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Mixture priors provide an intuitive way to incorporate historical data while accounting for potential prior-data conflict by combining an informative prior with a non-informative prior. However, pre-specifying the mixing weight for each…

统计方法学 · 统计学 2023-09-11 Peng Yang , Yuansong Zhao , Lei Nie , Jonathon Vallejo , Ying Yuan

In clinical trials, there often exist multiple historical studies for the same or related treatment investigated in the current trial. Incorporating historical data in the analysis of the current study is of great importance, as it can help…

统计方法学 · 统计学 2021-02-02 Huaqing Jin , Guosheng Yin

Machine learning models often perform poorly under subpopulation shifts in the data distribution. Developing methods that allow machine learning models to better generalize to such shifts is crucial for safe deployment in real-world…

机器学习 · 统计学 2024-03-18 Tim G. J. Rudner , Ya Shi Zhang , Andrew Gordon Wilson , Julia Kempe

Power-expected-posterior (PEP) methodology, which borrows ideas from the literature on power priors, expected-posterior priors and unit information priors, provides a systematic way to construct objective priors. The basic idea is to use…

统计方法学 · 统计学 2021-12-07 Anupreet Porwal , Abel Rodriguez

High-throughput preclinical perturbation screens, where the effects of genetic, chemical, or environmental perturbations are systematically tested on disease models, hold significant promise for machine learning-enhanced drug discovery due…

The behavior of many complex systems, from nanostructured materials to animal colonies, is governed by local transitions that, while involving a restricted number of interacting units, may generate collective cascade phenomena. Tracking…

Demonstrations provide insight into relevant state or action space regions, bearing great potential to boost the efficiency and practicality of reinforcement learning agents. In this work, we propose to leverage demonstration datasets by…

机器学习 · 计算机科学 2023-03-15 Jonas Gehring , Deepak Gopinath , Jungdam Won , Andreas Krause , Gabriel Synnaeve , Nicolas Usunier

Databases often contain corrupted, degraded, and noisy data with duplicate entries across and within each database. Such problems arise in citations, medical databases, genetics, human rights databases, and a variety of other applied…

统计方法学 · 统计学 2015-04-29 Rebecca C. Steorts

Linear mixed models (LMMs) have emerged as the method of choice for confounded genome-wide association studies. However, the performance of LMMs in non-randomly ascertained case-control studies deteriorates with increasing sample size. We…

基因组学 · 定量生物学 2016-02-23 Omer Weissbrod , Christoph Lippert , Dan Geiger , David Heckerman

The prior distribution for the unknown model parameters plays a crucial role in the process of statistical inference based on Bayesian methods. However, specifying suitable priors is often difficult even when detailed prior knowledge is…

统计方法学 · 统计学 2020-03-18 Marcelo Hartmann , Georgi Agiashvili , Paul Bürkner , Arto Klami

While Bayesian methods are praised for their ability to incorporate useful prior knowledge, in practice, convenient priors that allow for computationally cheap or tractable inference are commonly used. In this paper, we investigate the…

机器学习 · 统计学 2017-07-14 Willie Neiswanger , Eric Xing

Learning relational tabular data has gained significant attention recently, but most studies focus on single tables, overlooking the potential of cross-table learning. Cross-table learning, especially in scenarios where tables lack shared…

机器学习 · 计算机科学 2025-02-17 Zhaomin Wu , Shida Wang , Ziyang Wang , Bingsheng He

Use of historical data and real-world evidence holds great potential to improve the efficiency of clinical trials. One major challenge is how to effectively borrow information from historical data while maintaining a reasonable type I…

统计方法学 · 统计学 2020-12-15 Liyun Jiang , Lei Nie , Ying Yuan

There has been increased interest in using prior information in statistical analyses. For example, in rare diseases, it can be difficult to establish treatment efficacy based solely on data from a prospective study due to low sample sizes.…

统计方法学 · 统计学 2021-07-26 Ethan M. Alt , Matthew A. Psioda , Joseph G. Ibrahim

We propose the variable selection procedure incorporating prior constraint information into lasso. The proposed procedure combines the sample and prior information, and selects significant variables for responses in a narrower region where…

统计方法学 · 统计学 2011-02-19 Shurong Zheng , Guodong Song , Ning-Zhong Shi

In this paper, we study local information privacy (LIP), and design LIP based mechanisms for statistical aggregation while protecting users' privacy without relying on a trusted third party. The notion of context-awareness is incorporated…

密码学与安全 · 计算机科学 2020-12-01 Bo Jiang , Ming Li , Ravi Tandon

Probabilistic Latent Semantic Analysis is a novel statistical technique for the analysis of two-mode and co-occurrence data, which has applications in information retrieval and filtering, natural language processing, machine learning from…

机器学习 · 计算机科学 2013-01-30 Thomas Hofmann

Left censoring can occur with relative frequency when analysing recurrent events in epidemiological studies, especially observational ones. Concretely, the inclusion of individuals that were already at risk before the effective initiation…

统计方法学 · 统计学 2021-02-24 Gilma Hernández-Herrera , David Moriña , Albert Navarro

LTEs uplink (UL) efficiency critically depends on how the interference across different cells is controlled. The unique characteristics of LTEs modulation and UL resource assignment poses considerable challenges in achieving this goal…

网络与互联网体系结构 · 计算机科学 2013-09-11 Supratim Deb , Pantelis Monogioudis

Data-efficient learning algorithms are essential in many practical applications where data collection is expensive, e.g., in robotics due to the wear and tear. To address this problem, meta-learning algorithms use prior experience about…

机器学习 · 计算机科学 2020-10-26 Jean Kaddour , Steindór Sæmundsson , Marc Peter Deisenroth