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Inverse spectroscopic optical coherence tomography (IS-OCT) methods apply inverse problem formulations to acquired spectra to estimate depth-resolved sample properties. In the current study, we modelled the time-frequency-distributions…

光学 · 物理学 2021-04-20 James Hope , Matthew Goodwin , Frederique Vanholsbeeck

Purpose: To improve target coverage and reduce the dose in the surrounding organs-at-risks (OARs), we developed an image-guided treatment method based on a precomputed library of treatment plans controlled and delivered in real-time.…

医学物理 · 物理学 2022-11-02 Valentin Hamaide , Kevin Souris , Damien Dasnoy , Francois Glineur , Benoit Macq

Physics-informed neural networks (PINNs) have emerged as a powerful tool for solving forward and inverse problems involving partial differential equations (PDEs) by incorporating physical laws into the training process. However, the…

机器学习 · 计算机科学 2025-12-15 Binghang Lu , Changhong Mou , Guang Lin

Inverse imaging problems that are ill-posed can be encountered across multiple domains of science and technology, ranging from medical diagnosis to astronomical studies. To reconstruct images from incomplete and distorted data, it is…

图像与视频处理 · 电气工程与系统科学 2023-11-30 Cesar F. Caiafa , Ramiro M. Irastorza

In this two-part paper, we present a novel framework and methodology to analyze data from certain image-based biochemical assays, e.g., ELISPOT and Fluorospot assays. In this first part, we start by presenting a physical partial…

信号处理 · 电气工程与系统科学 2018-10-19 Pol del Aguila Pla , Joakim Jaldén

Experimental results, supported by precise modelling, demonstrate optimisation of a plasma-based injector with intermediate laser pulse energy ($<1$ J), corresponding to a normalised vector potential $a_0 = 2.15$, using ionisation injection…

Conventional planning objectives in optimization of intensity-modulated radiotherapy treatment (IMRT) plans are designed to minimize the violation of dose-volume histogram (DVH) thresholds using penalty functions. Although successful in…

医学物理 · 物理学 2023-07-19 Lovisa Engberg , Kjell Eriksson , Anders Forsgren , Björn Hårdemark

FLASH radiotherapy (FLASH-RT) achieves tumor control comparable to conventional dose-rate irradiation (CONV-RT) while significantly reducing radiation damage to normal tissues. However, the physical conditions triggering the FLASH sparing…

Methods: A phase space file in a plane at 202 mm downstream of the beam exit window is generated through tuning parameters to match FDC results with measured or MCNPX Monte Carlo-simulated integrated depth-dose distribution (IDD) and…

医学物理 · 物理学 2023-01-11 Qianxia Wang , Uwe Titt , Radhe Mohan , Fada Guan , Yao Zhao , Ming Yang , Pablo Yepes

Intrinsic Frequency (IF) has recently been introduced as an ample signal processing method for analyzing carotid and aortic pulse pressure tracings. The IF method has also been introduced as an effective approach for the analysis of…

数值分析 · 数学 2017-08-03 Peyman Tavallali , Hana Koorehdavoudi , Joanna Krupa

Purpose: Respiratory motion and the interplay effect cause the dose delivered to a patient with spot-scanned proton therapy to differ from the dose planned for during optimization. A new 4D robust optimization methodology was developed…

Linear detectors such as zero forcing (ZF) or minimum mean square error (MMSE) are imperative for large/massive MIMO systems for both the downlink and uplink scenarios. However these linear detectors require matrix inversion which is…

信息论 · 计算机科学 2016-11-15 Vipul Gupta , Abhay Kumar Sah , A. K. Chaturvedi

Proton therapy provides superior dose conformity compared with photon radiotherapy, concentrating radiation within the tumor while sparing adjacent healthy tissue. This advantage has been most effectively realized for static tumors in…

医学物理 · 物理学 2025-10-09 Vivek Maradia , Nick Yue , Adam Molzahn , Jingqian Wang , Mark Pankuch , Serdar Charyyev , Billy W. Loo

In intensity-modulated radiation therapy, optimal intensity distributions of incoming beams are decomposed into linear combinations of leaf openings of a multileaf collimator (segments). In order to avoid inefficient dose delivery, the…

医学物理 · 物理学 2010-09-29 Antje Kiesel , Tobias Gauer

In this paper, a new peak-to-average power ratio (PAPR) reduction scheme for orthogonal frequency division multiplexing (OFDM) is proposed based on the selected mapping (SLM) scheme. The proposed SLM scheme generates alternative OFDM signal…

信息论 · 计算机科学 2012-03-26 Kee-Hoon Kim , Hyun-Bae Jeon , Jong-Seon No , Dong-Joon Shin

Microwave imaging is commonly based on the solution of linearized inverse scattering problems by matched filtering algorithms, i.e., by applying the adjoint of the forward scattering operator to the observation data. A more rigorous…

图像与视频处理 · 电气工程与系统科学 2024-12-23 Matthias M. Saurer , Han Na , Marius Brinkmann , Thomas F. Eibert

Proton FLASH therapy leverages ultra-high dose-rate radiation to enhance the sparing of organs at risk without compromising tumor control probability. To prepare for the delivery of high doses to targets, we aim to develop a deep…

Nonlinear parametric inverse problems appear in many applications and are typically very expensive to solve, especially if they involve many measurements. These problems pose huge computational challenges as evaluating the objective…

数值分析 · 数学 2020-03-25 Drayton Munster , Eric de Sturler

Atom interferometers require both high efficiency and robust performance in their mirror pulses under experimental inhomogeneities. In this work, we demonstrated that quantum optimal control designed mirror pulse significantly enhance…

量子物理 · 物理学 2026-01-26 Xueting Fang , Doudou Wang , Kun Yuan , Jie Deng , Qin Luo , Xiaochun Duan , Minkang Zhou , Lushuai Cao , Zhongkun Hu

Particle filtering for target tracking using multi-input multi-output (MIMO) pulse-Doppler radars faces three long-standing obstacles: a) the absence of reliable likelihood models for raw radar data; b) the computational and statistical…

信号处理 · 电气工程与系统科学 2025-12-11 Shixiong Wang , Wei Dai , Geoffrey Ye Li
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