikt Stock , Alexander V. Hopp , Mathias Winkel , Helmut Linde

Segmentation of anatomical regions of interest such as vessels or small lesions in medical images is still a difficult problem that is often tackled with manual input by an expert. One of the major challenges for this task is that the…

图像与视频处理 · 电气工程与系统科学 2021-12-15 Tianyu Ma , Hang Zhang , Hanley Ong , Amar Vora , Thanh D. Nguyen , Ajay Gupta , Yi Wang , Mert Sabuncu

Accurate geometry representation is essential in developing finite element models. Although generally good, deep-learning segmentation approaches with only few data have difficulties in accurately segmenting fine features, e.g., gaps and…

图像与视频处理 · 电气工程与系统科学 2022-08-19 Peidi Xu , Faezeh Moshfeghifar , Torkan Gholamalizadeh , Michael Bachmann Nielsen , Kenny Erleben , Sune Darkner

In this paper, we proposed and validated a fully automatic pipeline for hippocampal surface generation via 3D U-net coupled with active shape modeling (ASM). Principally, the proposed pipeline consisted of three steps. In the beginning, for…

神经与进化计算 · 计算机科学 2021-09-15 Pinyuan Zhong , Yue Zhang , Xiaoying Tang

Despite the superior performance of Deep Learning (DL) on numerous segmentation tasks, the DL-based approaches are notoriously overconfident about their prediction with highly polarized label probability. This is often not desirable for…

图像与视频处理 · 电气工程与系统科学 2021-12-14 Sungmin Hong , Anna K. Bonkhoff , Andrew Hoopes , Martin Bretzner , Markus D. Schirmer , Anne-Katrin Giese , Adrian V. Dalca , Polina Golland , Natalia S. Rost

Automatic methods for measuring normalized regional brain volumes from MRI data are a key tool to help in the objective diagnostic and follow-up of many neurological diseases. To estimate such regional brain volumes, the intracranial cavity…

Alterations in structural brain laterality are reported in attention-deficit/hyperactivity disorder (ADHD). However, few studies examined differences within presentations of ADHD. We investigate asymmetry index (AI) across 13 subcortical…

神经元与认知 · 定量生物学 2020-10-27 Cintya Nirvana Dutta , Pamela K. Douglas , Hernando Ombao