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Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

计算机视觉与模式识别 · 计算机科学 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

Early diagnosis of cancer often allows for a more vast choice of therapy opportunities. After a cancer diagnosis, staging provides essential information about the extent of disease in the body and the expected response to a particular…

计算机视觉与模式识别 · 计算机科学 2020-08-06 Mario D'Acunto , Massimo Martinelli , Davide Moroni

Computational cytology is a critical, rapid-developing, yet challenging topic in the field of medical image computing which analyzes the digitized cytology image by computer-aided technologies for cancer screening. Recently, an increasing…

图像与视频处理 · 电气工程与系统科学 2023-03-21 Hao Jiang , Yanning Zhou , Yi Lin , Ronald CK Chan , Jiang Liu , Hao Chen

Although melanoma occurs more rarely than several other skin cancers, patients' long term survival rate is extremely low if the diagnosis is missed. Diagnosis is complicated by a high discordance rate among pathologists when distinguishing…

The most prevalent form of bladder cancer is urothelial carcinoma, characterized by a high recurrence rate and substantial lifetime treatment costs for patients. Grading is a prime factor for patient risk stratification, although it suffers…

图像与视频处理 · 电气工程与系统科学 2024-05-27 Saul Fuster , Umay Kiraz , Trygve Eftestøl , Emiel A. M. Janssen , Kjersti Engan

Purpose: To evaluate the quality of deep learning reconstruction for prospectively accelerated intraoperative magnetic resonance imaging (iMRI) during resective brain tumor surgery. Materials and Methods: Accelerated iMRI was performed…

Rapid advances of hardware-based technologies during the past decades have opened up new possibilities for Life scientists to gather multimodal data in various application domains (e.g., Omics, Bioimaging, Medical Imaging, and…

机器学习 · 计算机科学 2018-01-09 Mufti Mahmud , M. Shamim Kaiser , Amir Hussain , Stefano Vassanelli

In this paper, the effectiveness and capability of convolutional neural networks have been studied in the classification of 8 skin diseases. Different pre-trained state-of-the-art architectures (DenseNet 201, ResNet 152, Inception v3,…

计算机视觉与模式识别 · 计算机科学 2018-10-25 Amirreza Rezvantalab , Habib Safigholi , Somayeh Karimijeshni

Cancers are characterized by remarkable heterogeneity and diverse prognosis. Accurate cancer classification is essential for patient stratification and clinical decision-making. Although digital pathology has been advancing cancer diagnosis…

计算机视觉与模式识别 · 计算机科学 2025-02-13 Xiaofei Wang , Hanyu Liu , Yupei Zhang , Boyang Zhao , Hao Duan , Wanming Hu , Yonggao Mou , Stephen Price , Chao Li

Recent advances in experimental methods have enabled researchers to collect data on thousands of analytes simultaneously. This has led to correlational studies that associated molecular measurements with diseases such as Alzheimer's, Liver,…

定量方法 · 定量生物学 2024-05-20 Divyagna Bavikadi , Ayushi Agarwal , Shashank Ganta , Yunro Chung , Lusheng Song , Ji Qiu , Paulo Shakarian

Accurate prediction of recurrence in clear cell renal cell carcinoma (ccRCC) remains a major clinical challenge due to the disease complex molecular, pathological, and clinical heterogeneity. Traditional prognostic models, which rely on…

图像与视频处理 · 电气工程与系统科学 2025-07-11 Hasaan Maqsood , Saif Ur Rehman Khan

Cancer is a complex disease, the understanding and treatment of which are being aided through increases in the volume of collected data and in the scale of deployed computing power. Consequently, there is a growing need for the development…

Deep learning (DL) models have achieved paradigm-changing performance in many fields with high dimensional data, such as images, audio, and text. However, the black-box nature of deep neural networks is a barrier not just to adoption in…

机器学习 · 计算机科学 2020-02-25 Parmita Mehta , Stephen Portillo , Magdalena Balazinska , Andrew Connolly

Deep Learning (DL) algorithms hold great promise for applications in the field of computational biophysics. In fact, the vast amount of available molecular structures, as well as their notable complexity, constitutes an ideal context in…

软凝聚态物质 · 物理学 2019-01-07 Marco Giulini , Raffaello Potestio

Over one in three people are affected by neurodegenerative disorders. Neural stem cells, which are multipotent regenerative cells with the potential to differentiate into any of the neural cell types, have immense therapeutic potential for…

图像与视频处理 · 电气工程与系统科学 2024-09-27 Nidhi Parthasarathy , Chandra Suda , Anika Mittal , Ian Young Chen , Ananya Jalihal

Convolutional neural networks (CNNs) have shown great promise in improving computer aided detection (CADe). From classifying tumors found via mammography as benign or malignant to automated detection of colorectal polyps in CT colonography,…

计算机视觉与模式识别 · 计算机科学 2019-07-30 Hunter Park , Connor Monahan

To address the issues of limited samples, time-consuming feature design, and low accuracy in detection and classification of breast cancer pathological images, a breast cancer image classification model algorithm combining deep learning and…

图像与视频处理 · 电气工程与系统科学 2024-09-12 Weimin Wang , Yufeng Li , Xu Yan , Mingxuan Xiao , Min Gao

Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make…

Aim: Early detection and correct diagnosis of lung cancer are the most important steps in improving patient outcome. This study aims to assess which deep learning models perform best in lung cancer diagnosis. Methods: Non-small cell lung…

计算机视觉与模式识别 · 计算机科学 2018-03-16 Zhang Li , Zheyu Hu , Jiaolong Xu , Tao Tan , Hui Chen , Zhi Duan , Ping Liu , Jun Tang , Guoping Cai , Quchang Ouyang , Yuling Tang , Geert Litjens , Qiang Li

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

计算机视觉与模式识别 · 计算机科学 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu