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The cytoplasm is a heterogeneous mixture containing many types of proteins that self-assemble into a wide variety of complexes. The accuracy and speed of cytoplasmic self-assembly is astonishing because it involves the correct…

统计力学 · 物理学 2025-11-21 Félix Benoist , Pablo Sartori

Functionalizing colloids with reactive DNA linkers is a versatile way of programming self-assembly. DNA selectivity provides direct control over colloid-colloid interactions allowing the engineering of structures such as complex crystals or…

软凝聚态物质 · 物理学 2019-02-26 Pritam Kumar Jana , Bortolo Matteo Mognetti

Algorithmic self-assembly, a generalization of crystal growth processes, has been proposed as a mechanism for autonomous DNA computation and for bottom-up fabrication of complex nanostructures. A `program' for growing a desired structure…

材料科学 · 物理学 2010-01-08 Rebecca Schulman , Erik Winfree

We characterize the self-assembly of colloidal particles with surface mobile DNA linkers under kinetically limited valence conditions. For this, we put forward a computer simulation model that captures quantitatively the interplay between…

软凝聚态物质 · 物理学 2022-10-26 Pedro A. Sánchez , Alessio Caciagli , Sofia S. Kantorovich , Erika Eiser

We study two mechanisms for the formation of protein patterns near membranes of living cells by mathematical modelling. Self-assembly of protein domains by electrostatic lipid-protein interactions is contrasted with self-organization due to…

细胞行为 · 定量生物学 2007-05-23 Karin John , Markus Baer

From cytoskeletal networks to tissues, many biological systems behave as active materials. Their composition and stress-generation is affected by chemical reaction networks. In such systems, the coupling between mechanics and chemistry…

生物物理 · 物理学 2024-09-25 Luca Barberi , Karsten Kruse

We present a new simulation technique to study systems of polymers functionalized by reactive sites that bind/unbind forming reversible linkages. Functionalized polymers feature self-assembly and responsive properties that are unmatched by…

软凝聚态物质 · 物理学 2018-04-18 Bernardo Oyarzún , Bortolo Matteo Mognetti

The precise control of complex reactions is critical for biological processes yet our inability to design for specific outcomes limits the development of synthetic analogues. Here, we leverage differentiable simulators to design nontrivial…

软凝聚态物质 · 物理学 2025-05-13 Ryan Krueger , Ella King , Michael Brenner

Self-assembly is the autonomous organization of components into patterns or structures: an essential ingredient of biology and a desired route to complex organization. At equilibrium, the structure is encoded through specific interactions,…

软凝聚态物质 · 物理学 2018-10-03 Antoine Aubret , Mena Youssef , Stefano Sacanna , Jérémie Palacci

The adaptive and surprising emergent properties of biological materials self-assembled in far-from-equilibrium environments serve as an inspiration for efforts to design nanomaterials and their properties. In particular, controlling the…

统计力学 · 物理学 2023-07-07 Shriram Chennakesavalu , Sreekanth K. Manikandan , Frank Hu , Grant M. Rotskoff

Colloids self-assemble into various organized superstructures determined by particle interactions. There is a tremendous progress in both the scientific understanding and applications of self-assemblies of single-type identical particles.…

软凝聚态物质 · 物理学 2016-09-23 Chenhui Peng , Taras Turiv , Yubing Guo , Sergij V. Shiyanovskii , Qi-Huo Wei , Oleg D. Lavrentovich

At the heart of the structured architecture and complex dynamics of biological systems are specific and timely interactions operated by biomolecules. In many instances, biomolecular agents are spatially confined to flexible lipid membranes…

软凝聚态物质 · 物理学 2020-01-08 Bortolo Mognetti , Pietro Cicuta , Lorenzo Di Michele

The self-assembly of anisotropic building blocks into complex spatial architectures is an important design strategy in material science but the mechanisms by which the anisotropic interactions influence the early-stage growth and formation…

软凝聚态物质 · 物理学 2026-05-05 Dillip Kumar Mohapatra , Teun W. J. Verouden , Janne-Mieke Meijer

The colloid cellular automata do not imitate the physical structure of colloids but are governed by logical functions derived from the colloids. We analyse the space-time complexity of Boolean circuits derived from the electrical responses…

The cornerstone of structural biology is the unique relationship between protein sequence and the 3D structure at equilibrium. Although intrinsically disordered proteins (IDPs) do not fold into a specific 3D structure, breaking this…

Cells and microorganisms employ dynamic shape changes to enable steering and avoidance for efficient spatial exploration and collective organization. In contrast, active colloids, their synthetic counterparts, currently lack similar…

软凝聚态物质 · 物理学 2025-01-03 Stefania Ketzetzi , Lorenzo Caprini , Vivien Willems , Laura Alvarez , Hartmut Löwen , Lucio Isa

Amorphous particulate matter constitutes a wide range of natural and synthetic materials. Despite this ubiquity, the way in which these systems' disordered microstructure couples to their often subtle and complex dynamical behavior is not…

软凝聚态物质 · 物理学 2026-03-09 Erin G. Teich , Jason Z. Kim , Dani S. Bassett

Herein, we describe new methods to produce colloidal particle chains of three stiffness regimes that can be observed on a single-particle level, that is, on the level of the monomers that make up the chain; the chains can even be observed…

Biological information processing is often carried out by complex networks of interconnected dynamical units. A basic question about such networks is that of reliability: if the same signal is presented many times with the network in…

混沌动力学 · 物理学 2015-06-11 Guillaume Lajoie , Kevin K. Lin , Eric Shea-Brown

Soft materials, such as colloidal suspensions, polymer solutions, and biological systems, are typically multicomponent mixtures of macromolecules and simpler components (e.g., microions, monomers, solvent) that can assemble into complex…

软凝聚态物质 · 物理学 2015-05-13 Alan R. Denton