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相关论文: Computable Phenotypes for Post-acute sequelae of S…

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Accurately and efficiently diagnosing Post-Acute Sequelae of COVID-19 (PASC) remains challenging due to its myriad symptoms that evolve over long- and variable-time intervals. To address this issue, we developed a hybrid natural language…

Through the use of cutting-edge unsupervised classification techniques from statistics and machine learning, we characterise symptom phenotypes among symptomatic SARS-CoV-2 PCR-positive community cases. We first analyse each dataset in…

Moderate to severe post-acute sequelae of SARS-CoV-2 infection (PASC), also called long COVID, is estimated to impact as many as 10% of SARS-CoV-2 infected individuals, representing a chronic condition with a substantial global public…

统计方法学 · 统计学 2024-10-11 Harrison T. Reeder , Tanayott Thaweethai , Andrea S. Foulkes

The long-term effects of Postacute Sequelae of SARS-CoV-2, known as PASC, pose a significant challenge to healthcare systems worldwide. Accurate identification of progression events, such as hospitalization and reinfection, is essential for…

机器学习 · 计算机科学 2025-07-01 Jing Wang , Amar Sra , Jeremy C. Weiss

Post-COVID Syndrome (PCS), encompassing the multifaceted sequelae of COVID-19, can be severity-graded using a score comprising 12 different long-term symptom complexes. Acute COVID-19 severity and individual resilience were previously…

Early prediction of Post-Acute Sequelae of SARS-CoV-2 severity is a critical challenge for women's health, particularly given the diagnostic overlap between PASC and common hormonal transitions such as menopause. Identifying and accounting…

机器学习 · 计算机科学 2026-03-19 Jing Wang , Jie Shen , Yiming Luo , Amar Sra , Qiaomin Xie , Jeremy C. Weiss

Post-acute sequelae of SARS-CoV-2 infection (Long COVID) frequently persists for months, yet drivers of clinical remission remain incompletely defined. Here we analyzed 97,564 longitudinal PASC assessments from 13,511 participants with…

其他定量生物学 · 定量生物学 2026-01-14 Jing Wang , Tong Zhang , Xing Niu , Jie Shen , Yiming Luo , Qiaomin Xie , Amar Sra , Zorina Galis , Jeremy Weiss

It is shown that various symptoms could remain in the stage of post-acute sequelae of SARS-CoV-2 infection (PASC), otherwise known as Long COVID. A number of COVID patients suffer from heterogeneous symptoms, which severely impact recovery…

定量方法 · 定量生物学 2022-11-17 Sihang Jiang , Johanna Loomba , Suchetha Sharma , Donald Brown

While the acute phase of the COVID-19 pandemic has subsided, its long-term effects persist through Post-Acute Sequelae of COVID-19 (PASC), commonly known as Long COVID. There remains substantial uncertainty regarding both its duration and…

T-cells are central to SARS-CoV-2 clearance and immunological memory, yet their contribution to the persistence of post-acute sequelae of COVID-19 (PASC) remains poorly understood. The immunological features that distinguish individuals who…

Based on recent studies, some COVID-19 symptoms can persist for months after infection, leading to what is termed long COVID. Factors such as vaccination timing, patient characteristics, and symptoms during the acute phase of infection may…

机器学习 · 计算机科学 2025-04-30 Milad Leyli-abadi , Jean-Patrick Brunet , Axel Tahmasebimoradi

The clinical spectrum of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the strain of coronavirus that caused the COVID-19 pandemic, is broad, extending from asymptomatic infection to severe immunopulmonary reactions that, if…

定量方法 · 定量生物学 2022-07-18 Aaron Wang , Feng Li , Samantha Chiang , Jennifer Fulcher , Otto Yang , David Wong , Fang Wei

The availability of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus data post-COVID has reached exponentially to an enormous magnitude, opening research doors to analyze its behavior. Various studies are conducted by…

神经与进化计算 · 计算机科学 2025-01-28 Taslim Murad , Prakash Chourasia , Sarwan Ali , Imdad Ullah Khan , Murray Patterson

The epidemic of COVID-19 has caused an unpredictable and devastated disaster to the public health in different territories around the world. Common phenotypes include fever, cough, shortness of breath, and chills. With more cases…

其他定量生物学 · 定量生物学 2020-08-06 Yang Wang , Fengwei Zhang , Hong Yu , Xianwei Ye , Yongqun He

Coronavirus Disease 2019 (COVID-19) is a rapidly emerging respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Due to the rapid human-to-human transmission of SARS-CoV-2, many healthcare systems…

机器学习 · 计算机科学 2020-12-01 Patrick Schwab , August DuMont Schütte , Benedikt Dietz , Stefan Bauer

Identifying long COVID symptoms is a challenging task, primarily due to the reliance on patient reports and the lack of disease specific biomarkers. The objective of this study is to identify individual long COVID symptoms, post COVID 19…

其他定量生物学 · 定量生物学 2025-10-02 Abdi Reza

To identify patients who are hospitalized because of COVID-19 as opposed to those who were admitted for other indications, we compared the performance of different computable phenotype definitions for COVID-19 hospitalizations that use…

For infectious diseases, characterizing symptom duration is of clinical and public health importance. Symptom duration may be assessed by surveying infected individuals and querying symptom status at the time of survey response. For…

Post-acute sequelae of SARS-CoV-2 infection (PASC) or Long COVID is an emerging medical condition that has been observed in several patients with a positive diagnosis for COVID-19. Historical Electronic Health Records (EHR) like diagnosis…

Background: Providing appropriate care for people suffering from COVID-19, the disease caused by the pandemic SARS-CoV-2 virus is a significant global challenge. Many individuals who become infected have pre-existing conditions that may…

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