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Nowadays, analyzing and reducing the ever larger astronomical datasets is becoming a crucial challenge, especially for long cumulated observation times. The INTEGRAL/SPI X-gamma-ray spectrometer is an instrument for which it is essential to…

天体物理仪器与方法 · 物理学 2013-05-27 L. Bouchet , P. Amestoy , A. Buttari , F. -H. Rouet , M. Chauvin

Recently, the dense correlation volume method achieves state-of-the-art performance in optical flow. However, the correlation volume computation requires a lot of memory, which makes prediction difficult on high-resolution images. In this…

计算机视觉与模式识别 · 计算机科学 2022-04-04 Zihua Zheng , Ni Nie , Zhi Ling , Pengfei Xiong , Jiangyu Liu , Hao Wang , Jiankun Li

The differential sparing of normal tissues relative to tumor control observed at ultra-high dose rates, referred to as the FLASH effect, has recently gained considerable attention. The therapeutic advantages of FLASH radiotherapy are…

Integrated sensing and communication (ISAC) is widely recognized as a pivotal enabling technique for the advancement of future wireless networks. This paper aims to efficiently exploit the inherent sparsity of echo signals for the…

信息论 · 计算机科学 2024-01-01 Zichao Xiao , Rang Liu , Ming Li , Wei Wang , Qian Liu

Purpose: Pencil beam scanning proton therapy is sensitive to respiratory motion, leading to potential dose inhomogeneities due to interplay effects. We developed and validated a predictive framework to assess interplay and motion robustness…

Cell-free massive multiple-input multiple-output (MIMO) is a promising cellular network. In this network, a large number of distributed and multi-antenna access points (APs) jointly serve many single antenna users using the same…

信号处理 · 电气工程与系统科学 2021-07-30 Deokhwan Han , Jeonghun Park , Namyoon Lee

In this paper, we proposed a method to optimize adaptive proton FLASH therapy (ADP FLASH) using modularized pin ridge filters (pRFs) by recycling module pins from the initial plan while reducing pRF adjustments in adaptive FLASH planning.…

We propose a simplification of the Optimized Effective Potential (OEP) applied to the Self Interaction Correction (SIC) scheme of Density Functional Theory (DFT). The new scheme fulfills several key formal properties and turns out to be…

其他凝聚态物理 · 物理学 2009-11-13 J. Messud , P. M. Dinh , P. -G. Reinhard , E. Suraud

Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…

Achieving effective synergy between radiotherapy and immunotherapy is critical for optimizing tumor control and treatment outcomes. To explore the underlying mechanisms of this synergy, we have investigated a novel treatment approach known…

定量方法 · 定量生物学 2025-04-23 Yixun Xing , Casey Moore , Debabrata Saha , Dan Nguyen , MaryLena Bleile , Xun Jia , Robert Timmerman , Hao Peng , Steve Jiang

In radiation therapy, mathematical methods have been used for optimizing treatment planning for delivery of sufficient dose to the cancerous cells while keeping the dose to critical surrounding structures minimal. This optimization problem…

医学物理 · 物理学 2015-06-16 Hamed Yarmand , David Craft

We propose a novel solution framework for inverse mixed-integer optimization based on analytic center concepts from interior point methods. We characterize the optimality gap of a given solution, provide structural results, and propose…

最优化与控制 · 数学 2025-04-08 Samir Elhedhli , Göksu Ece Okur

We apply the superiorization methodology to the intensity-modulated radiation therapy (IMRT) treatment planning problem. In superiorization, linear voxel dose inequality constraints are the fundamental modeling tool within which a…

医学物理 · 物理学 2022-07-28 Florian Barkmann , Yair Censor , Niklas Wahl

Beam orientation optimization (BOO) is a key component in the process of IMRT treatment planning. It determines to what degree one can achieve a good treatment plan quality in the subsequent plan optimization process. In this paper, we have…

医学物理 · 物理学 2015-05-27 Xun Jia , Chunhua Men , Yifei Lou , Steve B. Jiang

As depth increases, linear energy transfer (LET) rises toward the distal edge of the Bragg peak, boosting the radiobiological effectiveness (RBE). To manage the biological variation and limit normal-tissue damage, LET-modifying objective…

医学物理 · 物理学 2025-05-22 Lisa Seckler , Amit Ben Antony Bennan , Niklas Wahl

In-memory computing (IMC) has been shown to be a promising approach for solving binary optimization problems while significantly reducing energy and latency. Building on the advantages of parallel computation, we propose an IMC-compatible…

Purpose: VT is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. STAR has emerged as a non-invasive option for such patients. While photon-based STAR has…

This study presents a proof-of-concept for a novel Bayesian inverse method in a one-dimensional setting, aimed at proton beam therapy treatment verification. Our methodology is predicated on a hypothetical scenario wherein strategically…

应用统计 · 统计学 2023-11-21 Alexander M. G. Cox , Laura Hattam , Andreas E. Kyprianou , Tristan Pryer

In this paper we propose a solution to the need for a fast particle transport algorithm in Online Adaptive Proton Therapy capable of cheaply, but accurately computing the changes in patient dose metrics as a result of changes in the system…

医学物理 · 物理学 2022-08-26 Tiberiu Burlacu , Danny Lathouwers , Zoltán Perkó

The steep dose gradients obtained with pencil beam scanning allow for precise tumor targeting at the cost of high sensitivity to uncertainties. Robust optimization is commonly applied to mitigate uncertainties in density and patient setup,…

医学物理 · 物理学 2024-11-26 Ivar Bengtsson , Anders Forsgren , Albin Fredriksson , Ye Zhang