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The coupling of the internal mechanisms of cell polarization to cell shape deformations and subsequent cell crawling poses many interdisciplinary scientific challenges. Several mathematical approaches have been proposed to model the…

细胞行为 · 定量生物学 2023-11-08 Eduardo Moreno , Robert Großmann , Carsten Beta , Sergio Alonso

Collective oscillation of cells in a population has been reported under diverse biological contexts and with vastly different molecular constructs. Could there be common principles similar to those that govern spontaneous oscillation in…

细胞行为 · 定量生物学 2019-07-08 Shou-Wen Wang , Lei-Han Tang

Cells not only can be motile by crawling but are also capable of non-motility active motions like periodic contraction or pulsation. In this work, based on a Voronoi cell model, we show how this non-motility activity affects the structure,…

软凝聚态物质 · 物理学 2025-02-11 Zhu-Qin Li , Qun-Li Lei , Yu-qiang Ma

The spherical alga Volvox swims by means of flagella on thousands of surface somatic cells. This geometry and its large size make it a model organism for studying the fluid dynamics of multicellularity. Remarkably, when two nearby Volvox…

The goal of the present work is to propose an agent-based model that originally combines classical Vicsek-like polarity alignments and contact forces, as implemented in the framework developed by Maury and Venel in [Maury, Venel, 2011]. The…

数值分析 · 数学 2026-04-08 Laurent Navoret , Roxana Sublet , Marcela Szopos

Multicellular organisms comprise a diverse collection of stable tissues built from different cell types. It remains unclear how large numbers of interacting cells can precisely coordinate their gene expression during tissue…

生物物理 · 物理学 2022-10-31 Matthew Smart , Anton Zilman

Many biological systems consist of self-motile and passive agents both of which contribute to overall functionality. However, there are very few studies of the properties of such mixtures. Here we formulate a model for mixtures of…

软凝聚态物质 · 物理学 2015-05-25 Denis F. Hinz , Alexander Panchenko , Tae-Yeon Kim , Eliot Fried

Collective behaviour in living systems is observed across many scales, from bacteria to insects, to fish shoals. Zebrafish have emerged as a model system amenable to laboratory study. Here we report a three-dimensional study of the…

统计力学 · 物理学 2024-05-16 Yushi Yang , Francesco Turci , Erika Kague , Chrissy L. Hammond , John Russo , C. Patrick Royall

Epithelial cell clusters often move collectively on a substrate. Mechanical signals play a major role in organizing this behavior. There are a number of experimental observations in these systems which await a comprehensive explanation.…

生物物理 · 物理学 2021-01-22 Youyuan Deng , Herbert Levine , Xiaoming Mao , Leonard M. Sander

A striking feature of the collective behavior of spherical microswimmers is that for sufficiently strong self-propulsion they phase-separate into a dense cluster coexisting with a low-density dis- ordered surrounding. Extending our previous…

软凝聚态物质 · 物理学 2016-10-31 Johannes Blaschke , Maurice Maurer , Karthik Menon , Andreas Zöttl , Holger Stark

Many marine invertebrates have larval stages covered in linear arrays of beating cilia, which propel the animal while simultaneously entraining planktonic prey. These bands are strongly conserved across taxa spanning four major superphyla,…

流体动力学 · 物理学 2017-02-14 William Gilpin , Vivek N. Prakash , Manu Prakash

The large-scale collective behavior of biological systems can be characterized by macroscopic transport, which arises from the non-equilibrium microscopic interactions among individual constituents. A prominent example is the formation of…

统计力学 · 物理学 2025-07-29 Subhadip Chakraborti , Vasily Zaburdaev

The recent developments in the theory of rapidly rotating Bose atoms have been reviewed in this article. Rotation leads to the development of quantized-vortices, that cluster into a vortex array, exactly to how superfluid helium behaves.…

量子气体 · 物理学 2023-12-20 Moumita Indra , Sandip Mondal

Active matter comprises individually driven units that convert locally stored energy into mechanical motion. Interactions between driven units lead to a variety of non-equilibrium collective phenomena in active matter. One of such phenomena…

软凝聚态物质 · 物理学 2021-06-15 Mingji Huang , Wensi Hu , Siyuan Yang , Quan-Xing Liu , H. P. Zhang

Suspensions of unicellular microswimmers such as flagellated bacteria or motile algae exhibit spontaneous density heterogeneities at large enough concentrations. Based on the relative location of the biological actuation appendages i.e.…

软凝聚态物质 · 物理学 2017-11-27 Fabian Jan Schwarzendahl , Marco G. Mazza

Swimmers and self-propelled particles are physical models for the collective behaviour and motility of a wide variety of living systems, such as bacteria colonies, bird flocks and fish schools. Such artificial active materials are amenable…

We show that arbitrarily large polar flocks are susceptible to the presence of a single small obstacle. In a wide region of parameter space, the obstacle triggers counter-propagating dense bands leading to reversals of the flow. In very…

软凝聚态物质 · 物理学 2022-06-01 Joan Codina , Benoît Mahault , Hugues Chaté , Jure Dobnikar , Ignacio Pagonabarraga , Xia-qing Shi

We present a novel Monte Carlo simulation of the phase separation dynamics of a model fluid membrane. Such a phase segregation induces shape changes of the membrane and results in local `budding' under favourable conditions. We present a…

凝聚态物理 · 物理学 2007-05-23 P. B. Sunil Kumar , Madan Rao

We present a model for a biological reactor in which bacteria tend to aggregate in flocs, as encountered in wastewater treatment plants. The influence of this flocculation on the growth dynamics of the bacteria is studied. We argue that a…

种群与进化 · 定量生物学 2007-05-23 Bart Haegeman , Claude Lobry , Jerome Harmand

Active fluids such as bacterial swarms, self-propelled colloids, and cell tissues can all display complex spatio-temporal vortices that are reminiscent of inertial turbulence. This emergent behavior despite the overdamped nature of these…

流体动力学 · 物理学 2023-09-15 Amal Manoharan , Sanjay CP , Ashwin Joy
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