相关论文: Differential Co-Abundance Network Analyses for Mic…

Mixed-membership (MM) models such as Latent Dirichlet Allocation (LDA) have been applied to microbiome compositional data to identify latent subcommunities of microbial species. These subcommunities are informative for understanding the…

We present the first meta-analysis of co-evolutionary learning networks for digital disease surveillance research over last 10 years. In doing so, we show the co-evolution and dynamical changes that occurred in academic research related to…

The clinical deployment of deep learning models for high-stakes tasks such as diabetic retinopathy (DR) grading requires demonstrable reliability. While models achieve high accuracy, their clinical utility is limited by a lack of robust…

In cancer research, the comparison of gene expression or DNA methylation networks inferred from healthy controls and patients can lead to the discovery of biological pathways associated to the disease. As a cancer progresses, its signalling…

Serotonergic neurons in the raphe nuclei exhibit diverse electrophysiological properties and functional roles, yet conventional identification methods rely on restrictive criteria that likely overlook atypical serotonergic cells. The use of…

Functional Data Analysis (FDA) is a statistical domain developed to handle functional data characterized by high dimensionality and complex data structures. Sequential Neural Networks (SNNs) are specialized neural networks capable of…

Medical image segmentation using deep neural networks has been highly successful. However, the effectiveness of these networks is often limited by inadequate dense prediction and inability to extract robust features. To achieve refined…

Motivated by the gene co-expression pattern analysis, we propose a novel sample quantile-based contingency (squac) statistic to infer quantile associations conditioning on covariates. It features enhanced flexibility in handling variables…

As sequencing technologies become more affordable and genomic databases expand continuously, the reuse of publicly available sequencing data emerges as a powerful strategy for studying microbial pathogens. Indeed, raw sequencing reads…

Deep Neural Networks (DNNs) show a significant impact on medical imaging. One significant problem with adopting DNNs for skin cancer classification is that the class frequencies in the existing datasets are imbalanced. This problem hinders…

We introduce the Differentiable Weightless Neural Network (DWN), a model based on interconnected lookup tables. Training of DWNs is enabled by a novel Extended Finite Difference technique for approximate differentiation of binary values. We…

Medical Ultrasound (US) is one of the most widely used imaging modalities in clinical practice, but its usage presents unique challenges such as variable imaging quality. Deep Learning (DL) models can serve as advanced medical US image…

Survival analysis, the art of time-to-event modeling, plays an important role in clinical treatment decisions. Recently, continuous time models built from neural ODEs have been proposed for survival analysis. However, the training of neural…

Advances in remote sensing technology have led to the capture of massive amounts of data. Increased image resolution, more frequent revisit times, and additional spectral channels have created an explosion in the amount of data that is…

The detection and classification of diseases in Robusta coffee leaves are essential to ensure that plants are healthy and the crop yield is kept high. However, this job requires extensive botanical knowledge and much wasted time. Therefore,…

Standard Convolutional Neural Network (CNN) designs rarely focus on the importance of explicitly capturing diverse features to enhance the network's performance. Instead, most existing methods follow an indirect approach of increasing or…

Mutual Information (MI) has been widely used as a loss regularizer for training neural networks. This has been particularly effective when learn disentangled or compressed representations of high dimensional data. However, differential…

Network biology has been successfully used to help reveal complex mechanisms of disease, especially cancer. On the other hand, network biology requires in-depth knowledge to construct disease-specific networks, but our current knowledge is…

Purpose: Spiking neural networks (SNNs) have recently gained attention as energy-efficient, biologically plausible alternatives to conventional deep learning models. Their application in high-stakes biomedical imaging remains almost…

Data augmentation plays a key role in modern machine learning pipelines. While numerous augmentation strategies have been studied in the context of computer vision and natural language processing, less is known for other data modalities.…