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Cox proportional hazard model (CPH) is commonly used in clinical research for survival analysis. In quantitative medical imaging (radiomics) studies, CPH plays an important role in feature reduction and modeling. However, the underlying…

Traditional survival models such as the Cox proportional hazards model are typically based on scalar or categorical clinical features. With the advent of increasingly large image datasets, it has become feasible to incorporate quantitative…

计算机视觉与模式识别 · 计算机科学 2020-01-09 Christoph Haarburger , Philippe Weitz , Oliver Rippel , Dorit Merhof

This study proposed a hybrid model of a convolutional neural network (CNN) and a Transformer to predict and diagnose heart disease. Based on CNN's strength in detecting local features and the Transformer's high capacity in sensing global…

机器学习 · 计算机科学 2025-03-05 Ran Hao , Yanlin Xiang , Junliang Du , Qingyuan He , Jiacheng Hu , Ting Xu

Lung cancer remains one of the leading causes of cancer-related mortality, yet most survival models rely only on baseline factors and overlook posttreatment variables that reflect disease progression. To address this gap, we applied Cox…

应用统计 · 统计学 2025-10-03 Varun Vishwanathan Nair , Victor Miranda Soberanis

The most deadly and life-threatening disease in the world is lung cancer. Though early diagnosis and accurate treatment are necessary for lowering the lung cancer mortality rate. A computerized tomography (CT) scan-based image is one of the…

图像与视频处理 · 电气工程与系统科学 2023-04-12 Muntasir Mamun , Md Ishtyaq Mahmud , Mahabuba Meherin , Ahmed Abdelgawad

Recent studies have highlighted the high correlation between cardiovascular diseases (CVD) and lung cancer, and both are associated with significant morbidity and mortality. Low-Dose CT (LCDT) scans have led to significant improvements in…

计算机视觉与模式识别 · 计算机科学 2019-11-27 Hengtao Guo , Uwe Kruger , Ge Wang , Mannudeep K. Kalra , Pingkun Yan

Recent radiomic studies have witnessed promising performance of deep learning techniques in learning radiomic features and fusing multimodal imaging data. Most existing deep learning based radiomic studies build predictive models in a…

计算机视觉与模式识别 · 计算机科学 2019-01-08 Hongming Li , Pamela Boimel , James Janopaul-Naylor , Haoyu Zhong , Ying Xiao , Edgar Ben-Josef , Yong Fan

Lung cancer is a major cause of cancer-related deaths, and early diagnosis and treatment are crucial for improving patients' survival outcomes. In this paper, we propose to employ convolutional neural networks to model the non-linear…

图像与视频处理 · 电气工程与系统科学 2024-08-20 Xiawei Wang , James Sharpnack , Thomas C. M. Lee

Accurate survival prediction in head and neck cancer (HNC) is essential for guiding clinical decision-making and optimizing treatment strategies. Traditional models, such as Cox proportional hazards, have been widely used but are limited in…

计算机视觉与模式识别 · 计算机科学 2024-10-30 Aiman Farooq , Utkarsh Sharma , Deepak Mishra

Most prediction models that are used in medical research fail to accurately predict health outcomes due to methodological limitations. Using routinely collected patient data, we explore the use of a Cox proportional hazard (PH) model within…

统计方法学 · 统计学 2019-07-19 John Mbotwa , Marc de Kamps , Paul D. Baxter , Mark S. Gilthorpe

One of the most common ways researchers compare survival outcomes across treatments when confounding is present is using Cox regression. This model is limited by its underlying assumption of proportional hazards; in some cases, substantial…

应用统计 · 统计学 2021-02-02 Elizabeth A. Handorf , Marc Smaldone , Sujana Movva , Nandita Mitra

Recent studies have shown that lung cancer screening using annual low-dose computed tomography (CT) reduces lung cancer mortality by 20% compared to traditional chest radiography. Therefore, CT lung screening has started to be used widely…

图像与视频处理 · 电气工程与系统科学 2021-07-13 Gorkem Polat , Yesim Dogrusoz Serinagaoglu , Ugur Halici

Predicting the likelihood of survival is of paramount importance for individuals diagnosed with cancer as it provides invaluable information regarding prognosis at an early stage. This knowledge enables the formulation of effective…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Numan Saeed , Muhammad Ridzuan , Fadillah Adamsyah Maani , Hussain Alasmawi , Karthik Nandakumar , Mohammad Yaqub

Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Aiman Farooq , Deepak Mishra , Santanu Chaudhury

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

计算机视觉与模式识别 · 计算机科学 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

计算机视觉与模式识别 · 计算机科学 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

Listening to lung sounds through auscultation is vital in examining the respiratory system for abnormalities. Automated analysis of lung auscultation sounds can be beneficial to the health systems in low-resource settings where there is a…

信号处理 · 电气工程与系统科学 2020-09-10 Samiul Based Shuvo , Shams Nafisa Ali , Soham Irtiza Swapnil , Taufiq Hasan , Mohammed Imamul Hassan Bhuiyan

Chest radiographs are primarily employed for the screening of pulmonary and cardio-/thoracic conditions. Being undertaken at primary healthcare centers, they require the presence of an on-premise reporting Radiologist, which is a challenge…

计算机视觉与模式识别 · 计算机科学 2020-04-27 Arka Mitra , Arunava Chakravarty , Nirmalya Ghosh , Tandra Sarkar , Ramanathan Sethuraman , Debdoot Sheet

Lung Cancer is the most common cause of cancer-related death worldwide. Early and automatic diagnosis of Solitary Pulmonary Nodules (SPN) in Computer Tomography (CT) chest scans can provide early treatment as well as doctor liberation from…

图像与视频处理 · 电气工程与系统科学 2020-03-31 Ioannis D. Apostolopoulos

Lung cancer is the leading cause of cancer-related mortality worldwide. Lung cancer screening (LCS) using annual low-dose computed tomography (CT) scanning has been proven to significantly reduce lung cancer mortality by detecting cancerous…

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