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Objective: In randomized clinical trials, prediction models can be used to explore the relationships between patients' variables (e.g., clinical, pathological, or lifestyle variables, and also biomarker or genomic data) and treatment effect…

定量方法 · 定量生物学 2026-02-03 Elvire Roblin , Paul-Henry Cournède , Stefan Michiels

Survival analysis models the distribution of time until an event of interest, such as discharge from the hospital or admission to the ICU. When a model's predicted number of events within any time interval is similar to the observed number,…

机器学习 · 计算机科学 2021-01-15 Mark Goldstein , Xintian Han , Aahlad Puli , Adler J. Perotte , Rajesh Ranganath

Machine learning (ML) has revolutionized medical prognostics by integrating advanced algorithms with clinical data to enhance disease prediction, risk assessment, and patient outcome forecasting. This comprehensive review critically…

机器学习 · 计算机科学 2024-08-06 Michael Fascia

Multi-omics data present significant challenges for statistical inference due to the complex interdependencies among biological layers. In this paper, we introduce a novel Multi-Omics Factor-Adjusted Cox (MOFA-Cox) model for analyzing…

统计方法学 · 统计学 2025-10-07 Heyuan Zhang , Meiling Hao , Lianqiang Qu , Liuquan Sun

Deep neural networks have shown remarkable performance when trained on independent and identically distributed data from a fixed set of classes. However, in real-world scenarios, it can be desirable to train models on a continuous stream of…

机器学习 · 计算机科学 2023-09-04 Nicolas Michel , Giovanni Chierchia , Romain Negrel , Jean-François Bercher , Toshihiko Yamasaki

The usual parametric models for survival data are of the following form. Some parametrically specified hazard rate $\alpha(s,\theta)$ is assumed for possibly censored random life times $X_1^0,\ldots,X_n^0$; one observes only…

统计方法学 · 统计学 2026-03-25 Nils Lid Hjort

Accurate predictions of when a component will fail are crucial when planning maintenance, and by modeling the distribution of these failure times, survival models have shown to be particularly useful in this context. The presented…

机器学习 · 计算机科学 2024-03-28 Olov Holmer , Mattias Krysander , Erik Frisk

Purpose: We address the challenge of inaccurate parameter estimation in diffusion MRI when the signal-to-noise ratio (SNR) is very low, as in the spinal cord. The accuracy of conventional maximum-likelihood estimation (MLE) depends highly…

Predictive maintenance in manufacturing environments presents a challenging optimization problem characterized by extreme cost asymmetry, where missed failures incur costs roughly fifty times higher than false alarms. Predictive maintenance…

人工智能 · 计算机科学 2026-02-24 Shaunak Dhande , Chutian Ma , Giacinto Paolo Saggese , Paul Smith , Krishna Taduri

Survival analysis is a statistical technique used to estimate the time until an event occurs. Although it is applied across a wide range of fields, adjusting for reporting delays under practical constraints remains a significant challenge…

机器学习 · 统计学 2025-10-27 Yuta Shikuri , Hironori Fujisawa

Continual learning and few-shot learning are important frontiers in progress toward broader Machine Learning (ML) capabilities. Recently, there has been intense interest in combining both. One of the first examples to do so was the…

神经与进化计算 · 计算机科学 2024-07-10 Gideon Kowadlo , Abdelrahman Ahmed , Amir Mayan , David Rawlinson

Many applications require the collection of data on different variables or measurements over many system performance metrics. We term those broadly as measures or variables. Often data collection along each measure incurs a cost, thus it is…

统计方法学 · 统计学 2021-11-30 Donghui Yan , Zhiwei Qin , Songxiang Gu , Haiping Xu , Ming Shao

Background Study individuals may face repeated events overtime. However, there is no consensus around learning approaches to use in a high-dimensional framework for survival data (when the number of variables exceeds the number of…

统计方法学 · 统计学 2022-03-30 Juliette Murris , Anais Charles-Nelson , Audrey Lavenu , Sandrine Katsahian

Many major works in social science employ matching to make causal conclusions, but different matches on the same data may produce different treatment effect estimates, even when they achieve similar balance or minimize the same loss…

应用统计 · 统计学 2023-03-23 Marco Morucci , Cynthia Rudin

Survival analysis is a hotspot in statistical research for modeling time-to-event information with data censorship handling, which has been widely used in many applications such as clinical research, information system and other fields with…

机器学习 · 计算机科学 2018-11-14 Kan Ren , Jiarui Qin , Lei Zheng , Zhengyu Yang , Weinan Zhang , Lin Qiu , Yong Yu

Causal inference methods (instrumental variables, difference-in-differences, regression discontinuity, etc.) are primary tools used across many social science milieus. One area where their application has lagged however, is in the study of…

计量经济学 · 经济学 2026-04-22 Samuele Centorrino , Christopher F. Parmeter

Causal influence measures for machine learnt classifiers shed light on the reasons behind classification, and aid in identifying influential input features and revealing their biases. However, such analyses involve evaluating the classifier…

机器学习 · 计算机科学 2018-04-10 Shayak Sen , Piotr Mardziel , Anupam Datta , Matthew Fredrikson

Survival prediction of cancers is crucial for clinical practice, as it informs mortality risks and influences treatment plans. However, a static model trained on a single dataset fails to adapt to the dynamically evolving clinical…

机器学习 · 计算机科学 2026-01-21 Dianzhi Yu , Conghao Xiong , Yankai Chen , Wenqian Cui , Xinni Zhang , Yifei Zhang , Hao Chen , Joseph J. Y. Sung , Irwin King

A robust adaptive model predictive control (MPC) algorithm is presented for linear, time invariant systems with unknown dynamics and subject to bounded measurement noise. The system is characterized by an impulse response model, which is…

系统与控制 · 电气工程与系统科学 2019-11-21 Anilkumar Parsi , Andrea Iannelli , Mingzhou Yin , Mohammad Khosravi , Roy S. Smith

Survival analysis aims to predict the timing of future events across various fields, from medical outcomes to customer churn. However, the integration of clustering into survival analysis, particularly for precision medicine, remains…

机器学习 · 计算机科学 2024-05-28 Gabriel Buginga , Edmundo de Souza e Silva
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